nuclear receptor subfamily 1, group H, member 2

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Synonym

nuclear receptor subfamily 1, group H, member 2, NER, RIP15, Oxysterols receptor LXR-beta, NER-I, LXRB, Nuclear receptor NER, Nuclear orphan receptor LXR-beta, NR1H2, Liver X receptor beta, LXR-b, Ubiquitously-expressed nuclear receptor

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:157.60 cerebellum:201.50 brain stem:- corpus callosum/glia:262.50 pineal gland:- peripheral nerve:153.40 spine:- retina:- eye:182.20 artery/aorta:179.90 vein:- lymphnode:343.80 peripheral blood:419 spleen:264.70 thymus:180.40 bone marrow:295.20 adipose:242 bone:345.50 skin:105.60
GeneChip cerebrum:6.81 cerebellum:6.74 brain stem:6.84 corpus callosum/glia:6.93 pineal gland:- peripheral nerve:6.62 spine:6.63 retina:- eye:- artery/aorta:7.18 vein:7.10 lymphnode:6.90 peripheral blood:- spleen:7 thymus:6.49 bone marrow:6.69 adipose:6.97 bone:- skin:6.67
CAGE cerebrum:3.93 cerebellum:- brain stem:4.08 corpus callosum/glia:3.94 pineal gland:4.16 peripheral nerve:- spine:4.18 retina:- eye:- artery/aorta:4.22 vein:4.03 lymphnode:3.75 peripheral blood:- spleen:3.87 thymus:3.63 bone marrow:- adipose:3.83 bone:- skin:-
RNA-seq cerebrum:3.35 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.08 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.65 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:173.20 placenta:178.50 prostate:225.30 ovary:74.50 testis:108.20 heart:89.40 muscle:140.60 esophagus:- stomach:191.20 intestine:324 colon:76.30     liver/hepato:84.40        lung:127.10    bladder:376.80 kidney:114.40 pituitary:- thyroid/parathyroid:1310 adrenal gland:50.80 pancreas:53.30 breast:158 salivary:328.40
GeneChip uterus:6.68 placenta:6.48 prostate:6.70 ovary:6.66 testis:6.85 heart:6.99 muscle:7.16 esophagus:7.13 stomach:6.78 intestine:6.74 colon:7 liver/hepato:6.80 lung:7.23 bladder:- kidney:7.03 pituitary:6.40 thyroid/parathyroid:7.05 adrenal gland:7.12 pancreas:6.53 breast:6.95 salivary:6.80
CAGE uterus:3.94 placenta:4.09 prostate:4.05 ovary:3.93 testis:4.02 heart:4.16 muscle:4.38 esophagus:4.10 stomach:- intestine:4.08 colon:3.71     liver/hepato:4.03    lung:4.07 bladder:4.11 kidney:4.02 pituitary:3.55 thyroid/parathyroid:3.99 adrenal gland:- pancreas:3.89 breast:3.56 salivary:3.90
RNA-seq uterus:- placenta:- prostate:4.80 ovary:4.04 testis:4.41 heart:3.57 muscle:4.57 esophagus:- stomach:- intestine:- colon:4.37     liver/hepato:3.18        lung:4.93    bladder:- kidney:3.83 pituitary:- thyroid/parathyroid:4.86 adrenal gland:4.58 pancreas:- breast:3.92 salivary:-

IDs

Refseq ID NM_007121
Gene ID 7376
Unigene ID Hs.432976
Probe set ID 218215_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000131408
GTEx ID ENSG00000131408

Orthologous Gene

Mouse[1]  NM_009473
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

Gene Ontology  (GO ID)

Biological Process

GO:0044255  cellular lipid metabolic process
GO:0042632  cholesterol homeostasis
GO:0010467  gene expression
GO:0010887  negative regulation of cholesterol storage
GO:0060336  negative regulation of interferon-gamma-mediated signaling pathway
GO:0032369  negative regulation of lipid transport
GO:0010745  negative regulation of macrophage derived foam cell differentiation
GO:0048550  negative regulation of pinocytosis
GO:0045861  negative regulation of proteolysis
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0032270  positive regulation of cellular protein metabolic process
GO:0010875  positive regulation of cholesterol efflux
GO:0032376  positive regulation of cholesterol transport
GO:0045723  positive regulation of fatty acid biosynthetic process
GO:0090108  positive regulation of high-density lipoprotein particle assembly
GO:0010884  positive regulation of lipid storage
GO:0051006  positive regulation of lipoprotein lipase activity
GO:0090187  positive regulation of pancreatic juice secretion
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0010867  positive regulation of triglyceride biosynthetic process
GO:0048384  retinoic acid receptor signaling pathway
GO:0006367  transcription initiation from RNA polymerase II promoter

Cellular Component

GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0004879  ligand-dependent nuclear receptor activity
GO:0005515  protein binding
GO:0046965  retinoid X receptor binding
GO:0043565  sequence-specific DNA binding
GO:0003707  steroid hormone receptor activity
GO:0008270  zinc ion binding