cell division cycle 7 homolog (S. cerevisiae)

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Synonym

MGC126237, Cell division cycle 7-related protein kinase, CDC7-related kinase, CDC7L1, CDC7, CDC7 cell division cycle 7 (S. cerevisiae), huCDC7, HsCdc7, MGC126238, HsCDC7, huCdc7, Hsk1, MGC117361

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:88.20 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:17.60 artery/aorta:- vein:- lymphnode:40.40 peripheral blood:18.20 spleen:- thymus:77.30 bone marrow:- adipose:- bone:- skin:14.40
GeneChip cerebrum:4.34 cerebellum:5.63 brain stem:4.07 corpus callosum/glia:3.63 pineal gland:- peripheral nerve:3.66 spine:4.02 retina:- eye:- artery/aorta:3.42 vein:3.32 lymphnode:4.70 peripheral blood:- spleen:5.46 thymus:5.92 bone marrow:5.99 adipose:3.62 bone:- skin:3.84
CAGE cerebrum:2.46 cerebellum:- brain stem:1.96 corpus callosum/glia:1.27 pineal gland:2.79 peripheral nerve:- spine:2.41 retina:- eye:- artery/aorta:1.22 vein:1.76 lymphnode:2.15 peripheral blood:- spleen:2.44 thymus:3.06 bone marrow:- adipose:1.63 bone:- skin:-
RNA-seq cerebrum:1.91 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.04 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:14.60 prostate:- ovary:- testis:60.60 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:21.10        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:27.90 salivary:-
GeneChip uterus:3.90 placenta:5.25 prostate:3.61 ovary:3.90 testis:6.57 heart:3.27 muscle:3.09 esophagus:3.73 stomach:3.64 intestine:3.81 colon:3.71 liver/hepato:3.18 lung:4.15 bladder:- kidney:3.27 pituitary:4.34 thyroid/parathyroid:3.46 adrenal gland:3.70 pancreas:3.93 breast:3.79 salivary:3.10
CAGE uterus:1.26 placenta:2.14 prostate:1.21 ovary:1.86 testis:3.24 heart:1.21 muscle:0.38 esophagus:1.59 stomach:- intestine:1.63 colon:1.64     liver/hepato:1.29    lung:1.88 bladder:0.83 kidney:1.57 pituitary:2.77 thyroid/parathyroid:1.45 adrenal gland:- pancreas:0.94 breast:2.02 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.88 ovary:2.39 testis:1.72 heart:0.50 muscle:0.10 esophagus:- stomach:- intestine:- colon:0.83     liver/hepato:0.25        lung:0.00    bladder:- kidney:0.68 pituitary:- thyroid/parathyroid:0.81 adrenal gland:1.78 pancreas:- breast:0.75 salivary:-

Gene Information

IDs

Refseq ID NM_001134419
Gene ID 8317
Unigene ID Hs.533573
Probe set ID 204510_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000097046
GTEx ID ENSG00000097046

Orthologous Gene

Mouse[2]  NM_009863
Rat[1]  NM_001108352

Chromosomal Region

1p22.2  [91,966,404  -  91,991,321]

Gene Family (Interpro ID)

IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

8889549
9250678
9405610
9573348
10373557
10523313
10846177
11568184
12065429
12477932
12614612
12791985
15226314
15232106
15466207
15474462
15489334
15668232
15707391
16082200
16344560
16446360
16710414
16826239
16864800
16899510
16912045
16954377
17046832
17062569
17102137
17711849
17927916
18084324
18286467
18625709
18714392
19054765
19111665
19278428
19318489
19426592
19647517
19864417
19896697
20421204
20548946
20647475
20707412
20819778
21098111
21139048
21307088
21536671
21832049
21906983
21963094
21988832
22528513
22574151
22806309
23066029
23598722
23684929
23716994
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0051301  cell division
GO:0006260  DNA replication
GO:0000082  G1/S transition of mitotic cell cycle
GO:0000278  mitotic cell cycle
GO:0008284  positive regulation of cell proliferation
GO:0033261  regulation of S phase

Cellular Component

GO:0005737  cytoplasm
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0046872  metal ion binding
GO:0004674  protein serine/threonine kinase activity