wingless-type MMTV integration site family, member 5A

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Synonym

hWNT5A, Protein Wnt-5a precursor, WNT5A

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.69 cerebellum:3.66 brain stem:3.68 corpus callosum/glia:3.88 pineal gland:- peripheral nerve:3.87 spine:4.04 retina:- eye:- artery/aorta:3.97 vein:4.03 lymphnode:4.69 peripheral blood:- spleen:4.11 thymus:4.19 bone marrow:3.30 adipose:4.37 bone:- skin:4.33
CAGE cerebrum:1.34 cerebellum:- brain stem:1.26 corpus callosum/glia:1.08 pineal gland:1.00 peripheral nerve:- spine:1.94 retina:- eye:- artery/aorta:1.38 vein:1.29 lymphnode:1.92 peripheral blood:- spleen:1.24 thymus:1.10 bone marrow:- adipose:0.36 bone:- skin:-
RNA-seq cerebrum:0.19 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.62 placenta:6.12 prostate:5.13 ovary:5.92 testis:3.68 heart:4.33 muscle:4.32 esophagus:6.21 stomach:4.57 intestine:4.93 colon:4.36 liver/hepato:4.22 lung:4.20 bladder:- kidney:4.06 pituitary:3.97 thyroid/parathyroid:4.92 adrenal gland:3.79 pancreas:4.44 breast:5.30 salivary:6.36
CAGE uterus:2.47 placenta:3.27 prostate:1.78 ovary:1.81 testis:1.23 heart:1.07 muscle:0.17 esophagus:2.30 stomach:- intestine:1.24 colon:1.70     liver/hepato:0.55    lung:1.60 bladder:1.84 kidney:1.14 pituitary:0.62 thyroid/parathyroid:1.05 adrenal gland:- pancreas:1.42 breast:1.36 salivary:3.11
RNA-seq uterus:- placenta:- prostate:0.52 ovary:1.10 testis:0.66 heart:0.34 muscle:0.19 esophagus:- stomach:- intestine:- colon:0.32     liver/hepato:0.04        lung:0.49    bladder:- kidney:0.26 pituitary:- thyroid/parathyroid:0.49 adrenal gland:0.50 pancreas:- breast:0.25 salivary:-

IDs

Refseq ID NM_003392
Gene ID 7474
Unigene ID -
Probe set ID 213425_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000114251
GTEx ID ENSG00000114251

Orthologous Gene

Mouse[2]  NM_009524
Rat[1]  NM_022631

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

8167409
8288227
8537388
8889548
9054360
9787155
10491302
10557084
11956659
12086864
12165812
12244165
12477932
12482967
12805222
12839624
12841867
12952940
14702039
15040835
15067324
15389636
15588944
15592517
15735754
16169547
16258938
16344560
16569699
16601243
16880514
16914445
16996564
17035633
17227781
17426020
17458904
17463182
17486081
17525119
17546602
17709179
17848411
17937436
17952396
17956663
17967789
17976063
17986384
17992121
18032022
18172252
18174174
18174455
18287027
18413325
18420933
18456733
18462958
18477650
18541964
18615587
18632632
18656562
18703641
18794093
18990694
19048125
19061910
19063862
19074888
19099253
19148501
19171330
19177143
19244247
19251946
19277043
19399181
19453261
19467340
19473452
19492056
19520808
19561643
19582886
19651774
19696445
19760930
19802008
19847889
19849855
19874313
19878652
19910923
19918918
19940551
19946729
19956879
20008136
20032469
20083703
20101234
20376066
20379614
20429785
20454608
20518933
20525402
20554957
20603606
20628624
20634891
20639201
20890934
20955350
21069266
21115903
21165581
21205070
21209903
21270611
21285942
21342370
21344486
21352264
21365928
21431850
21461571
21587258
21672426
21816908
21871017
21918189
21963094
21980498
22039506
22101459
22124122
22128168
22162112
22293903
22384081
22384249
22485170
22493546
22547701
22609948
22655072
22694338
22781592
22825874
23001722
23046419
23054609
23075330
23159080
23178630
23254341
23265959
23266365
23271023
23278988
23342259
23349696
23353182
23359789
23396967
23417837
23462101
23469623
23484019
23539626
23615002
23653377
23660959
23679576
23716599
23764752
23947922
23963164
24091015
24156409
24250222
24293407
24335906
24346691
24518599
24706725

Gene Ontology  (GO ID)

