nuclear receptor subfamily 2, group F, member 2

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Synonym

Apolipoprotein AI regulatory protein 1, COUP-TFII, COUP transcription factor 2, TFCOUP2, nuclear receptor subfamily 2, group F, member 2, NR2F2, MGC117452, COUPTFB, ARP-1, COUP-TF II, SVP40, COUP-TF2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.28 cerebellum:4.13 brain stem:5.09 corpus callosum/glia:3.88 pineal gland:- peripheral nerve:9.33 spine:6 retina:- eye:- artery/aorta:7.84 vein:8.47 lymphnode:7.45 peripheral blood:- spleen:9.44 thymus:5.32 bone marrow:3.84 adipose:8.26 bone:- skin:7.03
CAGE cerebrum:3.76 cerebellum:- brain stem:3.98 corpus callosum/glia:3.38 pineal gland:3.68 peripheral nerve:- spine:4.62 retina:- eye:- artery/aorta:5.39 vein:5.25 lymphnode:4.87 peripheral blood:- spleen:6.21 thymus:2.52 bone marrow:- adipose:5.37 bone:- skin:-
RNA-seq cerebrum:1.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.35 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:9.65 placenta:7.84 prostate:8.62 ovary:9.25 testis:7.21 heart:7.60 muscle:6.37 esophagus:6.54 stomach:8.56 intestine:7.67 colon:7.38 liver/hepato:7.44 lung:7.83 bladder:- kidney:8.58 pituitary:6.47 thyroid/parathyroid:7.63 adrenal gland:8.78 pancreas:6.31 breast:7.88 salivary:6
CAGE uterus:6.48 placenta:5.09 prostate:5.48 ovary:6.70 testis:5.50 heart:5.03 muscle:5.05 esophagus:5.39 stomach:- intestine:4.38 colon:5.12     liver/hepato:4.64    lung:5.55 bladder:5.56 kidney:5.73 pituitary:4.33 thyroid/parathyroid:4.94 adrenal gland:- pancreas:4.07 breast:6.49 salivary:3.82
RNA-seq uterus:- placenta:- prostate:4.39 ovary:6.24 testis:5.02 heart:2.19 muscle:2.92 esophagus:- stomach:- intestine:- colon:4.66     liver/hepato:2.97        lung:4.62    bladder:- kidney:4.76 pituitary:- thyroid/parathyroid:3.39 adrenal gland:5.03 pancreas:- breast:3.93 salivary:-

Gene Information

IDs

Refseq ID NM_001145156
Gene ID 7026
Unigene ID -
Probe set ID 209120_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000185551
GTEx ID ENSG00000185551

Orthologous Gene

Mouse[4]  NM_009697, NM_183261
Rat [0]  

Chromosomal Region

15q26.2  [96,869,157  -  96,883,492]

Gene Family (Interpro ID)

IPR000003  Retinoid X receptor
IPR001723  Steroid hormone receptor
IPR001728  Thyroid hormone receptor
IPR003068  Transcription factor COUP
IPR013088  Zinc finger, NHR/GATA-type
IPR001628  Zinc finger, nuclear hormone receptor-type

Link to Pubmed  (Pubmed ID)

1312668
1820218
1899293
8530078
8910285
9115274
9343308
9826778
10318855
10704340
10744719
11544252
12477932
12614160
12843196
14739255
15140878
15231748
15265774
15489334
15604093
15611122
15666827
16219912
17455195
17554300
18199540
18765665
18798693
18815287
19082449
19154418
19210544
19505873
19913121
20147377
20195529
20211142
20351309
20386594
20549515
20585627
20628086
21151097
21549307
21890473
21906983
21988832
22178710
22219177
22242598
22493443
22569225
22606236
22693611
22734039
22829776
23136034
23201680
23345397
23458092
23690307
23704310
23744056
23975195
24058409
24122412
24702954

Gene Ontology  (GO ID)

Biological Process

GO:0009952  anterior/posterior pattern formation
GO:0048514  blood vessel morphogenesis
GO:0009566  fertilization
GO:0030900  forebrain development
GO:0030522  intracellular receptor-mediated signaling pathway
GO:0060173  limb development
GO:0006629  lipid metabolic process
GO:0001893  maternal placenta development
GO:0045736  negative regulation of cyclin-dependent protein kinase activity
GO:0010596  negative regulation of endothelial cell migration
GO:0001937  negative regulation of endothelial cell proliferation
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0001764  neuron migration
GO:0060674  placenta blood vessel development
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0009956  radial pattern formation
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0060849  regulation of transcription involved in lymphatic endothelial cell fate commitment
GO:0032355  response to estradiol stimulus
GO:0007165  signal transduction
GO:0007519  skeletal muscle tissue development
GO:0060707  trophoblast giant cell differentiation

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0001972  retinoic acid binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding