deoxyhypusine hydroxylase/monooxygenase

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Synonym

HEAT-like repeat-containing protein 1, Deoxyhypusine hydroxylase, DOHH, HLRC1, Deoxyhypusine monooxygenase, HEAT-like (PBS lyase) repeat containing 1, deoxyhypusine hydroxylase/monooxygenase, hDOHH, MGC4293

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:18.20 spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:7.58 cerebellum:7.76 brain stem:7.43 corpus callosum/glia:8.47 pineal gland:- peripheral nerve:6.75 spine:7.51 retina:- eye:- artery/aorta:6.57 vein:7.23 lymphnode:7.01 peripheral blood:- spleen:6.79 thymus:6.37 bone marrow:6.71 adipose:6.66 bone:- skin:6.46
CAGE cerebrum:2.33 cerebellum:- brain stem:2.45 corpus callosum/glia:2.37 pineal gland:1.32 peripheral nerve:- spine:1.37 retina:- eye:- artery/aorta:1.75 vein:2.11 lymphnode:1.80 peripheral blood:- spleen:1.95 thymus:1.94 bone marrow:- adipose:1.86 bone:- skin:-
RNA-seq cerebrum:3.22 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.84 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.21 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:6.61 placenta:6.37 prostate:5.76 ovary:6.88 testis:6.41 heart:7 muscle:6.92 esophagus:7.17 stomach:6.89 intestine:6.81 colon:6.92 liver/hepato:6.90 lung:7.03 bladder:- kidney:6.94 pituitary:6.75 thyroid/parathyroid:6.84 adrenal gland:7 pancreas:6.98 breast:6.87 salivary:7.13
CAGE uterus:1.58 placenta:1.84 prostate:2.05 ovary:1.92 testis:1.66 heart:1.88 muscle:2.40 esophagus:1.85 stomach:- intestine:1.60 colon:1.71     liver/hepato:2.03    lung:1.82 bladder:1.75 kidney:2.16 pituitary:1.83 thyroid/parathyroid:1.66 adrenal gland:- pancreas:2.34 breast:1.53 salivary:1.82
RNA-seq uterus:- placenta:- prostate:2.13 ovary:1.77 testis:2.38 heart:1.34 muscle:2.30 esophagus:- stomach:- intestine:- colon:2.11     liver/hepato:1.74        lung:1.58    bladder:- kidney:2.62 pituitary:- thyroid/parathyroid:2.55 adrenal gland:2.81 pancreas:- breast:2.33 salivary:-

Gene Information

IDs

Refseq ID NM_031304
Gene ID 83475
Unigene ID Hs.609012
Probe set ID 208141_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000129932
GTEx ID ENSG00000129932

Orthologous Gene

Mouse[1]  NM_133964
Rat[1]  NM_001025006

Chromosomal Region

19p13.3  [3,490,820  -  3,500,938]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

12477932
15057824
15489334
16371467
16452303
16533814
17213197
17476569
19706422
21139048
22190034
22908221
22927971
23824909
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0044267  cellular protein metabolic process
GO:0008612  peptidyl-lysine modification to hypusine
GO:0043687  post-translational protein modification

Cellular Component

GO:0005575  cellular_component
GO:0005829  cytosol

Molecular Function

GO:0019135  deoxyhypusine monooxygenase activity
GO:0046872  metal ion binding
GO:0005515  protein binding