tyrosinase (oculocutaneous albinism IA)

Synonym

TYR, LB24-AB, tyrosinase (oculocutaneous albinism IA), OCAIA, SK29-AB, Tumor rejection antigen AB, Tyrosinase precursor, OCA1A, Monophenol monooxygenase

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:58.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:115.20

GeneChip

cerebrum:5.77

cerebellum:5.67

brain stem:5.68

corpus callosum/glia:5.65

pineal gland:-

peripheral nerve:5.69

spine:5.78

retina:-

eye:-

artery/aorta:5.87

vein:5.66

lymphnode:5.49

peripheral blood:-

spleen:5.32

thymus:5.48

bone marrow:5.83

adipose:5.82

bone:-

skin:6.52

CAGE

cerebrum:0.00

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0.22

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0.06

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.02

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:20.10

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:5.57

placenta:5.65

prostate:5.52

ovary:5.45

testis:6.05

heart:5.87

muscle:5.75

esophagus:5.87

stomach:5.65

intestine:5.62

colon:5.69

liver/hepato:5.81

lung:5.47

bladder:-

kidney:5.82

pituitary:5.74

thyroid/parathyroid:5.48

adrenal gland:5.69

pancreas:6.04

breast:5.78

salivary:5.71

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0

heart:0

muscle:0

esophagus:0

stomach:-

intestine:0

colon:0

liver/hepato:0

lung:0

bladder:0

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0

ovary:0

testis:0.20

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0

liver/hepato:0

lung:0

bladder:-

kidney:0

pituitary:-

thyroid/parathyroid:0

adrenal gland:0.02

pancreas:-

breast:0

salivary:-

IDs

Refseq ID	NM_000372
Gene ID	7299
Unigene ID	Hs.503555
Probe set ID	206630_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000077498
GTEx ID	ENSG00000077498

Orthologous Gene

Mouse[3]	NM_011661
Rat[1]	NM_001107535

Chromosomal Region

11q14.3 [88,910,620 - 89,028,908]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR008922	Di-copper centre-containing
IPR002227	Tyrosinase

GO:0008283	cell proliferation
GO:0006726	eye pigment biosynthetic process
GO:0006583	melanin biosynthetic process from tyrosine
GO:0048538	thymus development
GO:0007601	visual perception

GO:0005737	cytoplasm
GO:0005798	Golgi-associated vesicle
GO:0016021	integral to membrane
GO:0005764	lysosome
GO:0042470	melanosome
GO:0033162	melanosome membrane
GO:0048471	perinuclear region of cytoplasm

GO:0005507	copper ion binding
GO:0004503	monophenol monooxygenase activity
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0042803	protein homodimerization activity

tyrosinase (oculocutaneous albinism IA)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function