calcium/calmodulin-dependent protein kinase II alpha

Synonym

CaMKII a, CaMKIIa, CaMK II a, CaM-kinase II alpha chain, CAMK2A, KIAA0968, CAMKA, CaMK-II subunit alpha, CaMK IIa, CaM kinase II alpha subunit

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:8.18

cerebellum:6.34

brain stem:6.62

corpus callosum/glia:6.93

pineal gland:-

peripheral nerve:6.75

spine:6.69

retina:-

eye:-

artery/aorta:6.03

vein:6.24

lymphnode:5.97

peripheral blood:-

spleen:5.88

thymus:5.45

bone marrow:6.43

adipose:6.10

bone:-

skin:5.90

CAGE

cerebrum:5.62

cerebellum:-

brain stem:2.00

corpus callosum/glia:4.20

pineal gland:0.36

peripheral nerve:-

spine:2.79

retina:-

eye:-

artery/aorta:0

vein:1.39

lymphnode:0.81

peripheral blood:-

spleen:0.51

thymus:0.06

bone marrow:-

adipose:1.33

bone:-

skin:-

RNA-seq

cerebrum:6.44

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.14

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.02

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:5.90

placenta:6.29

prostate:5.61

ovary:5.75

testis:5.57

heart:6.65

muscle:7.30

esophagus:6.43

stomach:6.29

intestine:6.54

colon:6.41

liver/hepato:5.97

lung:6.05

bladder:-

kidney:6.28

pituitary:6.30

thyroid/parathyroid:5.87

adrenal gland:5.96

pancreas:6.54

breast:5.77

salivary:6.45

CAGE

uterus:2.02

placenta:0.16

prostate:1.64

ovary:0.89

testis:0.81

heart:2.28

muscle:4.40

esophagus:1.62

stomach:-

intestine:0.57

colon:0.86

liver/hepato:0

lung:0.14

bladder:1.80

kidney:0.49

pituitary:0.63

thyroid/parathyroid:0.67

adrenal gland:-

pancreas:0

breast:0

salivary:1.00

RNA-seq

uterus:-

placenta:-

prostate:1.46

ovary:0.41

testis:0.49

heart:1.42

muscle:2.69

esophagus:-

stomach:-

intestine:-

colon:0.46

liver/hepato:0.03

lung:0.19

bladder:-

kidney:0.39

pituitary:-

thyroid/parathyroid:0.77

adrenal gland:0.10

pancreas:-

breast:0.83

salivary:-

IDs

Refseq ID	NM_171825
Gene ID	815
Unigene ID	-
Probe set ID	213108_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000070808
GTEx ID	ENSG00000070808

Orthologous Gene

Mouse[2]	NM_009792, NM_177407
Rat[2]	NM_009792, NM_177407

Chromosomal Region

5q32 [149,599,054 - 149,669,854]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0006816	calcium ion transport
GO:0019221	cytokine-mediated signaling pathway
GO:0000082	G1/S transition of mitotic cell cycle
GO:0060333	interferon-gamma-mediated signaling pathway
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0046777	protein amino acid autophosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0048168	regulation of neuronal synaptic plasticity
GO:0046928	regulation of neurotransmitter secretion
GO:0007268	synaptic transmission

Cellular Component

GO:0030054	cell junction
GO:0005829	cytosol
GO:0030666	endocytic vesicle membrane
GO:0005654	nucleoplasm
GO:0005886	plasma membrane
GO:0042734	presynaptic membrane

Molecular Function

GO:0005524	ATP binding
GO:0005516	calmodulin binding
GO:0004683	calmodulin-dependent protein kinase activity
GO:0035254	glutamate receptor binding
GO:0016301	kinase activity
GO:0005515	protein binding

calcium/calmodulin-dependent protein kinase II alpha

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function