frizzled homolog 7 (Drosophila)

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Synonym

hFz7, Fz-7, FzE3, FZD7, frizzled (Drosophila) homolog 7, Frizzled-7 precursor, frizzled homolog 7 (Drosophila)

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:29.40 artery/aorta:30 vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:25.60 skin:48
GeneChip cerebrum:4.49 cerebellum:8.64 brain stem:4.46 corpus callosum/glia:5.08 pineal gland:- peripheral nerve:7.64 spine:5.57 retina:- eye:- artery/aorta:6.88 vein:6.81 lymphnode:5.68 peripheral blood:- spleen:5.01 thymus:3.92 bone marrow:4.16 adipose:6.54 bone:- skin:6.58
CAGE cerebrum:0.28 cerebellum:- brain stem:0.03 corpus callosum/glia:0.24 pineal gland:0.21 peripheral nerve:- spine:0.22 retina:- eye:- artery/aorta:0.59 vein:0 lymphnode:0.42 peripheral blood:- spleen:0.17 thymus:0 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:1.31 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.76 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.19 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:21.90 prostate:22.50 ovary:111.80 testis:8.70 heart:25.50 muscle:20.10 esophagus:- stomach:- intestine:32.40 colon:8.50     liver/hepato:21.10        lung:34.20    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:74.30 salivary:-
GeneChip uterus:7.21 placenta:6.63 prostate:7.83 ovary:8.19 testis:4.77 heart:7.32 muscle:7.74 esophagus:6.59 stomach:6.92 intestine:6.99 colon:7.52 liver/hepato:3.94 lung:6.07 bladder:- kidney:5.87 pituitary:6.61 thyroid/parathyroid:6.13 adrenal gland:5.74 pancreas:3.70 breast:8.13 salivary:7.83
CAGE uterus:1.05 placenta:0.08 prostate:1.32 ovary:1.16 testis:0.33 heart:0.07 muscle:0.34 esophagus:1.01 stomach:- intestine:0.43 colon:1.10     liver/hepato:0    lung:0.31 bladder:1.47 kidney:0.39 pituitary:0 thyroid/parathyroid:0.23 adrenal gland:- pancreas:0 breast:0.55 salivary:0.83
RNA-seq uterus:- placenta:- prostate:5.48 ovary:4.61 testis:3.04 heart:2.48 muscle:2.56 esophagus:- stomach:- intestine:- colon:4.41     liver/hepato:0.37        lung:2.01    bladder:- kidney:3.09 pituitary:- thyroid/parathyroid:2.93 adrenal gland:2.81 pancreas:- breast:3.93 salivary:-

Gene Information

IDs

Refseq ID NM_003507
Gene ID 8324
Unigene ID Hs.173859
Probe set ID 203706_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000155760
GTEx ID ENSG00000155760

Orthologous Gene

Mouse[2]  NM_008057
Rat[2]  NM_008057

Chromosomal Region

2q33.1  [202,899,310  -  202,903,160]

Gene Family (Interpro ID)

IPR000539  Frizzled protein
IPR020067  Frizzled-like domain
IPR017981  GPCR, family 2-like

Link to Pubmed  (Pubmed ID)

9192640
9707618
9813155
11256614
12067714
12477932
15195140
15370539
15489334
15901282
16189514
16713569
17016432
17716656
18156211
18215320
18256285
18313787
18592008
18676680
18681827
18951430
18978678
19170196
19188438
19388021
19453261
19543507
19625176
19655379
19692168
19773752
20634891
21139048
21314951
21532620
21906983
24474766

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0007420  brain development
GO:0071300  cellular response to retinoic acid
GO:0007199  G-protein signaling, coupled to cGMP nucleotide second messenger
GO:0008406  gonad development
GO:0060231  mesenchymal to epithelial transition
GO:0010812  negative regulation of cell-substrate adhesion
GO:0042666  negative regulation of ectodermal cell fate specification
GO:0030182  neuron differentiation
GO:0060054  positive regulation of epithelial cell proliferation involved in wound healing
GO:0046330  positive regulation of JNK cascade
GO:0042327  positive regulation of phosphorylation
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0006355  regulation of transcription, DNA-dependent
GO:0014834  satellite cell maintenance involved in skeletal muscle regeneration
GO:0048103  somatic stem cell division
GO:0019827  stem cell maintenance
GO:0034446  substrate adhesion-dependent cell spreading
GO:0033077  T cell differentiation in the thymus
GO:0001944  vasculature development
GO:0060070  Wnt receptor signaling pathway through beta-catenin
GO:0007223  Wnt receptor signaling pathway, calcium modulating pathway

Cellular Component

GO:0045177  apical part of cell
GO:0005737  cytoplasm
GO:0016021  integral to membrane
GO:0032589  neuron projection membrane
GO:0005886  plasma membrane

Molecular Function

GO:0004930  G-protein coupled receptor activity
GO:0030165  PDZ domain binding
GO:0042813  Wnt receptor activity
GO:0017147  Wnt-protein binding