tropomyosin 1 (alpha)

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Synonym

TPM1, Alpha-tropomyosin, TPM1-alpha, HTM-alpha, TMSA, tropomyosin 1 (alpha), TPM1-kappa, Tropomyosin 1 alpha chain

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:115

cerebellum:37.80

brain stem:-

corpus callosum/glia:204.10

pineal gland:-

peripheral nerve:490.80

spine:336.90

retina:237.30

eye:440.80

artery/aorta:1348.90

vein:1799.50

lymphnode:40.40

peripheral blood:-

spleen:75.60

thymus:25.80

bone marrow:216.50

adipose:1169.70

bone:115.20

skin:196.80

GeneChip

cerebrum:7.24

cerebellum:7.49

brain stem:7.20

corpus callosum/glia:6.37

pineal gland:-

peripheral nerve:8.80

spine:7.72

retina:-

eye:-

artery/aorta:11.32

vein:11.65

lymphnode:8.22

peripheral blood:-

spleen:8.50

thymus:6.39

bone marrow:7.17

adipose:9.83

bone:-

skin:9.56

CAGE

cerebrum:4.44

cerebellum:-

brain stem:4.12

corpus callosum/glia:3.97

pineal gland:4.31

peripheral nerve:-

spine:4.28

retina:-

eye:-

artery/aorta:6.66

vein:5.92

lymphnode:4.48

peripheral blood:-

spleen:4.82

thymus:2.57

bone marrow:-

adipose:5.85

bone:-

skin:-

RNA-seq

cerebrum:3.59

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.42

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.50

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:628.80

placenta:364.30

prostate:664.60

ovary:298.10

testis:73.50

heart:3129.10

muscle:4038.20

esophagus:2399.70

stomach:403.60

intestine:583.20

colon:483.30

liver/hepato:168.90

lung:219.90

bladder:753.70

kidney:280.70

pituitary:232

thyroid/parathyroid:327.50

adrenal gland:50.80

pancreas:177.80

breast:176.60

salivary:656.80

GeneChip

uterus:11.18

placenta:9.69

prostate:11.52

ovary:10.58

testis:7.34

heart:8.75

muscle:7.65

esophagus:8.81

stomach:11.25

intestine:10.89

colon:11.02

liver/hepato:7.74

lung:9.33

bladder:-

kidney:9.17

pituitary:7.40

thyroid/parathyroid:9.02

adrenal gland:9.16

pancreas:10.95

breast:10.61

salivary:9.41

CAGE

uterus:7.00

placenta:5.72

prostate:7.25

ovary:6.22

testis:4.91

heart:8.53

muscle:7.88

esophagus:7.73

stomach:-

intestine:6.56

colon:6.83

liver/hepato:4.08

lung:4.94

bladder:8.20

kidney:5.58

pituitary:3.93

thyroid/parathyroid:4.94

adrenal gland:-

pancreas:6.22

breast:5.39

salivary:5.04

RNA-seq

uterus:-

placenta:-

prostate:5.99

ovary:6.00

testis:5.18

heart:0.00

muscle:3.98

esophagus:-

stomach:-

intestine:-

colon:5.75

liver/hepato:1.50

lung:4.90

bladder:-

kidney:5.32

pituitary:-

thyroid/parathyroid:4.71

adrenal gland:4.91

pancreas:-

breast:5.75

salivary:-

IDs

Refseq ID	NM_001018004
Gene ID	7168
Unigene ID	Hs.133892
Probe set ID	210986_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000140416
GTEx ID	ENSG00000140416

Orthologous Gene

Mouse[13]	NM_001164248, NM_001164249, NM_001164250, NM_001164251, NM_001164252, NM_001164253, NM_001164254, NM_001164255, NM_001164256, NM_024427
Rat [0]

Chromosomal Region

15q22.2 [63,334,831 - 63,364,111]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0060048	cardiac muscle contraction
GO:0006928	cellular component movement
GO:0034614	cellular response to reactive oxygen species
GO:0007010	cytoskeleton organization
GO:0001701	in utero embryonic development
GO:0006936	muscle contraction
GO:0030049	muscle filament sliding
GO:0030336	negative regulation of cell migration
GO:0032781	positive regulation of ATPase activity
GO:0045785	positive regulation of cell adhesion
GO:0003065	positive regulation of heart rate by epinephrine
GO:0051496	positive regulation of stress fiber formation
GO:0008016	regulation of heart contraction
GO:0006937	regulation of muscle contraction
GO:0031529	ruffle organization
GO:0045214	sarcomere organization
GO:0055010	ventricular cardiac muscle tissue morphogenesis
GO:0042060	wound healing

Cellular Component

GO:0015629	actin cytoskeleton
GO:0032059	bleb
GO:0005737	cytoplasm
GO:0005856	cytoskeleton
GO:0005829	cytosol
GO:0031941	filamentous actin
GO:0005862	muscle thin filament tropomyosin
GO:0032587	ruffle membrane
GO:0030017	sarcomere
GO:0001725	stress fiber

Molecular Function

GO:0003779	actin binding
GO:0008092	cytoskeletal protein binding
GO:0005200	structural constituent of cytoskeleton
GO:0008307	structural constituent of muscle

tropomyosin 1 (alpha)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function