wingless-type MMTV integration site family, member 11

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Synonym

MGC141948, MGC141946, WNT11, Protein Wnt-11 precursor, HWNT11

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:-
GeneChip cerebrum:4.75 cerebellum:4.75 brain stem:4.86 corpus callosum/glia:4.70 pineal gland:- peripheral nerve:4.70 spine:4.55 retina:- eye:- artery/aorta:5.13 vein:5.67 lymphnode:4.84 peripheral blood:- spleen:4.68 thymus:4.43 bone marrow:4.57 adipose:6.05 bone:- skin:5.20
CAGE cerebrum:0.30 cerebellum:- brain stem:0.49 corpus callosum/glia:0.66 pineal gland:0 peripheral nerve:- spine:0.09 retina:- eye:- artery/aorta:2.08 vein:2.27 lymphnode:0.67 peripheral blood:- spleen:1.15 thymus:0.12 bone marrow:- adipose:2.76 bone:- skin:-
RNA-seq cerebrum:0.16 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.35 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.16 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:10.90 prostate:- ovary:- testis:- heart:63.90 muscle:- esophagus:- stomach:- intestine:- colon:33.90     liver/hepato:-        lung:68.40    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.55 placenta:4.67 prostate:4.66 ovary:4.52 testis:4.46 heart:5 muscle:5.42 esophagus:4.77 stomach:4.53 intestine:4.93 colon:4.81 liver/hepato:5.09 lung:4.96 bladder:- kidney:4.67 pituitary:4.68 thyroid/parathyroid:5.12 adrenal gland:5.70 pancreas:4.94 breast:4.95 salivary:4.66
CAGE uterus:1.07 placenta:1.59 prostate:1.46 ovary:1.41 testis:1.12 heart:1.37 muscle:1.45 esophagus:1.46 stomach:- intestine:1.81 colon:1.52     liver/hepato:1.44    lung:1.60 bladder:1.45 kidney:0.49 pituitary:0.95 thyroid/parathyroid:1.75 adrenal gland:- pancreas:1.59 breast:3.09 salivary:1.28
RNA-seq uterus:- placenta:- prostate:2.28 ovary:0.88 testis:1.33 heart:0.74 muscle:0.75 esophagus:- stomach:- intestine:- colon:2.05     liver/hepato:0.74        lung:2.11    bladder:- kidney:0.45 pituitary:- thyroid/parathyroid:1.70 adrenal gland:1.40 pancreas:- breast:2.57 salivary:-

Gene Information

IDs

Refseq ID NM_004626
Gene ID 7481
Unigene ID Hs.108219
Probe set ID 206737_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000085741
GTEx ID ENSG00000085741

Orthologous Gene

Mouse[1]  NM_009519
Rat [0]  

Chromosomal Region

11q13.5  [75,897,369  -  75,921,803]

Gene Family (Interpro ID)

IPR005817  Wnt superfamily

Link to Pubmed  (Pubmed ID)

8167409
9757009
11712081
12477932
15084607
15489334
15543138
15701629
15708567
16303743
17967789
18413325
18572162
19265664
19453261
19847889
20062060
20103596
20219091
20379614
20819778
20870744
20890934
21139048
21242973
21280163
21903761
22161723
23549873
24082114

Gene Ontology  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0048844  artery morphogenesis
GO:0030282  bone mineralization
GO:0045165  cell fate commitment
GO:0071300  cellular response to retinoic acid
GO:0060197  cloacal septation
GO:0048706  embryonic skeletal system development
GO:0060484  lung-associated mesenchyme development
GO:0043066  negative regulation of apoptosis
GO:0060548  negative regulation of cell death
GO:0030308  negative regulation of cell growth
GO:0030336  negative regulation of cell migration
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0090090  negative regulation of Wnt receptor signaling pathway through beta-catenin
GO:0030182  neuron differentiation
GO:0001649  osteoblast differentiation
GO:0003151  outflow tract morphogenesis
GO:0060021  palate development
GO:0043065  positive regulation of apoptosis
GO:0030335  positive regulation of cell migration
GO:0010628  positive regulation of gene expression
GO:0045860  positive regulation of protein kinase activity
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0032320  positive regulation of Ras GTPase activity
GO:0051496  positive regulation of stress fiber formation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0032915  positive regulation of transforming growth factor-beta2 production
GO:0006468  protein amino acid phosphorylation
GO:0034394  protein localization at cell surface
GO:0070830  tight junction assembly
GO:0060675  ureteric bud morphogenesis
GO:0060412  ventricular septum morphogenesis
GO:0060070  Wnt receptor signaling pathway through beta-catenin

Cellular Component

GO:0005737  cytoplasm
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0005109  frizzled binding
GO:0030295  protein kinase activator activity
GO:0005099  Ras GTPase activator activity