hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

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Synonym

C(27)-3BETA-HSD, C(27) 3beta-HSD, PFIC4, HSD3B7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:1.24 cerebellum:- brain stem:1.61 corpus callosum/glia:1.86 pineal gland:1.31 peripheral nerve:- spine:1.97 retina:- eye:- artery/aorta:2.17 vein:2.09 lymphnode:1.91 peripheral blood:- spleen:2.34 thymus:0.54 bone marrow:- adipose:3.33 bone:- skin:-
RNA-seq cerebrum:0.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.62 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.93 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:1.98 placenta:1.96 prostate:2.08 ovary:2.49 testis:1.76 heart:2.01 muscle:1.59 esophagus:2.48 stomach:- intestine:2.79 colon:2.43     liver/hepato:4.31    lung:2.16 bladder:2.32 kidney:3.39 pituitary:1.32 thyroid/parathyroid:1.32 adrenal gland:- pancreas:2.98 breast:1.68 salivary:1.89
RNA-seq uterus:- placenta:- prostate:2.37 ovary:3.07 testis:1.55 heart:1.06 muscle:0.72 esophagus:- stomach:- intestine:- colon:1.84     liver/hepato:4.24        lung:1.19    bladder:- kidney:3.33 pituitary:- thyroid/parathyroid:1.54 adrenal gland:3.05 pancreas:- breast:3.46 salivary:-

Gene Information

IDs

Refseq ID NM_025193
Gene ID 80270
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000099377
GTEx ID ENSG00000099377

Orthologous Gene

Mouse[2]  NM_001040684, NM_133943
Rat[2]  NM_001040684, NM_133943

Chromosomal Region

16p11.2  [30,996,519  -  31,000,473]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11067870
12477932
12679481
14702039
15489334
16341674
16344560
19027726
20531254
21044367
21906983
21988832
22095780
23088713

Gene Ontology  (GO ID)

Biological Process

GO:0006699  bile acid biosynthetic process
GO:0008206  bile acid metabolic process

Cellular Component

GO:0005575  cellular_component
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane

Molecular Function

GO:0003854  3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0047016  cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity