telomeric repeat binding factor 2

Synonym

TRBF2, Telomeric repeat-binding factor 2, Telomeric repeat binding factor 2 (TRF2), TERF2, TTAGGG repeat-binding factor 2, Telomeric DNA-binding protein, TRF2, telomeric repeat binding factor 2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:7.57

cerebellum:7.93

brain stem:7.43

corpus callosum/glia:7.34

pineal gland:-

peripheral nerve:7.02

spine:7.33

retina:-

eye:-

artery/aorta:6.94

vein:6.81

lymphnode:7.21

peripheral blood:-

spleen:7.05

thymus:7.11

bone marrow:6.91

adipose:6.97

bone:-

skin:6.87

CAGE

cerebrum:3.69

cerebellum:-

brain stem:3.51

corpus callosum/glia:3.70

pineal gland:3.78

peripheral nerve:-

spine:3.33

retina:-

eye:-

artery/aorta:3.44

vein:3.32

lymphnode:3.49

peripheral blood:-

spleen:3.28

thymus:3.61

bone marrow:-

adipose:3.51

bone:-

skin:-

RNA-seq

cerebrum:4.09

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.41

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:3.48

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:7.21

placenta:6.28

prostate:7.07

ovary:7.15

testis:6.77

heart:6.52

muscle:6.97

esophagus:6.78

stomach:6.89

intestine:6.86

colon:6.87

liver/hepato:6.49

lung:6.65

bladder:-

kidney:6.71

pituitary:6.94

thyroid/parathyroid:7.33

adrenal gland:6.81

pancreas:6.82

breast:7.21

salivary:6.76

CAGE

uterus:3.63

placenta:3.27

prostate:3.51

ovary:3.70

testis:3.47

heart:3.34

muscle:3.67

esophagus:3.13

stomach:-

intestine:3.11

colon:3.22

liver/hepato:3.03

lung:3.07

bladder:3.55

kidney:3.00

pituitary:3.29

thyroid/parathyroid:3.41

adrenal gland:-

pancreas:3.69

breast:2.83

salivary:3.32

RNA-seq

uterus:-

placenta:-

prostate:3.56

ovary:3.89

testis:3.43

heart:2.43

muscle:4.24

esophagus:-

stomach:-

intestine:-

colon:3.08

liver/hepato:2.48

lung:2.78

bladder:-

kidney:3.08

pituitary:-

thyroid/parathyroid:3.53

adrenal gland:3.44

pancreas:-

breast:3.05

salivary:-

IDs

Refseq ID	NM_005652
Gene ID	7014
Unigene ID	-
Probe set ID	203611_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000132604
GTEx ID	ENSG00000132604

Orthologous Gene

Mouse[2]	NM_001083118, NM_009353
Rat [0]

Chromosomal Region

16q22.1 [69,389,464 - 69,419,859]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR009057	Homeodomain-like
IPR012287	Homeodomain-related
IPR017877	MYB-like
IPR001005	SANT, DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0001309	age-dependent telomere shortening
GO:0007049	cell cycle
GO:0032205	negative regulation of telomere maintenance
GO:0032214	negative regulation of telomere maintenance via semi-conservative replication
GO:0031848	protection from non-homologous end joining at telomere
GO:0070198	protein localization to telomere
GO:0016233	telomere capping
GO:0000723	telomere maintenance
GO:0007004	telomere maintenance via telomerase
GO:0010834	telomere maintenance via telomere shortening
GO:0031627	telomeric loop formation

Cellular Component

GO:0000781	chromosome, telomeric region
GO:0005737	cytoplasm
GO:0005794	Golgi apparatus
GO:0030870	Mre11 complex
GO:0000783	nuclear telomere cap complex
GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003682	chromatin binding
GO:0003691	double-stranded telomeric DNA binding
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0042803	protein homodimerization activity
GO:0042162	telomeric DNA binding

telomeric repeat binding factor 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function