heat shock protein 90kDa beta (Grp94), member 1

Synonym

HSP90B1, GRP94, TRA1, tumor rejection antigen (gp96) 1, heat shock protein 90kDa beta (Grp94), member 1, 94 kDa glucose-regulated protein, ECGP, GP96, Endoplasmin precursor, Tumor rejection antigen 1, Heat shock protein 90 kDa beta member 1, gp96 homolog

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:285.60

cerebellum:151.10

brain stem:-

corpus callosum/glia:758.20

pineal gland:-

peripheral nerve:644.10

spine:224.60

retina:355.90

eye:229.20

artery/aorta:959.20

vein:466.50

lymphnode:262.90

peripheral blood:528.30

spleen:813

thymus:296.30

bone marrow:275.50

adipose:443.70

bone:627

skin:705.60

GeneChip

cerebrum:8.93

cerebellum:8.16

brain stem:8.94

corpus callosum/glia:9.34

pineal gland:-

peripheral nerve:9.62

spine:9.38

retina:-

eye:-

artery/aorta:9.80

vein:9.61

lymphnode:9.95

peripheral blood:-

spleen:9.74

thymus:9.78

bone marrow:9.55

adipose:9.65

bone:-

skin:8.96

CAGE

cerebrum:5.25

cerebellum:-

brain stem:5.40

corpus callosum/glia:5.11

pineal gland:5.92

peripheral nerve:-

spine:5.62

retina:-

eye:-

artery/aorta:5.60

vein:5.50

lymphnode:5.89

peripheral blood:-

spleen:6.68

thymus:5.82

bone marrow:-

adipose:5.87

bone:-

skin:-

RNA-seq

cerebrum:6.41

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:8.15

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:6.92

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:592.40

placenta:601.10

prostate:461.80

ovary:409.90

testis:363.40

heart:370.40

muscle:180.80

esophagus:-

stomach:446.10

intestine:356.40

colon:619

liver/hepato:548.90

lung:576.70

bladder:1004.90

kidney:270.30

pituitary:463.90

thyroid/parathyroid:491.20

adrenal gland:355.50

pancreas:426.80

breast:901.40

salivary:328.40

GeneChip

uterus:10.18

placenta:10.62

prostate:10.57

ovary:10.38

testis:9.52

heart:9.61

muscle:7.33

esophagus:9.16

stomach:10.19

intestine:9.65

colon:8.72

liver/hepato:10.30

lung:9.88

bladder:-

kidney:9.15

pituitary:10.69

thyroid/parathyroid:11.31

adrenal gland:10.42

pancreas:10.43

breast:9.28

salivary:9.38

CAGE

uterus:5.83

placenta:6.92

prostate:6.11

ovary:6.18

testis:5.57

heart:6.10

muscle:5.40

esophagus:5.74

stomach:-

intestine:6.17

colon:5.64

liver/hepato:7.81

lung:5.90

bladder:6.40

kidney:6.46

pituitary:6.38

thyroid/parathyroid:7.96

adrenal gland:-

pancreas:6.67

breast:6.34

salivary:5.68

RNA-seq

uterus:-

placenta:-

prostate:7.24

ovary:7.86

testis:7.73

heart:6.25

muscle:4.98

esophagus:-

stomach:-

intestine:-

colon:8.22

liver/hepato:8.91

lung:7.84

bladder:-

kidney:8.36

pituitary:-

thyroid/parathyroid:9.34

adrenal gland:8.13

pancreas:-

breast:7.08

salivary:-

IDs

Refseq ID	NM_003299
Gene ID	7184
Unigene ID	Hs.192374
Probe set ID	200599_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000166598
GTEx ID	ENSG00000166598

Orthologous Gene

Mouse[2]	NM_011631
Rat [0]

Chromosomal Region

12q23.3 [104,323,885 - 104,347,423]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR003594	ATPase-like, ATP-binding domain
IPR001404	Chaperone protein htpG
IPR020575	Heat shock protein Hsp90, N-terminal

Gene Ontology (GO ID)

Biological Process

GO:0031247	actin rod formation
GO:0006987	activation of signaling protein activity involved in unfolded protein response
GO:0044267	cellular protein metabolic process
GO:0071318	cellular response to ATP
GO:0030968	endoplasmic reticulum unfolded protein response
GO:0030433	ER-associated protein catabolic process
GO:0045087	innate immune response
GO:0043066	negative regulation of apoptosis
GO:0006457	protein folding
GO:0015031	protein transport
GO:0043666	regulation of phosphoprotein phosphatase activity
GO:0001666	response to hypoxia
GO:0051208	sequestering of calcium ion
GO:0002224	toll-like receptor signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0005783	endoplasmic reticulum
GO:0005788	endoplasmic reticulum lumen
GO:0005789	endoplasmic reticulum membrane
GO:0005576	extracellular region
GO:0042470	melanosome
GO:0030496	midbody
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0005509	calcium ion binding
GO:0050750	low-density lipoprotein receptor binding
GO:0005515	protein binding
GO:0019903	protein phosphatase binding
GO:0003723	RNA binding
GO:0051082	unfolded protein binding
GO:0046790	virion binding

heat shock protein 90kDa beta (Grp94), member 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function