SET domain, bifurcated 2

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Synonym

DKFZp586I0123, CLLL8, Histone H3-K9 methyltransferase, H3-K9-HMTase, chromosome 13 open reading frame 4, C13orf4, DKFZp761J1217, SETDB2, CLLD8, SET domain, bifurcated 2, SET domain bifurcated 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:15.40 cerebellum:12.60 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:171.90 peripheral blood:36.40 spleen:18.90 thymus:38.70 bone marrow:- adipose:- bone:25.60 skin:14.40
GeneChip nodata
CAGE cerebrum:2.63 cerebellum:- brain stem:2.52 corpus callosum/glia:2.51 pineal gland:2.67 peripheral nerve:- spine:2.51 retina:- eye:- artery/aorta:2.30 vein:2.91 lymphnode:3.05 peripheral blood:- spleen:3.14 thymus:2.97 bone marrow:- adipose:2.65 bone:- skin:-
RNA-seq cerebrum:1.17 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.30 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.99 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:14.60 prostate:22.50 ovary:37.30 testis:69.20 heart:51.10 muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:52.80        lung:9.80    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:35.60 breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:2.95 placenta:2.08 prostate:2.97 ovary:2.78 testis:2.94 heart:2.70 muscle:1.44 esophagus:2.62 stomach:- intestine:2.34 colon:2.46     liver/hepato:2.39    lung:2.97 bladder:2.80 kidney:2.80 pituitary:2.92 thyroid/parathyroid:2.91 adrenal gland:- pancreas:2.34 breast:2.64 salivary:2.66
RNA-seq uterus:- placenta:- prostate:1.86 ovary:2.04 testis:2.44 heart:1.56 muscle:0.97 esophagus:- stomach:- intestine:- colon:1.65     liver/hepato:0.95        lung:1.24    bladder:- kidney:2.03 pituitary:- thyroid/parathyroid:2.09 adrenal gland:1.56 pancreas:- breast:1.19 salivary:-

Gene Information

IDs

Refseq ID NM_001160308
Gene ID 83852
Unigene ID Hs.631789
Probe set ID -
Ensembl ID ENSG00000136169
GTEx ID ENSG00000136169

Orthologous Gene

Mouse[1]  NM_001081024
Rat[1]  NM_001081024

Chromosomal Region

13q14.2  [50,018,429  -  50,069,138]

Gene Family (Interpro ID)

IPR016177  DNA-binding, integrase-type
IPR001739  Methyl-CpG DNA binding
IPR007728  Pre-SET domain
IPR003606  Pre-SET zinc-binding sub-group

Link to Pubmed  (Pubmed ID)

11306461
12477932
12754510
15057823
15489334
16344560
18498648
20085599
20404330
22797925

Gene Ontology  (GO ID)

Biological Process

GO:0051301  cell division
GO:0007059  chromosome segregation
GO:0001947  heart looping
GO:0051567  histone H3-K9 methylation
GO:0070986  left/right axis specification
GO:0007067  mitosis
GO:0045892  negative regulation of transcription, DNA-dependent

Cellular Component

GO:0005694  chromosome
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0046974  histone methyltransferase activity (H3-K9 specific)
GO:0008270  zinc ion binding