transforming growth factor, beta 3

jump to detail


Transforming growth factor beta-3 precursor, TGF-beta-3, TGFbeta3, TGF beta(3), transforming growth factor, beta 3, TGFbeta 3, TGF beta3, TGFB3, TGFb3, FLJ16571, ARVD, TGF beta 3, TGF-beta3

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:47 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:37.80 thymus:12.90 bone marrow:19.70 adipose:40.30 bone:12.80 skin:9.60
GeneChip cerebrum:6.83 cerebellum:6.33 brain stem:6.78 corpus callosum/glia:7.21 pineal gland:- peripheral nerve:6.19 spine:6.89 retina:- eye:- artery/aorta:7.15 vein:8.33 lymphnode:6.55 peripheral blood:- spleen:6 thymus:5.73 bone marrow:6.13 adipose:6.87 bone:- skin:6.13
CAGE cerebrum:2.26 cerebellum:- brain stem:3.04 corpus callosum/glia:3.25 pineal gland:1.52 peripheral nerve:- spine:2.69 retina:- eye:- artery/aorta:3.16 vein:2.35 lymphnode:2.32 peripheral blood:- spleen:0.80 thymus:1.36 bone marrow:- adipose:1.93 bone:- skin:-
RNA-seq cerebrum:2.88 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.85 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.34 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:54.60 prostate:169 ovary:74.50 testis:8.70 heart:76.60 muscle:- esophagus:- stomach:21.20 intestine:- colon:25.40     liver/hepato:21.10        lung:24.40    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:53.30 breast:27.90 salivary:-
GeneChip uterus:7.01 placenta:6.97 prostate:7.44 ovary:6.24 testis:5.87 heart:7.03 muscle:6.90 esophagus:6.15 stomach:6.64 intestine:6.60 colon:6.81 liver/hepato:6.25 lung:6.62 bladder:- kidney:6.20 pituitary:6.49 thyroid/parathyroid:6.33 adrenal gland:6.96 pancreas:6.85 breast:6.82 salivary:6.25
CAGE uterus:3.00 placenta:3.19 prostate:4.16 ovary:2.39 testis:1.95 heart:3.00 muscle:2.59 esophagus:1.89 stomach:- intestine:1.29 colon:1.29     liver/hepato:3.09    lung:2.13 bladder:3.35 kidney:1.99 pituitary:1.82 thyroid/parathyroid:1.78 adrenal gland:- pancreas:1.98 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:3.54 ovary:2.73 testis:4.12 heart:2.47 muscle:4.26 esophagus:- stomach:- intestine:- colon:3.13     liver/hepato:1.55        lung:5.01    bladder:- kidney:2.32 pituitary:- thyroid/parathyroid:2.95 adrenal gland:4.22 pancreas:- breast:2.62 salivary:-


Refseq ID NM_003239
Gene ID 7043
Unigene ID Hs.592317
Probe set ID 209747_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000119699
GTEx ID ENSG00000119699

Orthologous Gene

Mouse[1]  NM_009368
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0007568  aging
GO:0007596  blood coagulation
GO:0016049  cell growth
GO:0045216  cell-cell junction organization
GO:0070483  detection of hypoxia
GO:0048702  embryonic neurocranium morphogenesis
GO:0030198  extracellular matrix organization
GO:0060325  face morphogenesis
GO:0007565  female pregnancy
GO:0060364  frontal suture morphogenesis
GO:0048565  gut development
GO:0001701  in utero embryonic development
GO:0006917  induction of apoptosis
GO:0048839  inner ear development
GO:0048286  lung alveolus development
GO:0030879  mammary gland development
GO:0022601  menstrual cycle phase
GO:0008285  negative regulation of cell proliferation
GO:0008156  negative regulation of DNA replication
GO:0010936  negative regulation of macrophage cytokine production
GO:0043524  negative regulation of neuron apoptosis
GO:0030512  negative regulation of transforming growth factor beta receptor signaling pathway
GO:0042476  odontogenesis
GO:0043932  ossification involved in bone remodeling
GO:0060021  palate development
GO:0030168  platelet activation
GO:0002576  platelet degranulation
GO:0043065  positive regulation of apoptosis
GO:0030501  positive regulation of bone mineralization
GO:0051781  positive regulation of cell division
GO:0032967  positive regulation of collagen biosynthetic process
GO:0045740  positive regulation of DNA replication
GO:0010718  positive regulation of epithelial to mesenchymal transition
GO:0051491  positive regulation of filopodium assembly
GO:0010862  positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0050714  positive regulation of protein secretion
GO:0060391  positive regulation of SMAD protein nuclear translocation
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0043627  response to estrogen stimulus
GO:0001666  response to hypoxia
GO:0034616  response to laminar fluid shear stress
GO:0032570  response to progesterone stimulus
GO:0007435  salivary gland morphogenesis
GO:0007184  SMAD protein nuclear translocation
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0043025  cell soma
GO:0009986  cell surface
GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0031093  platelet alpha granule lumen
GO:0030315  T-tubule

Molecular Function

GO:0008083  growth factor activity
GO:0042802  identical protein binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0050431  transforming growth factor beta binding
GO:0034713  type I transforming growth factor beta receptor binding
GO:0005114  type II transforming growth factor beta receptor binding