RUN and FYVE domain containing 1

 jump to detail

Synonym

RUN and FYVE domain containing 1, Rab4-interacting protein, FYVE-finger protein EIP1, ZFYVE12, FLJ22251, RUFY1, RUN and FYVE domain-containing protein 1, Zinc finger FYVE domain-containing protein 12, La-binding protein 1, RABIP4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.50 cerebellum:63 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:118.60 eye:41.10 artery/aorta:- vein:- lymphnode:141.50 peripheral blood:72.90 spleen:94.50 thymus:25.80 bone marrow:59 adipose:- bone:25.60 skin:57.60
GeneChip cerebrum:7.45 cerebellum:7.19 brain stem:7.43 corpus callosum/glia:7.65 pineal gland:- peripheral nerve:7.53 spine:7.66 retina:- eye:- artery/aorta:7.90 vein:7.74 lymphnode:8.21 peripheral blood:- spleen:8.44 thymus:8.42 bone marrow:8.52 adipose:7.93 bone:- skin:8.50
CAGE cerebrum:3.19 cerebellum:- brain stem:3.10 corpus callosum/glia:3.20 pineal gland:2.93 peripheral nerve:- spine:3.19 retina:- eye:- artery/aorta:3.27 vein:3.51 lymphnode:3.27 peripheral blood:- spleen:3.56 thymus:3.17 bone marrow:- adipose:3.35 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.54 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:21.90 prostate:33.80 ovary:- testis:4.30 heart:25.50 muscle:100.50 esophagus:- stomach:42.50 intestine:32.40 colon:42.40     liver/hepato:-        lung:122.20    bladder:- kidney:52 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:80 breast:46.50 salivary:-
GeneChip uterus:8.30 placenta:7.96 prostate:8.35 ovary:8.53 testis:7.40 heart:7.51 muscle:7.66 esophagus:8.39 stomach:7.88 intestine:7.92 colon:7.66 liver/hepato:7.61 lung:7.99 bladder:- kidney:8.06 pituitary:8.18 thyroid/parathyroid:8.36 adrenal gland:8.15 pancreas:7.36 breast:8.32 salivary:7.81
CAGE uterus:3.24 placenta:3.10 prostate:3.44 ovary:3.29 testis:2.96 heart:3.09 muscle:3.18 esophagus:3.39 stomach:- intestine:3.07 colon:3.38     liver/hepato:3.01    lung:3.50 bladder:3.11 kidney:3.46 pituitary:3.54 thyroid/parathyroid:3.55 adrenal gland:- pancreas:3.06 breast:3.95 salivary:2.95
RNA-seq uterus:- placenta:- prostate:1.03 ovary:1.15 testis:0.70 heart:0.10 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.05     liver/hepato:0.12        lung:0.00    bladder:- kidney:0.55 pituitary:- thyroid/parathyroid:0.37 adrenal gland:0.25 pancreas:- breast:0.47 salivary:-

Gene Information

IDs

Refseq ID NM_001040451
Gene ID 80230
Unigene ID Hs.306769
Probe set ID 218243_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000176783
GTEx ID ENSG00000176783

Orthologous Gene

Mouse[1]  NM_172557
Rat[1]  NM_001100727

Chromosomal Region

5q35.3  [178,977,559  -  179,037,027]

Gene Family (Interpro ID)

IPR000306  Zinc finger, FYVE-type
IPR011011  Zinc finger, FYVE/PHD-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

9050988
11172003
11877430
12477932
14617813
14702039
15342556
15489334
16344560
17233583
17868192
20534812
21139048
21906983
21988832
22558309
22797925
22863883
22911880
22939629
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0030100  regulation of endocytosis

Cellular Component

GO:0031901  early endosome membrane

Molecular Function

GO:0008289  lipid binding
GO:0005515  protein binding
GO:0008565  protein transporter activity
GO:0008270  zinc ion binding