dynein, light chain, roadblock-type 1

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Synonym

HSPC162, BLP, BITH, DYNLRB1, Bithoraxoid-like protein, Dynein-associated protein Km23, DNLC2A, DNCL2A, Dynein light chain 2A, cytoplasmic, dynein, light chain, roadblock-type 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:3.60 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:890.10 peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:14.40
GeneChip cerebrum:9.89 cerebellum:9.52 brain stem:10.05 corpus callosum/glia:9.33 pineal gland:- peripheral nerve:10 spine:9.48 retina:- eye:- artery/aorta:9.45 vein:9.45 lymphnode:8.88 peripheral blood:- spleen:8.81 thymus:8.67 bone marrow:8.49 adipose:9.04 bone:- skin:9.49
CAGE cerebrum:6.26 cerebellum:- brain stem:6.00 corpus callosum/glia:5.88 pineal gland:6.29 peripheral nerve:- spine:5.84 retina:- eye:- artery/aorta:5.75 vein:5.37 lymphnode:5.25 peripheral blood:- spleen:5.50 thymus:5.25 bone marrow:- adipose:5.50 bone:- skin:-
RNA-seq cerebrum:7.76 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.76 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.90 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:25.50 prostate:- ovary:- testis:4.30 heart:- muscle:40.20 esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:- salivary:-
GeneChip uterus:9.28 placenta:9.41 prostate:9.82 ovary:9.53 testis:8.55 heart:9.07 muscle:8.93 esophagus:9.38 stomach:8.90 intestine:9.07 colon:9.34 liver/hepato:8.12 lung:9.34 bladder:- kidney:9.69 pituitary:9.35 thyroid/parathyroid:9.26 adrenal gland:9.19 pancreas:8.62 breast:9.34 salivary:9.09
CAGE uterus:5.62 placenta:5.85 prostate:5.69 ovary:5.46 testis:5.12 heart:5.63 muscle:5.78 esophagus:5.63 stomach:- intestine:5.44 colon:5.30     liver/hepato:5.30    lung:5.43 bladder:5.64 kidney:5.98 pituitary:5.82 thyroid/parathyroid:5.78 adrenal gland:- pancreas:5.14 breast:5.62 salivary:5.80
RNA-seq uterus:- placenta:- prostate:7.32 ovary:7.11 testis:6.79 heart:6.38 muscle:6.56 esophagus:- stomach:- intestine:- colon:7.20     liver/hepato:5.50        lung:6.96    bladder:- kidney:7.15 pituitary:- thyroid/parathyroid:7.06 adrenal gland:7.20 pancreas:- breast:6.95 salivary:-

Gene Information

IDs

Refseq ID NM_014183
Gene ID 83658
Unigene ID Hs.593920
Probe set ID 217917_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125971
GTEx ID ENSG00000125971

Orthologous Gene

Mouse[1]  NM_025947
Rat [0]  

Chromosomal Region

20q11.22  [33,104,214  -  33,128,762]

Gene Family (Interpro ID)

IPR016561  Dynein light chain, roadblock-type
IPR004942  Dynein light chain-related

Link to Pubmed  (Pubmed ID)

10198631
11042152
11750132
11780052
12077152
12475967
12477932
12629046
12665801
14702039
14733918
15231747
15489334
16189514
16260502
16778097
16950395
16970917
17556076
18044744
19571232
19711352
19946888
20360068
20972266
21139048
21145461
21890473
21906983
22505724
22637579
22863883
22939629
23000965
23079622
23333499
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0007018  microtubule-based movement
GO:0006810  transport
GO:0007632  visual behavior

Cellular Component

GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0005868  cytoplasmic dynein complex
GO:0005874  microtubule

Molecular Function

GO:0042802  identical protein binding
GO:0003777  microtubule motor activity
GO:0005515  protein binding