TAP binding protein (tapasin)

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Synonym

TAP binding protein (tapasin), Tapasin precursor, TAPBP, TAP-associated protein, TAPA, NGS17, TAP-binding protein, TPSN, NGS-17, TPN

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:6.72 cerebellum:6.76 brain stem:6.62 corpus callosum/glia:6.72 pineal gland:- peripheral nerve:6.55 spine:6.57 retina:- eye:- artery/aorta:6.58 vein:6.86 lymphnode:6.82 peripheral blood:- spleen:6.69 thymus:6.33 bone marrow:6.48 adipose:6.74 bone:- skin:6.54
CAGE cerebrum:4.03 cerebellum:- brain stem:4.12 corpus callosum/glia:4.26 pineal gland:4.20 peripheral nerve:- spine:3.90 retina:- eye:- artery/aorta:4.52 vein:5.49 lymphnode:5.24 peripheral blood:- spleen:5.72 thymus:5.70 bone marrow:- adipose:5.37 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.56 placenta:6.87 prostate:6.31 ovary:6.66 testis:6.21 heart:6.54 muscle:6.44 esophagus:6.62 stomach:6.67 intestine:6.53 colon:6.69 liver/hepato:6.68 lung:6.63 bladder:- kidney:6.81 pituitary:6.66 thyroid/parathyroid:7.02 adrenal gland:6.89 pancreas:6.47 breast:6.73 salivary:6.78
CAGE uterus:4.57 placenta:5.17 prostate:5.05 ovary:4.78 testis:4.02 heart:4.80 muscle:4.21 esophagus:5.09 stomach:- intestine:5.73 colon:5.26     liver/hepato:5.61    lung:5.46 bladder:4.90 kidney:5.14 pituitary:3.90 thyroid/parathyroid:5.50 adrenal gland:- pancreas:4.40 breast:4.08 salivary:4.97
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_003190
Gene ID 6892
Unigene ID -
Probe set ID 213081_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000206208
ENSG00000231925
GTEx ID ENSG00000206208
ENSG00000231925

Orthologous Gene

Mouse[6]  NM_001025313, NM_009318
Rat[1]  NM_033098, NM_009318

Chromosomal Region

HSCHR6_MHC_DBB  [33,245,400  -  33,260,090]
6p21.32  [33,267,471  -  33,282,164]
HSCHR6_MHC_COX  [33,189,081  -  33,203,772]
HSCHR6_MHC_QBL  [33,196,314  -  33,211,013]
HSCHR6_MHC_MCF  [33,437,818  -  33,452,509]
LRG_114  [4,826  -  19,519]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8619474
8769474
8805302
9110174
9238042
9271576
9521053
9545232
9545376
9802609
10088603
10382748
10508608
10636848
11132161
11823531
11862402
11884415
11970875
11972874
12018464
12047747
12149238
12200052
12213826
12463753
12477932
12582157
12594855
12682852
12788224
13678524
14519625
14574404
14607930
14668790
14978101
15163903
15455354
15489334
15634919
15743475
16193070
16322289
16344560
16828748
17055437
17170699
17207965
17389020
17498802
17947644
18039656
18196518
18248301
18261958
18694960
19119025
19167761
19217216
19322201
19701894
19728311
19776380
19851445
20017190
20070606
20532727
20600451
21139048
21248040
21518758
21890473
21963094
21987572
22505724
22923333
23000965
23519916
23640800
23736108
23940558
24163410

Gene Ontology  (GO ID)

Biological Process

GO:0019885  antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0042590  antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0002479  antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002474  antigen processing and presentation of peptide antigen via MHC class I
GO:0006952  defense response
GO:0006955  immune response
GO:0050823  peptide antigen stabilization
GO:0006461  protein complex assembly
GO:0006890  retrograde vesicle-mediated transport, Golgi to ER

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0042824  MHC class I peptide loading complex
GO:0042825  TAP complex

Molecular Function

GO:0042288  MHC class I protein binding
GO:0042605  peptide antigen binding
GO:0015433  peptide antigen-transporting ATPase activity
GO:0005515  protein binding
GO:0046978  TAP1 binding
GO:0046979  TAP2 binding
GO:0051082  unfolded protein binding