WD repeat domain 61

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Synonym

WDR61, WD repeat protein 61, WD repeat domain 61, REC14, Meiotic recombination REC14 protein homolog

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:43.90 cerebellum:25.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:60 vein:133.30 lymphnode:20.20 peripheral blood:18.20 spleen:75.60 thymus:25.80 bone marrow:19.70 adipose:80.70 bone:- skin:38.40
GeneChip cerebrum:7.58 cerebellum:7.61 brain stem:7.82 corpus callosum/glia:7.67 pineal gland:- peripheral nerve:8.19 spine:8.04 retina:- eye:- artery/aorta:7.61 vein:7.76 lymphnode:7.66 peripheral blood:- spleen:7.56 thymus:8.21 bone marrow:7.68 adipose:7.96 bone:- skin:8.17
CAGE cerebrum:3.45 cerebellum:- brain stem:3.54 corpus callosum/glia:3.58 pineal gland:3.16 peripheral nerve:- spine:3.31 retina:- eye:- artery/aorta:3.42 vein:3.24 lymphnode:3.20 peripheral blood:- spleen:3.11 thymus:3.36 bone marrow:- adipose:3.35 bone:- skin:-
RNA-seq cerebrum:4.38 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.74 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.91 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:43.70 prostate:33.80 ovary:37.30 testis:73.50 heart:38.30 muscle:- esophagus:- stomach:- intestine:- colon:59.40     liver/hepato:10.60        lung:19.60    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip uterus:8.21 placenta:7.91 prostate:8.77 ovary:8.19 testis:8.85 heart:7.37 muscle:7.82 esophagus:8.13 stomach:7.55 intestine:7.88 colon:7.82 liver/hepato:7.32 lung:7.58 bladder:- kidney:8.15 pituitary:8.57 thyroid/parathyroid:8.46 adrenal gland:8.09 pancreas:8.01 breast:8.31 salivary:8.16
CAGE uterus:3.47 placenta:3.52 prostate:3.34 ovary:3.23 testis:3.85 heart:3.37 muscle:3.34 esophagus:3.42 stomach:- intestine:3.16 colon:3.30     liver/hepato:3.45    lung:3.28 bladder:3.15 kidney:3.66 pituitary:3.80 thyroid/parathyroid:3.50 adrenal gland:- pancreas:3.52 breast:2.69 salivary:3.72
RNA-seq uterus:- placenta:- prostate:4.82 ovary:4.79 testis:5.10 heart:3.66 muscle:3.52 esophagus:- stomach:- intestine:- colon:3.61     liver/hepato:4.26        lung:4.37    bladder:- kidney:5.07 pituitary:- thyroid/parathyroid:5.29 adrenal gland:4.59 pancreas:- breast:4.93 salivary:-

Gene Information

IDs

Refseq ID NM_025234
Gene ID 80349
Unigene ID Hs.513055
Probe set ID 221532_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000140395
GTEx ID ENSG00000140395

Orthologous Gene

Mouse[6]  NM_001025375, NM_001025376, NM_023191
Rat [0]  

Chromosomal Region

15q25.1  [78,575,577  -  78,592,136]

Gene Family (Interpro ID)

IPR020472  G-protein beta WD-40 repeat, region
IPR001680  WD40 repeat
IPR019782  WD40 repeat 2
IPR019781  WD40 repeat, subgroup
IPR011046  WD40 repeat-like-containing domain
IPR017986  WD40-repeat-containing domain
IPR015943  WD40/YVTN repeat-like-containing domain

Link to Pubmed  (Pubmed ID)

12477932
14702039
15161933
15489334
15761153
16024656
16169070
17041588
17148452
17203973
17207965
18029348
20178742
20305087
20360068
20541477
21070969
21139048
21145461
21726809
21906983
21963094
22190034
22451921
22863883
22939629
22990118
23524849
24337577

Gene Ontology  (GO ID)

Biological Process

GO:0045638  negative regulation of myeloid cell differentiation
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0032968  positive regulation of RNA elongation from RNA polymerase II promoter
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0006351  transcription, DNA-dependent
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0005737  cytoplasm
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0055087  Ski complex

Molecular Function

GO:0005515  protein binding