iron-sulfur cluster assembly 1 homolog (S. cerevisiae)

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Synonym

Iron sulfur assembly protein IscA, GK004, hIscA, MGC4276, HESB like domain containing 2, RP11-507D14.2, HBLD2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:246.50 cerebellum:12.60 brain stem:- corpus callosum/glia:437.40 pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:82.30 artery/aorta:119.90 vein:133.30 lymphnode:212.30 peripheral blood:200.40 spleen:56.70 thymus:51.50 bone marrow:19.70 adipose:605 bone:89.60 skin:33.60
GeneChip cerebrum:6.17 cerebellum:6 brain stem:6.41 corpus callosum/glia:5.80 pineal gland:- peripheral nerve:6.35 spine:6.09 retina:- eye:- artery/aorta:5.72 vein:5.82 lymphnode:5.39 peripheral blood:- spleen:5.48 thymus:5.92 bone marrow:7.33 adipose:6.08 bone:- skin:5.77
CAGE cerebrum:0.72 cerebellum:- brain stem:0.86 corpus callosum/glia:0.66 pineal gland:0.83 peripheral nerve:- spine:0.84 retina:- eye:- artery/aorta:0.34 vein:0.34 lymphnode:0.15 peripheral blood:- spleen:0.56 thymus:0.42 bone marrow:- adipose:0.46 bone:- skin:-
RNA-seq cerebrum:5.09 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:4.15 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.88 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:63.80 placenta:80.10 prostate:56.30 ovary:- testis:51.90 heart:76.60 muscle:40.20 esophagus:342.80 stomach:63.70 intestine:64.80 colon:178.10     liver/hepato:-        lung:102.60    bladder:628.10 kidney:166.40 pituitary:- thyroid/parathyroid:163.70 adrenal gland:152.40 pancreas:71.10 breast:27.90 salivary:-
GeneChip uterus:6 placenta:6.26 prostate:6.02 ovary:6.20 testis:8.19 heart:6.79 muscle:7.50 esophagus:5.98 stomach:5.82 intestine:6.32 colon:6.06 liver/hepato:5.93 lung:5.59 bladder:- kidney:6.14 pituitary:5.90 thyroid/parathyroid:5.60 adrenal gland:5.97 pancreas:6.13 breast:5.77 salivary:5.68
CAGE uterus:0.13 placenta:0.37 prostate:0.27 ovary:0.26 testis:1.27 heart:0.61 muscle:0.55 esophagus:0.26 stomach:- intestine:0.61 colon:0.12     liver/hepato:0.71    lung:0.40 bladder:0 kidney:0.39 pituitary:1.00 thyroid/parathyroid:0.23 adrenal gland:- pancreas:0.58 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:4.71 ovary:4.02 testis:4.52 heart:5.33 muscle:3.62 esophagus:- stomach:- intestine:- colon:4.27     liver/hepato:4.23        lung:3.71    bladder:- kidney:5.04 pituitary:- thyroid/parathyroid:4.65 adrenal gland:4.06 pancreas:- breast:5.07 salivary:-

Gene Information

IDs

Refseq ID NM_030940
Gene ID 81689
Unigene ID Hs.449291
Probe set ID 221425_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000135070
GTEx ID ENSG00000135070

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

9q21.33  [88,879,461  -  88,897,676]

Gene Family (Interpro ID)

IPR016092  FeS cluster insertion

Link to Pubmed  (Pubmed ID)

8125298
8619474
9110174
12477932
14702039
15164053
15262227
15489334
19322201
19656490
19864422
20186120
20302570
20877624
22323289
24217246
24733926

Gene Ontology  (GO ID)

Biological Process

GO:0016226  iron-sulfur cluster assembly

Cellular Component

GO:0005739  mitochondrion

Molecular Function

GO:0051536  iron-sulfur cluster binding
GO:0046872  metal ion binding
GO:0005198  structural molecule activity