transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

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Synonym

Transcription factor ERF-1, TFAP2C, Activating enhancer-binding protein 2 gamma, AP2-GAMMA, TFAP2G, hAP-2g, AP2-gamma, Transcription factor AP-2 gamma

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:28.80
GeneChip cerebrum:3.62 cerebellum:3.48 brain stem:3.66 corpus callosum/glia:3.70 pineal gland:- peripheral nerve:4.18 spine:3.80 retina:- eye:- artery/aorta:3.94 vein:3.73 lymphnode:4.19 peripheral blood:- spleen:3.71 thymus:3.68 bone marrow:3.79 adipose:4.54 bone:- skin:6.86
CAGE cerebrum:0.51 cerebellum:- brain stem:0.34 corpus callosum/glia:0.52 pineal gland:0.74 peripheral nerve:- spine:0.61 retina:- eye:- artery/aorta:1.48 vein:0.47 lymphnode:1.37 peripheral blood:- spleen:0 thymus:0.37 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:0.37 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.21 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.42 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:29.10 prostate:11.30 ovary:37.30 testis:4.30 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:5.43 placenta:7.73 prostate:6.12 ovary:4.36 testis:3.72 heart:3.74 muscle:4.13 esophagus:6.97 stomach:3.83 intestine:4.01 colon:3.95 liver/hepato:3.68 lung:4.25 bladder:- kidney:3.93 pituitary:3.96 thyroid/parathyroid:4.53 adrenal gland:3.61 pancreas:3.94 breast:7.75 salivary:6.88
CAGE uterus:2.56 placenta:4.26 prostate:2.25 ovary:0.52 testis:0.80 heart:0.42 muscle:0.46 esophagus:3.38 stomach:- intestine:0.27 colon:1.49     liver/hepato:0    lung:1.80 bladder:1.24 kidney:0.62 pituitary:0.50 thyroid/parathyroid:1.88 adrenal gland:- pancreas:0.94 breast:3.30 salivary:3.46
RNA-seq uterus:- placenta:- prostate:1.55 ovary:0.65 testis:1.29 heart:0.13 muscle:0.10 esophagus:- stomach:- intestine:- colon:1.64     liver/hepato:0.02        lung:1.40    bladder:- kidney:0.95 pituitary:- thyroid/parathyroid:2.25 adrenal gland:0.16 pancreas:- breast:3.75 salivary:-

Gene Information

IDs

Refseq ID NM_003222
Gene ID 7022
Unigene ID Hs.473152
Probe set ID 205286_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000087510
GTEx ID ENSG00000087510

Orthologous Gene

Mouse[6]  NM_001159696, NM_009335
Rat[1]  NM_201420, NM_009335

Chromosomal Region

20q13.31  [55,204,358  -  55,214,339]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7846046
7891714
8661133
9113991
11095974
11278550
11694877
11744733
11773066
11780052
11859873
12072434
12226108
12228234
12477932
12490322
12586840
12801994
12833450
14565844
15489334
15548692
15569994
15700319
16636674
16867219
17848411
17875680
17947476
18042070
18443366
19115315
19130459
19322201
19443578
19458056
19471022
19671168
19798054
20629094
21363924
21468029
21572391
21693764
21963094
21988832
22371483
22379092
22560121
22702469
22878616
22964634
23036739
23334330
24023917
24045439

Gene Ontology  (GO ID)

Biological Process

GO:0007267  cell-cell signaling
GO:0021987  cerebral cortex development
GO:0060598  dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
GO:0060750  epithelial cell proliferation involved in mammary gland duct elongation
GO:0021877  forebrain neuron fate commitment
GO:0030718  germ-line stem cell maintenance
GO:0001942  hair follicle development
GO:0003334  keratinocyte development
GO:0008584  male gonad development
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045682  regulation of epidermis development
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0048733  sebaceous gland development
GO:0035019  somatic stem cell maintenance
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0046983  protein dimerization activity
GO:0003700  transcription factor activity