translocated promoter region (to activated MET oncogene)

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Synonym

TPR, Nucleoprotein TPR

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:50.40 brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:30.70 spine:112.30 retina:- eye:58.80 artery/aorta:30 vein:66.60 lymphnode:161.80 peripheral blood:18.20 spleen:- thymus:90.20 bone marrow:59 adipose:- bone:115.20 skin:192
GeneChip cerebrum:8.12 cerebellum:8.17 brain stem:8 corpus callosum/glia:8.59 pineal gland:- peripheral nerve:8.58 spine:8.10 retina:- eye:- artery/aorta:8.59 vein:8.59 lymphnode:9.24 peripheral blood:- spleen:9.21 thymus:9.33 bone marrow:7.91 adipose:8.39 bone:- skin:7.68
CAGE cerebrum:3.64 cerebellum:- brain stem:3.67 corpus callosum/glia:3.08 pineal gland:4.24 peripheral nerve:- spine:3.93 retina:- eye:- artery/aorta:3.40 vein:3.83 lymphnode:3.55 peripheral blood:- spleen:4.22 thymus:4.47 bone marrow:- adipose:4.01 bone:- skin:-
RNA-seq cerebrum:3.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.92 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.73 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:69.20 prostate:45.10 ovary:37.30 testis:60.60 heart:63.90 muscle:80.40 esophagus:685.60 stomach:382.40 intestine:64.80 colon:84.80     liver/hepato:105.60        lung:73.30    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:80 breast:130.10 salivary:-
GeneChip uterus:9.05 placenta:8.43 prostate:8.75 ovary:9.24 testis:9.93 heart:8.49 muscle:7.90 esophagus:8.58 stomach:8.51 intestine:7.51 colon:6.89 liver/hepato:8.56 lung:8.70 bladder:- kidney:7.61 pituitary:8.38 thyroid/parathyroid:8.51 adrenal gland:9.11 pancreas:7.03 breast:8.52 salivary:7.46
CAGE uterus:3.79 placenta:4.29 prostate:4.14 ovary:4.19 testis:4.67 heart:4.26 muscle:4.43 esophagus:3.95 stomach:- intestine:3.88 colon:3.62     liver/hepato:3.83    lung:3.93 bladder:4.20 kidney:3.88 pituitary:4.33 thyroid/parathyroid:3.82 adrenal gland:- pancreas:2.76 breast:3.92 salivary:2.50
RNA-seq uterus:- placenta:- prostate:3.70 ovary:4.17 testis:5.13 heart:3.35 muscle:3.60 esophagus:- stomach:- intestine:- colon:3.49     liver/hepato:2.28        lung:3.18    bladder:- kidney:3.32 pituitary:- thyroid/parathyroid:4.48 adrenal gland:3.84 pancreas:- breast:3.39 salivary:-

Gene Information

IDs

Refseq ID NM_003292
Gene ID 7175
Unigene ID Hs.279640
Probe set ID 201730_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000047410
GTEx ID ENSG00000047410

Orthologous Gene

Mouse[4]  NM_133780
Rat [0]  

Chromosomal Region

1q31.1  [186,282,954  -  186,344,825]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1437155
1532241
1549355
1611909
3277171
3387099
3821733
7798308
7851906
9024684
9828100
9864356
10601273
10708513
11248057
11514627
11839768
11896612
11952838
12228227
12477932
12513910
12594221
12802065
14702039
15229283
15302935
15635413
15654337
16051665
16964243
17081983
17098863
17643375
17897941
18029348
18663750
18794356
18981471
19273613
19394292
19460752
19471022
19596686
19738201
20237496
20360068
20407419
20479123
20936779
21139048
21282530
21613532
21628590
21693764
21811608
21890473
21906983
22053931
22145905
22253824
22412018
22586326
22619110
22623428
22939629
23000965
23110726
23170199
23402259
23649804
23752268
24250222
24344181
24457600
24581499
24583282
24639526
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0005975  carbohydrate metabolic process
GO:0051301  cell division
GO:0034605  cellular response to heat
GO:0019221  cytokine-mediated signaling pathway
GO:0015758  glucose transport
GO:0008645  hexose transport
GO:0007067  mitosis
GO:0000278  mitotic cell cycle
GO:0007094  mitotic cell cycle spindle assembly checkpoint
GO:0007077  mitotic nuclear envelope disassembly
GO:0031990  mRNA export from nucleus during heat stress
GO:0046832  negative regulation of RNA export from nucleus
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045947  negative regulation of translational initiation
GO:0043578  nuclear matrix organization
GO:0051292  nuclear pore complex assembly
GO:0006999  nuclear pore organization
GO:0000189  nuclear translocation of MAPK
GO:0031453  positive regulation of heterochromatin formation
GO:0046827  positive regulation of protein export from nucleus
GO:0042307  positive regulation of protein import into nucleus
GO:0006611  protein export from nucleus
GO:0006606  protein import into nucleus
GO:0010827  regulation of glucose transport
GO:0010965  regulation of mitotic sister chromatid separation
GO:0010793  regulation of mRNA export from nucleus
GO:0046825  regulation of protein export from nucleus
GO:0042306  regulation of protein import into nucleus
GO:0031647  regulation of protein stability
GO:0070849  response to epidermal growth factor stimulus
GO:0006405  RNA export from nucleus
GO:0006404  RNA import into nucleus
GO:0006434  seryl-tRNA aminoacylation
GO:0055085  transmembrane transport
GO:0016032  viral reproduction

Cellular Component

GO:0005737  cytoplasm
GO:0005868  cytoplasmic dynein complex
GO:0019898  extrinsic to membrane
GO:0000776  kinetochore
GO:0005635  nuclear envelope
GO:0042405  nuclear inclusion body
GO:0031965  nuclear membrane
GO:0034399  nuclear periphery
GO:0005643  nuclear pore
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0003682  chromatin binding
GO:0070840  dynein complex binding
GO:0031072  heat shock protein binding
GO:0051019  mitogen-activated protein kinase binding
GO:0003729  mRNA binding
GO:0005487  nucleocytoplasmic transporter activity
GO:0043495  protein anchor
GO:0005515  protein binding
GO:0042803  protein homodimerization activity
GO:0004828  serine-tRNA ligase activity
GO:0005215  transporter activity
GO:0015631  tubulin binding