Biological Process

GO:0007257  activation of JUN kinase activity
GO:0000187  activation of MAPK activity
GO:0032148  activation of protein kinase B activity
GO:0001667  ameboidal cell migration
GO:0007411  axon guidance
GO:0051216  cartilage development
GO:0045165  cell fate commitment
GO:0034613  cellular protein localization
GO:0071277  cellular response to calcium ion
GO:0071346  cellular response to interferon-gamma
GO:0071222  cellular response to lipopolysaccharide
GO:0071300  cellular response to retinoic acid
GO:0060067  cervix development
GO:0090103  cochlea morphogenesis
GO:0060029  convergent extension involved in organogenesis
GO:0008595  determination of anterior/posterior axis, embryo
GO:0042733  embryonic digit morphogenesis
GO:0048706  embryonic skeletal system development
GO:0060750  epithelial cell proliferation involved in mammary gland duct elongation
GO:0001837  epithelial to mesenchymal transition
GO:0001736  establishment of planar polarity
GO:0060324  face development
GO:0048806  genitalia development
GO:0001947  heart looping
GO:0071425  hemopoietic stem cell proliferation
GO:0007442  hindgut morphogenesis
GO:0048850  hypophysis morphogenesis
GO:0030216  keratinocyte differentiation
GO:0060599  lateral sprouting involved in mammary gland duct morphogenesis
GO:0002088  lens development in camera-type eye
GO:0030324  lung development
GO:0008584  male gonad development
GO:0060744  mammary gland branching involved in thelarche
GO:0060638  mesenchymal-epithelial cell signaling
GO:0007494  midgut development
GO:0050919  negative chemotaxis
GO:0043066  negative regulation of apoptosis
GO:0048843  negative regulation of axon extension involved in axon guidance
GO:0030514  negative regulation of BMP signaling pathway
GO:0050680  negative regulation of epithelial cell proliferation
GO:0045599  negative regulation of fat cell differentiation
GO:0040037  negative regulation of fibroblast growth factor receptor signaling pathway
GO:0060686  negative regulation of prostatic bud formation
GO:0051964  negative regulation of synaptogenesis
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0001843  neural tube closure
GO:0030182  neuron differentiation
GO:0021891  olfactory bulb interneuron development
GO:0003408  optic cup formation involved in camera-type eye development
GO:0060021  palate development
GO:0003323  pancreatic B cell development
GO:0090179  planar cell polarity pathway involved in neural tube closure
GO:0045766  positive regulation of angiogenesis
GO:0030825  positive regulation of cGMP metabolic process
GO:0045080  positive regulation of chemokine biosynthetic process
GO:0002741  positive regulation of cytokine secretion during immune response
GO:0010595  positive regulation of endothelial cell migration
GO:0001938  positive regulation of endothelial cell proliferation
GO:0048146  positive regulation of fibroblast proliferation
GO:0050729  positive regulation of inflammatory response
GO:0032729  positive regulation of interferon-gamma production
GO:0050718  positive regulation of interleukin-1 beta secretion
GO:0032755  positive regulation of interleukin-6 production
GO:0046330  positive regulation of JNK cascade
GO:0043032  positive regulation of macrophage activation
GO:0060907  positive regulation of macrophage cytokine production
GO:0045836  positive regulation of meiosis
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0010976  positive regulation of neuron projection development
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0045778  positive regulation of ossification
GO:0033138  positive regulation of peptidyl-serine phosphorylation
GO:0010800  positive regulation of peptidyl-threonine phosphorylation
GO:0045732  positive regulation of protein catabolic process
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0060760  positive regulation of response to cytokine stimulus
GO:0010820  positive regulation of T cell chemotaxis
GO:0070245  positive regulation of thymocyte apoptosis
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0060340  positive regulation of type I interferon-mediated signaling pathway
GO:0090009  primitive streak formation
GO:0006468  protein amino acid phosphorylation
GO:0060762  regulation of branching involved in mammary gland duct morphogenesis
GO:0010033  response to organic substance
GO:0001756  somitogenesis
GO:0060157  urinary bladder development
GO:0060065  uterus development
GO:0060068  vagina development
GO:0016055  Wnt receptor signaling pathway
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0007223  Wnt receptor signaling pathway, calcium modulating pathway
GO:0042060  wound healing

Cellular Component

GO:0009986  cell surface
GO:0005788  endoplasmic reticulum lumen
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005796  Golgi lumen
GO:0005886  plasma membrane
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005125  cytokine activity
GO:0044212  DNA regulatory region binding
GO:0005109  frizzled binding
GO:0005110  frizzled-2 binding
GO:0019904  protein domain specific binding
GO:0048018  receptor agonist activity
GO:0005115  receptor tyrosine kinase-like orphan receptor binding
GO:0003700  transcription factor activity