calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Synonym

HPCA, FHM, CACNA1A, MHP1, CAV2.1, CACN3, Voltage-gated calcium channel subunit alpha Cav2.1, CACH4, APCA, MHP, EA2, Brain calcium channel I, CACNL1A4, SCA6, BI

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:8.48

cerebellum:11.48

brain stem:8.04

corpus callosum/glia:7.18

pineal gland:-

peripheral nerve:7.36

spine:7.43

retina:-

eye:-

artery/aorta:5.43

vein:5.66

lymphnode:6.14

peripheral blood:-

spleen:5.92

thymus:5.22

bone marrow:5.14

adipose:5.53

bone:-

skin:5.35

CAGE

cerebrum:3.27

cerebellum:-

brain stem:2.00

corpus callosum/glia:1.82

pineal gland:2.43

peripheral nerve:-

spine:2.00

retina:-

eye:-

artery/aorta:0.79

vein:0.18

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:2.23

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.17

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.06

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:4.30

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:88.90

breast:-

salivary:-

GeneChip

uterus:5.76

placenta:5.17

prostate:4.85

ovary:5.63

testis:6.13

heart:5.76

muscle:5.11

esophagus:5.31

stomach:6.19

intestine:6.04

colon:5.82

liver/hepato:5.13

lung:4.69

bladder:-

kidney:5.34

pituitary:6.45

thyroid/parathyroid:5.01

adrenal gland:5.95

pancreas:6.11

breast:5.76

salivary:6.08

CAGE

uterus:0.43

placenta:0

prostate:0.15

ovary:0.20

testis:1.21

heart:0.22

muscle:0.09

esophagus:0.18

stomach:-

intestine:0.14

colon:0.12

liver/hepato:0

lung:0

bladder:0.26

kidney:0.08

pituitary:0.71

thyroid/parathyroid:0.06

adrenal gland:-

pancreas:0

breast:0.55

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.12

ovary:0.10

testis:0.00

heart:0.02

muscle:0.04

esophagus:-

stomach:-

intestine:-

colon:0.04

liver/hepato:0.02

lung:0.06

bladder:-

kidney:0.01

pituitary:-

thyroid/parathyroid:0.12

adrenal gland:0.35

pancreas:-

breast:0.30

salivary:-

IDs

Refseq ID	NM_001127221
Gene ID	773
Unigene ID	Hs.501632
Probe set ID	214933_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000141837
GTEx ID	ENSG00000141837

Orthologous Gene

Mouse[1]	NM_007578
Rat[1]	NM_012918

Chromosomal Region

19p13.2 [13,317,256 - 13,617,274]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_7 [5,001 - 305,019]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002077	Voltage-dependent calcium channel, alpha-1 subunit
IPR005448	Voltage-dependent calcium channel, P/Q-type, alpha-1 subunit

Gene Ontology (GO ID)

Biological Process

GO:0007628	adult walking behavior
GO:0048266	behavioral response to pain
GO:0017156	calcium ion-dependent exocytosis
GO:0048791	calcium ion-dependent exocytosis of neurotransmitter
GO:0008219	cell death
GO:0016049	cell growth
GO:0030644	cellular chloride ion homeostasis
GO:0021679	cerebellar molecular layer development
GO:0021702	cerebellar Purkinje cell differentiation
GO:0021590	cerebellum maturation
GO:0048813	dendrite morphogenesis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0006112	energy reserve metabolic process
GO:0014051	gamma-aminobutyric acid secretion
GO:0007214	gamma-aminobutyric acid signaling pathway
GO:0006006	glucose metabolic process
GO:0042445	hormone metabolic process
GO:0051899	membrane depolarization
GO:0050883	musculoskeletal movement, spinal reflex action
GO:0032353	negative regulation of hormone biosynthetic process
GO:0043524	negative regulation of neuron apoptosis
GO:0050885	neuromuscular process controlling balance
GO:0007274	neuromuscular synaptic transmission
GO:0042133	neurotransmitter metabolic process
GO:0043113	receptor clustering
GO:0014056	regulation of acetylcholine secretion
GO:0050770	regulation of axonogenesis
GO:0017158	regulation of calcium ion-dependent exocytosis
GO:0050796	regulation of insulin secretion
GO:0060024	rhythmic synaptic transmission
GO:0021522	spinal cord motor neuron differentiation
GO:0000096	sulfur amino acid metabolic process
GO:0007416	synapse assembly
GO:0007268	synaptic transmission
GO:0035249	synaptic transmission, glutamatergic
GO:0021750	vestibular nucleus development

Cellular Component

GO:0042995	cell projection
GO:0043025	cell soma
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0005891	voltage-gated calcium channel complex

Molecular Function

GO:0008331	high voltage-gated calcium channel activity
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0019905	syntaxin binding
GO:0005245	voltage-gated calcium channel activity

calcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function