phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Synonym

LDL-associated phospholipase A2, PLA2G7, 2-acetyl-1-alkylglycerophosphocholine esterase, PAF acetylhydrolase, LDL-PLA(2), PAFAH, 1-alkyl-2-acetylglycerophosphocholine esterase, PAF 2-acylhydrolase, LDL-PLA2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:72.90

spleen:37.80

thymus:-

bone marrow:-

adipose:-

bone:12.80

skin:24

GeneChip

cerebrum:3.23

cerebellum:3.20

brain stem:3.44

corpus callosum/glia:3.19

pineal gland:-

peripheral nerve:3.14

spine:3.39

retina:-

eye:-

artery/aorta:3.01

vein:3.05

lymphnode:5.02

peripheral blood:-

spleen:4.95

thymus:3.71

bone marrow:4.07

adipose:3.70

bone:-

skin:3.60

CAGE

cerebrum:1.44

cerebellum:-

brain stem:1.62

corpus callosum/glia:1.49

pineal gland:0.14

peripheral nerve:-

spine:1.76

retina:-

eye:-

artery/aorta:1.48

vein:3.17

lymphnode:2.80

peripheral blood:-

spleen:4.02

thymus:2.32

bone marrow:-

adipose:4.59

bone:-

skin:-

RNA-seq

cerebrum:0.41

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.14

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.56

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:29.10

prostate:22.50

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:-

liver/hepato:21.10

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:44.50

breast:9.30

salivary:-

GeneChip

uterus:3.68

placenta:4.48

prostate:5.50

ovary:3.16

testis:2.83

heart:2.97

muscle:3.22

esophagus:2.81

stomach:3.37

intestine:3.35

colon:3.08

liver/hepato:3.96

lung:4.94

bladder:-

kidney:2.89

pituitary:3.31

thyroid/parathyroid:5.51

adrenal gland:3.27

pancreas:3.09

breast:3.67

salivary:3.21

CAGE

uterus:0.91

placenta:3.23

prostate:2.13

ovary:2.13

testis:0.75

heart:0.78

muscle:0.72

esophagus:0.77

stomach:-

intestine:1.48

colon:1.33

liver/hepato:1.63

lung:3.60

bladder:1.86

kidney:0.39

pituitary:1.57

thyroid/parathyroid:2.86

adrenal gland:-

pancreas:0

breast:0.90

salivary:1.15

RNA-seq

uterus:-

placenta:-

prostate:1.44

ovary:0.99

testis:0.18

heart:0.18

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.11

liver/hepato:0.23

lung:1.26

bladder:-

kidney:0.07

pituitary:-

thyroid/parathyroid:2.50

adrenal gland:0.83

pancreas:-

breast:0.79

salivary:-

IDs

Refseq ID	NM_005084
Gene ID	7941
Unigene ID	Hs.584823
Probe set ID	206214_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000146070
GTEx ID	ENSG00000146070

Orthologous Gene

Mouse[1]	NM_013737
Rat[1]	NM_001009353

Chromosomal Region

6p12.3 [46,671,938 - 46,703,430]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR016715	PAF acetylhydrolase
IPR005065	Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II

GO:0044267	cellular protein metabolic process
GO:0016042	lipid catabolic process
GO:0034440	lipid oxidation
GO:0034374	low-density lipoprotein particle remodeling
GO:0034441	plasma lipoprotein oxidation
GO:0050729	positive regulation of inflammatory response
GO:0090026	positive regulation of monocyte chemotaxis

GO:0005576	extracellular region
GO:0034362	low-density lipoprotein particle

GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity
GO:0047499	calcium-independent phospholipase A2 activity
GO:0005543	phospholipid binding

phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function