homeobox containing 1

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Synonym

homeobox containing 1, FLJ21616, Homeobox-containing protein 1, HMBOX1, HNF1LA, PBHNF

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:35.30 artery/aorta:30 vein:- lymphnode:40.40 peripheral blood:18.20 spleen:- thymus:- bone marrow:59 adipose:- bone:- skin:100.80
GeneChip cerebrum:8.19 cerebellum:7.71 brain stem:8.42 corpus callosum/glia:8.64 pineal gland:- peripheral nerve:8.95 spine:8.81 retina:- eye:- artery/aorta:8.02 vein:7.69 lymphnode:8.39 peripheral blood:- spleen:8.74 thymus:8.98 bone marrow:7.91 adipose:8.06 bone:- skin:7.66
CAGE cerebrum:3.87 cerebellum:- brain stem:4.12 corpus callosum/glia:3.97 pineal gland:3.98 peripheral nerve:- spine:4.39 retina:- eye:- artery/aorta:3.53 vein:3.72 lymphnode:3.29 peripheral blood:- spleen:3.59 thymus:3.72 bone marrow:- adipose:3.76 bone:- skin:-
RNA-seq cerebrum:2.04 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.87 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.86 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:25.50 prostate:33.80 ovary:745.30 testis:38.90 heart:- muscle:- esophagus:- stomach:42.50 intestine:- colon:42.40     liver/hepato:10.60        lung:14.70    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:152.40 pancreas:53.30 breast:37.20 salivary:-
GeneChip uterus:8.31 placenta:7.89 prostate:7.64 ovary:8.29 testis:8.20 heart:7.98 muscle:7.54 esophagus:7.62 stomach:8.22 intestine:7.54 colon:8.12 liver/hepato:8.15 lung:8.63 bladder:- kidney:8.16 pituitary:8.23 thyroid/parathyroid:8.35 adrenal gland:9.05 pancreas:7.44 breast:8.25 salivary:7.81
CAGE uterus:3.88 placenta:3.53 prostate:3.33 ovary:3.47 testis:3.55 heart:3.48 muscle:3.04 esophagus:3.11 stomach:- intestine:3.28 colon:3.02     liver/hepato:3.13    lung:3.76 bladder:3.51 kidney:3.27 pituitary:3.92 thyroid/parathyroid:3.39 adrenal gland:- pancreas:2.76 breast:3.58 salivary:3.56
RNA-seq uterus:- placenta:- prostate:0.91 ovary:1.38 testis:1.91 heart:1.73 muscle:0.41 esophagus:- stomach:- intestine:- colon:0.82     liver/hepato:0.86        lung:1.61    bladder:- kidney:1.26 pituitary:- thyroid/parathyroid:1.41 adrenal gland:1.03 pancreas:- breast:1.31 salivary:-

Gene Information

IDs

Refseq ID NM_001135726
Gene ID 79618
Unigene ID Hs.591836
Probe set ID 219269_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000147421
GTEx ID ENSG00000147421

Orthologous Gene

Mouse[1]  NM_177338
Rat[1]  NM_177338

Chromosomal Region

8p21.1  [28,747,911  -  28,922,281]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

12477932
14702039
15489334
16751776
16825764
18983639
19471022
19728927
19757162
20182437
20379614
21693764
21706044
21832049
21839858
21988832
22320217
22990118
23251661
23685356
23813958

Gene Ontology  (GO ID)

Biological Process

GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity