paired box 8

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Synonym

paired box gene 8, PAX8, Paired box protein Pax-8

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:105.50

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:129.30

artery/aorta:-

vein:-

lymphnode:111.20

peripheral blood:36.40

spleen:-

thymus:12.90

bone marrow:-

adipose:40.30

bone:64

skin:384

GeneChip

cerebrum:7.55

cerebellum:7.55

brain stem:7.57

corpus callosum/glia:7.57

pineal gland:-

peripheral nerve:7.65

spine:7.81

retina:-

eye:-

artery/aorta:7.48

vein:7.53

lymphnode:7.54

peripheral blood:-

spleen:7.42

thymus:7.34

bone marrow:7.72

adipose:7.64

bone:-

skin:7.51

CAGE

cerebrum:0.98

cerebellum:-

brain stem:1.04

corpus callosum/glia:0.96

pineal gland:1.49

peripheral nerve:-

spine:1.72

retina:-

eye:-

artery/aorta:1.68

vein:1.69

lymphnode:1.42

peripheral blood:-

spleen:0.76

thymus:1.20

bone marrow:-

adipose:2.07

bone:-

skin:-

RNA-seq

cerebrum:0.01

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.02

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.03

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:109.40

placenta:83.80

prostate:33.80

ovary:260.80

testis:43.30

heart:25.50

muscle:-

esophagus:-

stomach:-

intestine:-

colon:76.30

liver/hepato:-

lung:97.80

bladder:-

kidney:291.10

pituitary:-

thyroid/parathyroid:1801.20

adrenal gland:50.80

pancreas:62.20

breast:18.60

salivary:-

GeneChip

uterus:7.85

placenta:7.56

prostate:7.27

ovary:8.13

testis:7.61

heart:7.49

muscle:7.45

esophagus:7.67

stomach:7.52

intestine:7.74

colon:7.69

liver/hepato:7.50

lung:7.42

bladder:-

kidney:9.97

pituitary:7.94

thyroid/parathyroid:11.54

adrenal gland:7.70

pancreas:8.19

breast:7.43

salivary:7.68

CAGE

uterus:2.18

placenta:1.69

prostate:1.89

ovary:2.83

testis:2.21

heart:1.15

muscle:0.27

esophagus:1.96

stomach:-

intestine:1.77

colon:0.66

liver/hepato:0.71

lung:1.51

bladder:1.78

kidney:5.55

pituitary:1.33

thyroid/parathyroid:6.07

adrenal gland:-

pancreas:1.21

breast:2.02

salivary:1.95

RNA-seq

uterus:-

placenta:-

prostate:1.18

ovary:0.10

testis:0.70

heart:0.18

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.07

liver/hepato:0.23

lung:0.26

bladder:-

kidney:4.68

pituitary:-

thyroid/parathyroid:0.23

adrenal gland:0.11

pancreas:-

breast:0.12

salivary:-

IDs

Refseq ID	NM_013992
Gene ID	7849
Unigene ID	Hs.469728
Probe set ID	121_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000125618
GTEx ID	ENSG00000125618

Orthologous Gene

Mouse[1]	NM_011040
Rat [0]

Chromosomal Region

2q13 [113,973,574 - 114,036,527]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR001523	Paired box protein, N-terminal
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0009653	anatomical structure morphogenesis
GO:0001658	branching involved in ureteric bud morphogenesis
GO:0071371	cellular response to gonadotropin stimulus
GO:0007417	central nervous system development
GO:0042472	inner ear morphogenesis
GO:0001822	kidney development
GO:0003337	mesenchymal to epithelial transition involved in metanephros morphogenesis
GO:0001823	mesonephros development
GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0048793	pronephros development
GO:0042981	regulation of apoptosis
GO:0030878	thyroid gland development
GO:0006351	transcription, DNA-dependent
GO:0001655	urogenital system development

Cellular Component

GO:0005730	nucleolus
GO:0005654	nucleoplasm
GO:0005634	nucleus

Molecular Function

GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0005515	protein binding
GO:0004996	thyroid-stimulating hormone receptor activity
GO:0003700	transcription factor activity

paired box 8

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function