TIMP metallopeptidase inhibitor 3

Synonym

Protein MIG-5, Metalloproteinase inhibitor 3 precursor, TIMP3, TIMP-3, K222TA2, Tissue inhibitor of metalloproteinases 3, SFD, HSMRK222, K222

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:7.29

cerebellum:6.35

brain stem:7.73

corpus callosum/glia:7.06

pineal gland:-

peripheral nerve:10.16

spine:8.01

retina:-

eye:-

artery/aorta:9.97

vein:10.23

lymphnode:7.90

peripheral blood:-

spleen:9.34

thymus:7.18

bone marrow:5.99

adipose:10.49

bone:-

skin:9.33

CAGE

cerebrum:4.57

cerebellum:-

brain stem:4.80

corpus callosum/glia:5.02

pineal gland:5.02

peripheral nerve:-

spine:4.77

retina:-

eye:-

artery/aorta:6.39

vein:6.41

lymphnode:5.30

peripheral blood:-

spleen:5.99

thymus:2.66

bone marrow:-

adipose:7.39

bone:-

skin:-

RNA-seq

cerebrum:5.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:7.39

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:9.38

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:9.68

placenta:10.57

prostate:9.30

ovary:8.63

testis:8.10

heart:9.72

muscle:8.29

esophagus:8.81

stomach:9.34

intestine:8.64

colon:8.84

liver/hepato:7.30

lung:10.79

bladder:-

kidney:9.23

pituitary:8.22

thyroid/parathyroid:9.80

adrenal gland:10.08

pancreas:8.29

breast:9.96

salivary:8.60

CAGE

uterus:6.67

placenta:8.30

prostate:6.25

ovary:5.66

testis:5.91

heart:6.66

muscle:5.47

esophagus:6.15

stomach:-

intestine:4.87

colon:5.49

liver/hepato:4.65

lung:7.24

bladder:6.08

kidney:6.38

pituitary:5.02

thyroid/parathyroid:6.02

adrenal gland:-

pancreas:4.43

breast:7.13

salivary:5.34

RNA-seq

uterus:-

placenta:-

prostate:7.25

ovary:5.41

testis:7.95

heart:7.16

muscle:5.76

esophagus:-

stomach:-

intestine:-

colon:7.88

liver/hepato:5.12

lung:9.54

bladder:-

kidney:7.95

pituitary:-

thyroid/parathyroid:7.83

adrenal gland:8.08

pancreas:-

breast:8.21

salivary:-

IDs

Refseq ID	NM_000362
Gene ID	7078
Unigene ID	-
Probe set ID	201150_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000100234
GTEx ID	ENSG00000100234

Orthologous Gene

Mouse[4]	NM_011595
Rat[1]	NM_012886

Chromosomal Region

22q12.3 [33,197,687 - 33,259,030]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001134	Netrin domain
IPR001820	Proteinase inhibitor I35, tissue inhibitor of metalloproteinase
IPR008993	TIMP-like, OB-fold

Gene Ontology (GO ID)

Biological Process

GO:0071310	cellular response to organic substance
GO:0051045	negative regulation of membrane protein ectodomain proteolysis
GO:0007601	visual perception

Cellular Component

GO:0005604	basement membrane
GO:0031012	extracellular matrix

Molecular Function

GO:0046872	metal ion binding
GO:0008191	metalloendopeptidase inhibitor activity
GO:0005515	protein binding

TIMP metallopeptidase inhibitor 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function