Nedd4 family interacting protein 1

 jump to detail

Synonym

PSEC0223, N4WBP5, Nedd4 family interacting protein 1, MGC10924, Putative NF-kappa-B-activating protein 164, NEDD4 WW domain-binding protein 5, NEDD4 family-interacting protein 1, Putative MAPK-activating protein PM13, PSEC0192, Putative NFKB and MAPK-activating protein, Breast cancer-associated protein SGA-1M, NDFIP1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:9.45 cerebellum:9.39 brain stem:9.50 corpus callosum/glia:8.55 pineal gland:- peripheral nerve:9.96 spine:9.21 retina:- eye:- artery/aorta:8.29 vein:8.21 lymphnode:7.81 peripheral blood:- spleen:8.38 thymus:8.34 bone marrow:7.32 adipose:8.50 bone:- skin:7.69
CAGE cerebrum:5.70 cerebellum:- brain stem:5.38 corpus callosum/glia:5.08 pineal gland:5.85 peripheral nerve:- spine:5.26 retina:- eye:- artery/aorta:5.24 vein:4.43 lymphnode:4.70 peripheral blood:- spleen:4.64 thymus:4.33 bone marrow:- adipose:4.60 bone:- skin:-
RNA-seq cerebrum:7.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.95 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.11 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:8.37 placenta:8.39 prostate:9.27 ovary:8.77 testis:8.66 heart:8.20 muscle:7.29 esophagus:7.68 stomach:8.09 intestine:8.28 colon:7.91 liver/hepato:8.58 lung:8.30 bladder:- kidney:9.02 pituitary:9.50 thyroid/parathyroid:9.52 adrenal gland:8.76 pancreas:8.21 breast:8.36 salivary:9.76
CAGE uterus:4.46 placenta:4.73 prostate:4.71 ovary:4.65 testis:4.85 heart:4.70 muscle:4.10 esophagus:4.36 stomach:- intestine:4.75 colon:4.50     liver/hepato:5.29    lung:4.77 bladder:4.54 kidney:4.96 pituitary:5.30 thyroid/parathyroid:5.34 adrenal gland:- pancreas:5.02 breast:4.88 salivary:5.60
RNA-seq uterus:- placenta:- prostate:5.81 ovary:5.55 testis:5.59 heart:4.77 muscle:4.27 esophagus:- stomach:- intestine:- colon:5.11     liver/hepato:5.53        lung:5.48    bladder:- kidney:6.02 pituitary:- thyroid/parathyroid:6.81 adrenal gland:4.60 pancreas:- breast:5.54 salivary:-

Gene Information

IDs

Refseq ID NM_030571
Gene ID 80762
Unigene ID -
Probe set ID 217800_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000131507
GTEx ID ENSG00000131507

Orthologous Gene

Mouse[1]  NM_022996
Rat[1]  NM_001013059

Chromosomal Region

5q31.3  [141,488,070  -  141,534,008]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11042109
11748237
12477932
12761501
14702039
15489334
16303743
16344560
17207965
18776082
18819914
18854154
19343052
19706893
20534535
20972266
21102463
21139048
21187286
21833088
21890473
21906983
21963094
22213801
22561531
23087404
23128233
24798731

Gene Ontology  (GO ID)

Biological Process

GO:0006879  cellular iron ion homeostasis
GO:0010629  negative regulation of gene expression
GO:0050728  negative regulation of inflammatory response
GO:0032713  negative regulation of interleukin-4 production
GO:0048294  negative regulation of isotype switching to IgE isotypes
GO:0051224  negative regulation of protein transport
GO:0042130  negative regulation of T cell proliferation
GO:0002829  negative regulation of T-helper 2 type immune response
GO:0032410  negative regulation of transporter activity
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0045732  positive regulation of protein catabolic process
GO:0031398  positive regulation of protein ubiquitination
GO:0048302  regulation of isotype switching to IgG isotypes
GO:0045619  regulation of lymphocyte differentiation
GO:0002761  regulation of myeloid leukocyte differentiation
GO:0007165  signal transduction
GO:0043162  ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway

Cellular Component

GO:0005938  cell cortex
GO:0010008  endosome membrane
GO:0005576  extracellular region
GO:0000139  Golgi membrane
GO:0016021  integral to membrane
GO:0048471  perinuclear region of cytoplasm

Molecular Function

GO:0005515  protein binding
GO:0004871  signal transducer activity
GO:0050699  WW domain binding