ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)

Synonym

Ubiquitin carrier protein N, Bendless-like ubiquitin-conjugating enzyme, MGC8489, BLU, Ubiquitin-conjugating enzyme E2 N, MGC131857, UbcH-ben, Ubiquitin-protein ligase N, UBC13, Ubc13, UBE2N

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:225.20

cerebellum:63

brain stem:-

corpus callosum/glia:145.80

pineal gland:148.30

peripheral nerve:61.30

spine:-

retina:237.30

eye:82.30

artery/aorta:60

vein:133.30

lymphnode:50.60

peripheral blood:54.70

spleen:75.60

thymus:90.20

bone marrow:118.10

adipose:80.70

bone:38.40

skin:144

GeneChip

cerebrum:7.51

cerebellum:7.73

brain stem:7.71

corpus callosum/glia:6.44

pineal gland:-

peripheral nerve:7.61

spine:7.33

retina:-

eye:-

artery/aorta:6.24

vein:6.49

lymphnode:6.53

peripheral blood:-

spleen:6.57

thymus:6.78

bone marrow:5.79

adipose:6.43

bone:-

skin:6.21

CAGE

cerebrum:4.84

cerebellum:-

brain stem:4.52

corpus callosum/glia:4.08

pineal gland:4.77

peripheral nerve:-

spine:4.36

retina:-

eye:-

artery/aorta:4.45

vein:4.25

lymphnode:4.48

peripheral blood:-

spleen:4.32

thymus:4.61

bone marrow:-

adipose:4.14

bone:-

skin:-

RNA-seq

cerebrum:5.36

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:4.80

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:4.43

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:109.40

placenta:43.70

prostate:90.10

ovary:-

testis:134.10

heart:102.20

muscle:100.50

esophagus:-

stomach:63.70

intestine:162

colon:93.30

liver/hepato:31.70

lung:136.90

bladder:251.20

kidney:187.10

pituitary:463.90

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:88.90

breast:65.10

salivary:-

GeneChip

uterus:6.84

placenta:6.29

prostate:7.34

ovary:6.86

testis:7.28

heart:6.50

muscle:7.05

esophagus:6.23

stomach:6.38

intestine:6.50

colon:6.74

liver/hepato:5.92

lung:6.40

bladder:-

kidney:6.70

pituitary:6.38

thyroid/parathyroid:6.40

adrenal gland:6.22

pancreas:5.71

breast:6.73

salivary:6.19

CAGE

uterus:4.13

placenta:4.19

prostate:4.09

ovary:4.22

testis:5.55

heart:4.55

muscle:4.56

esophagus:4.38

stomach:-

intestine:3.99

colon:4.20

liver/hepato:4.04

lung:4.20

bladder:4.14

kidney:4.28

pituitary:4.25

thyroid/parathyroid:3.96

adrenal gland:-

pancreas:4.09

breast:4.37

salivary:4.06

RNA-seq

uterus:-

placenta:-

prostate:4.74

ovary:5.06

testis:6.14

heart:4.29

muscle:4.13

esophagus:-

stomach:-

intestine:-

colon:4.86

liver/hepato:3.94

lung:4.58

bladder:-

kidney:5.02

pituitary:-

thyroid/parathyroid:4.68

adrenal gland:5.07

pancreas:-

breast:4.78

salivary:-

IDs

Refseq ID	NM_003348
Gene ID	7334
Unigene ID	Hs.524630
Probe set ID	212751_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000177889
GTEx ID	ENSG00000177889

Orthologous Gene

Mouse[1]	NM_080560
Rat[1]	NM_080560

Chromosomal Region

12q22 [93,799,449 - 93,836,038]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000608	Ubiquitin-conjugating enzyme, E2
IPR016135	Ubiquitin-conjugating enzyme/RWD-like

Gene Ontology (GO ID)

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0000729	DNA double-strand break processing
GO:0000724	double-strand break repair via homologous recombination
GO:0016574	histone ubiquitination
GO:0045087	innate immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway
GO:0045739	positive regulation of DNA repair
GO:0031058	positive regulation of histone modification
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051443	positive regulation of ubiquitin-protein ligase activity
GO:0006301	postreplication repair
GO:0070534	protein K63-linked ubiquitination
GO:0006464	protein modification process
GO:0016567	protein ubiquitination
GO:0006508	proteolysis
GO:0006282	regulation of DNA repair
GO:0033182	regulation of histone ubiquitination
GO:0050852	T cell receptor signaling pathway
GO:0034166	toll-like receptor 10 signaling pathway
GO:0034134	toll-like receptor 2 signaling pathway
GO:0034142	toll-like receptor 4 signaling pathway
GO:0034146	toll-like receptor 5 signaling pathway
GO:0034162	toll-like receptor 9 signaling pathway
GO:0002224	toll-like receptor signaling pathway
GO:0006511	ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005634	nucleus
GO:0031372	UBC13-MMS2 complex
GO:0000151	ubiquitin ligase complex

Molecular Function

GO:0005524	ATP binding
GO:0005515	protein binding
GO:0043130	ubiquitin binding
GO:0004842	ubiquitin-protein ligase activity

ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function