ubiquitin-conjugating enzyme E2 variant 2

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Synonym

Enterocyte differentiation-promoting factor, EDPF-1, EDAF-1, Vitamin D3-inducible protein, EDPF1, DDVit 1, Ubiquitin-conjugating enzyme E2 variant 2, DDVit-1, ubiquitin-conjugating enzyme E2 variant 2, MMS2, UEV2, DDVIT1, UBE2V2, UEV-2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:180.10 cerebellum:100.80 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:92 spine:- retina:- eye:64.60 artery/aorta:60 vein:- lymphnode:141.50 peripheral blood:54.70 spleen:- thymus:38.70 bone marrow:19.70 adipose:40.30 bone:76.80 skin:96
GeneChip cerebrum:7.66 cerebellum:7.40 brain stem:7.82 corpus callosum/glia:7.03 pineal gland:- peripheral nerve:7.87 spine:7.50 retina:- eye:- artery/aorta:6.77 vein:6.74 lymphnode:6.81 peripheral blood:- spleen:6.59 thymus:8.16 bone marrow:6.44 adipose:6.89 bone:- skin:7.09
CAGE cerebrum:4.62 cerebellum:- brain stem:4.49 corpus callosum/glia:3.74 pineal gland:4.78 peripheral nerve:- spine:4.53 retina:- eye:- artery/aorta:3.59 vein:3.35 lymphnode:3.44 peripheral blood:- spleen:3.76 thymus:3.95 bone marrow:- adipose:3.96 bone:- skin:-
RNA-seq cerebrum:5.94 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.35 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.18 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:91.10 placenta:47.40 prostate:101.40 ovary:74.50 testis:134.10 heart:102.20 muscle:321.40 esophagus:- stomach:42.50 intestine:32.40 colon:84.80     liver/hepato:116.10        lung:83.10    bladder:- kidney:124.80 pituitary:- thyroid/parathyroid:- adrenal gland:457.10 pancreas:71.10 breast:46.50 salivary:-
GeneChip uterus:7.53 placenta:7.42 prostate:7.74 ovary:7.02 testis:7.66 heart:6.73 muscle:7.18 esophagus:7.41 stomach:6.90 intestine:6.99 colon:5.93 liver/hepato:6.89 lung:6.44 bladder:- kidney:6.31 pituitary:7.41 thyroid/parathyroid:6.76 adrenal gland:7.32 pancreas:6.55 breast:6.81 salivary:6.23
CAGE uterus:3.96 placenta:4.06 prostate:4.05 ovary:3.83 testis:4.03 heart:3.56 muscle:4.12 esophagus:4.14 stomach:- intestine:3.92 colon:3.62     liver/hepato:4.15    lung:3.65 bladder:4.32 kidney:3.99 pituitary:4.79 thyroid/parathyroid:3.83 adrenal gland:- pancreas:3.37 breast:3.22 salivary:3.57
RNA-seq uterus:- placenta:- prostate:5.22 ovary:4.64 testis:5.10 heart:3.84 muscle:4.02 esophagus:- stomach:- intestine:- colon:5.23     liver/hepato:4.52        lung:4.36    bladder:- kidney:4.55 pituitary:- thyroid/parathyroid:4.82 adrenal gland:4.44 pancreas:- breast:4.71 salivary:-

Gene Information

IDs

Refseq ID NM_003350
Gene ID 7336
Unigene ID Hs.491695
Probe set ID 209096_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169139
GTEx ID ENSG00000169139

Orthologous Gene

Mouse[8]  NM_001159351, NM_023585
Rat[1]  NM_183052, NM_023585

Chromosomal Region

8q11.21  [48,920,960  -  48,976,511]

Gene Family (Interpro ID)

IPR000608  Ubiquitin-conjugating enzyme, E2
IPR016135  Ubiquitin-conjugating enzyme/RWD-like

Link to Pubmed  (Pubmed ID)

9199207
9418904
9705497
10089880
11473244
11473255
12039045
12477932
12569095
12665801
12834344
12847084
14517261
14562038
14695475
14702039
15147900
15489334
15725630
15749714
15952783
16112642
16122702
16129784
16169070
16215985
16518696
16786304
17108083
17218787
17349954
17964296
18178771
18284681
18316726
18678647
19549727
20029029
20047764
21114314
21139048
21143188
21774837
21890473
21906983
22505724
22589545
22679021
22939629
23000965
23751493
24076975
24816145
24846979

Gene Ontology  (GO ID)

Biological Process

GO:0008283  cell proliferation
GO:0000729  DNA double-strand break processing
GO:0043524  negative regulation of neuron apoptosis
GO:0045739  positive regulation of DNA repair
GO:0010976  positive regulation of neuron projection development
GO:0032436  positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051965  positive regulation of synaptogenesis
GO:0000209  protein polyubiquitination
GO:0016567  protein ubiquitination
GO:0006282  regulation of DNA repair

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0031372  UBC13-MMS2 complex

Molecular Function

GO:0016881  acid-amino acid ligase activity
GO:0005515  protein binding