high mobility group AT-hook 2

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Synonym

High mobility group protein HMGI-C, HMGI-C, HMGA2, High mobility group AT-hook protein 2, HMGIC, LIPO, high mobility group AT-hook 2, BABL

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:92 spine:- retina:- eye:11.80 artery/aorta:30 vein:66.60 lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:177.60
GeneChip nodata
CAGE cerebrum:0.13 cerebellum:- brain stem:0.17 corpus callosum/glia:0.29 pineal gland:0.36 peripheral nerve:- spine:0.74 retina:- eye:- artery/aorta:1.03 vein:0 lymphnode:0.06 peripheral blood:- spleen:0.45 thymus:0.46 bone marrow:- adipose:1.71 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:18.20 prostate:11.30 ovary:111.80 testis:13 heart:12.80 muscle:- esophagus:- stomach:- intestine:- colon:42.40     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:27.90 salivary:-
GeneChip nodata
CAGE uterus:1.03 placenta:0.24 prostate:0.15 ovary:0.92 testis:2.49 heart:0.21 muscle:0.21 esophagus:0.26 stomach:- intestine:1.43 colon:2.32     liver/hepato:0    lung:0.50 bladder:0.46 kidney:0.39 pituitary:1.09 thyroid/parathyroid:0.53 adrenal gland:- pancreas:0 breast:0.90 salivary:0
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.27 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0 pancreas:- breast:0.03 salivary:-

IDs

Refseq ID NM_003484
Gene ID 8091
Unigene ID Hs.505924
Probe set ID -
Ensembl ID ENSG00000149948
GTEx ID ENSG00000149948

Orthologous Gene

Mouse[3]  NM_010441
Rat [0]  

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed  (Pubmed ID)

1762909
7501444
7529547
7606786
7670494
8198613
8824803
9003504
9772904
9892177
10398424
10586108
10636877
10889043
11034995
11066083
11390395
11406267
11839563
11894114
11921278
12419585
12477932
12505264
12569368
12649198
12693954
12778070
12781451
12799440
12874787
13679031
14603445
14614053
14627817
14645522
14647145
15026339
15146197
15225648
15618962
15618963
15755872
15882911
16061642
16077985
16222997
16271958
16276091
16293633
16322327
16341674
16375854
16766265
16831886
16901784
17005673
17045619
17078040
17222355
17322030
17324944
17332316
17426251
17437991
17477356
17624332
17654722
17767157
17854665
17917958
17917968
17935122
17943974
17957144
18193045
18202751
18214854
18375116
18391950
18391951
18391952
18403645
18413822
18425117
18452175
18505920
18784955
18828159
18832382
18843278
18850631
18980243
18983959
19003801
19132395
19136928
19139030
19179606
19215040
19223528
19262251
19266077
19298872
19317492
19343178
19376282
19431195
19454010
19454362
19465398
19508721
19521953
19549901
19551524
19584346
19602040
19609535
19837271
19898227
19913121
19930247
20004941
20007691
20058197
20195514
20228781
20347930
20368557
20397748
20461755
20544840
20551826
20581827
20597139
20610542
20628086
20804914
20804922
20834238
20881960
20889853
20926602
20946527
21150874
21224353
21252160
21267005
21412931
21498692
21533145
21536653
21598109
21692035
21769890
21803798
21906983
21907836
21921580
21931568
21998595
22017592
22019704
22021425
22137485
22139073
22199144
22221703
22246783
22250726
22404713
22461106
22476403
22504417
22504419
22547345
22564666
22593436
22613496
22726539
22843696
22885925
22974476
23111731
23134218
23134771
23135750
23144634
23202124
23237864
23240041
23268403
23276696
23307470
23525579
23529275
23530587
23536553
23563607
23591597
23593123
23625920
23633021
23639551
23704328
23716660
23722545
23738717
23765903
23898062
23969248
24122990
24144296
24145240
24305048
24468654
24571540

Gene Ontology  (GO ID)

Biological Process

GO:0030325  adrenal gland development
GO:0006284  base-excision repair
GO:0051301  cell division
GO:0021846  cell proliferation in forebrain
GO:0002062  chondrocyte differentiation
GO:0006325  chromatin organization
GO:0031052  chromosome breakage
GO:0030261  chromosome condensation
GO:0042769  DNA damage response, detection of DNA damage
GO:0001837  epithelial to mesenchymal transition
GO:0045444  fat cell differentiation
GO:0060613  fat pad development
GO:0031507  heterochromatin formation
GO:0008584  male gonad development
GO:0048762  mesenchymal cell differentiation
GO:0048333  mesodermal cell differentiation
GO:0003131  mesodermal-endodermal cell signaling
GO:0007067  mitosis
GO:0007095  mitotic cell cycle G2/M transition DNA damage checkpoint
GO:0007275  multicellular organismal development
GO:0043922  negative regulation by host of viral transcription
GO:0043066  negative regulation of apoptosis
GO:0048712  negative regulation of astrocyte differentiation
GO:0043392  negative regulation of DNA binding
GO:0045869  negative regulation of retroviral genome replication
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0021983  pituitary gland development
GO:0043065  positive regulation of apoptosis
GO:0071158  positive regulation of cell cycle arrest
GO:0010628  positive regulation of gene expression
GO:0040018  positive regulation of multicellular organism growth
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0010564  regulation of cell cycle process
GO:0060123  regulation of growth hormone secretion
GO:0006355  regulation of transcription, DNA-dependent
GO:0009615  response to virus
GO:0035019  somatic stem cell maintenance
GO:0007283  spermatogenesis
GO:0048863  stem cell differentiation

Cellular Component

GO:0000228  nuclear chromosome
GO:0005634  nucleus
GO:0032993  protein-DNA complex
GO:0071141  SMAD protein complex

Molecular Function

GO:0051575  5'-deoxyribose-5-phosphate lyase activity
GO:0003680  AT DNA binding
GO:0070742  C2H2 zinc finger domain binding
GO:0008301  DNA bending activity
GO:0003677  DNA binding
GO:0003906  DNA-(apurinic or apyrimidinic site) lyase activity
GO:0004677  DNA-dependent protein kinase activity
GO:0031492  nucleosomal DNA binding
GO:0005515  protein binding
GO:0046332  SMAD binding
GO:0008134  transcription factor binding