TNF receptor-associated factor 3

Synonym

CD40-binding protein, TRAF3, CD40bp, CAP-1, CD40BP, TNF receptor-associated factor 3, CRAF1, CD40 receptor-associated factor 1, LMP1-associated protein

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:15.40

cerebellum:-

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:58.80

artery/aorta:-

vein:-

lymphnode:91

peripheral blood:-

spleen:75.60

thymus:12.90

bone marrow:59

adipose:-

bone:-

skin:33.60

GeneChip

cerebrum:5.49

cerebellum:5.38

brain stem:5.56

corpus callosum/glia:5.37

pineal gland:-

peripheral nerve:4.97

spine:5.23

retina:-

eye:-

artery/aorta:4.96

vein:5.54

lymphnode:5.50

peripheral blood:-

spleen:5.12

thymus:4.97

bone marrow:5.51

adipose:5.29

bone:-

skin:4.93

CAGE

cerebrum:2.15

cerebellum:-

brain stem:2.19

corpus callosum/glia:2.26

pineal gland:1.94

peripheral nerve:-

spine:2.17

retina:-

eye:-

artery/aorta:2.51

vein:2.89

lymphnode:3.21

peripheral blood:-

spleen:2.64

thymus:2.25

bone marrow:-

adipose:1.69

bone:-

skin:-

RNA-seq

cerebrum:0.65

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.29

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.93

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:63.80

placenta:18.20

prostate:22.50

ovary:37.30

testis:21.60

heart:-

muscle:-

esophagus:-

stomach:85

intestine:-

colon:93.30

liver/hepato:10.60

lung:29.30

bladder:125.60

kidney:20.80

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:55.80

salivary:-

GeneChip

uterus:4.99

placenta:5.08

prostate:4.78

ovary:5.17

testis:5.34

heart:5.36

muscle:5.25

esophagus:5.13

stomach:5.29

intestine:5.35

colon:5.67

liver/hepato:5.43

lung:5.10

bladder:-

kidney:5.29

pituitary:5.29

thyroid/parathyroid:4.72

adrenal gland:5.18

pancreas:5.56

breast:4.88

salivary:5.13

CAGE

uterus:1.87

placenta:1.98

prostate:1.83

ovary:1.73

testis:2.27

heart:2.17

muscle:1.08

esophagus:1.56

stomach:-

intestine:2.05

colon:2.33

liver/hepato:1.69

lung:2.26

bladder:2.16

kidney:1.70

pituitary:2.01

thyroid/parathyroid:1.38

adrenal gland:-

pancreas:1.74

breast:2.27

salivary:1.75

RNA-seq

uterus:-

placenta:-

prostate:0.46

ovary:1.45

testis:0.44

heart:0.46

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.71

lung:1.43

bladder:-

kidney:0.70

pituitary:-

thyroid/parathyroid:0.16

adrenal gland:1.43

pancreas:-

breast:1.52

salivary:-

IDs

Refseq ID	NM_003300
Gene ID	7187
Unigene ID	Hs.510528
Probe set ID	208315_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000131323
GTEx ID	ENSG00000131323

Orthologous Gene

Mouse[4]	NM_001048206, NM_011632
Rat[1]	NM_001108724, NM_011632

Chromosomal Region

14q32.32 [103,243,816 - 103,372,628]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_229 [5,001 - 139,022]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002083	MATH
IPR012227	TNF receptor-associated factor TRAF
IPR008974	TRAF-like

Gene Ontology (GO ID)

Biological Process

GO:0006915	apoptosis
GO:0006917	induction of apoptosis
GO:0045087	innate immune response
GO:0002756	MyD88-independent toll-like receptor signaling pathway
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0032480	negative regulation of type I interferon production
GO:0001817	regulation of cytokine production
GO:0050688	regulation of defense response to virus
GO:0032648	regulation of interferon-beta production
GO:0030162	regulation of proteolysis
GO:0007165	signal transduction
GO:0008063	Toll signaling pathway
GO:0034138	toll-like receptor 3 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0033209	tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005829	cytosol
GO:0005768	endosome
GO:0009898	internal side of plasma membrane
GO:0005739	mitochondrion

Molecular Function

GO:0005515	protein binding
GO:0019901	protein kinase binding
GO:0004871	signal transducer activity
GO:0031996	thioesterase binding
GO:0031625	ubiquitin protein ligase binding
GO:0004842	ubiquitin-protein ligase activity
GO:0008270	zinc ion binding

TNF receptor-associated factor 3

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function