phosphatidylinositol-4-phosphate 5-kinase, type I, beta

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Synonym

PIP5KIbeta, Protein STM-7, PIP5K1B, STM7, PtdIns(4)P-5-kinase beta, MSS4

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:62.80 cerebellum:63 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:184 spine:- retina:- eye:141 artery/aorta:89.90 vein:- lymphnode:30.30 peripheral blood:18.20 spleen:132.30 thymus:- bone marrow:137.80 adipose:121 bone:64 skin:24
GeneChip cerebrum:5.72 cerebellum:7.77 brain stem:6.88 corpus callosum/glia:5.03 pineal gland:- peripheral nerve:5.72 spine:5.65 retina:- eye:- artery/aorta:5.98 vein:4.99 lymphnode:5.12 peripheral blood:- spleen:4.77 thymus:4.33 bone marrow:7.14 adipose:4.81 bone:- skin:4.54
CAGE cerebrum:3.10 cerebellum:- brain stem:2.55 corpus callosum/glia:2.65 pineal gland:1.99 peripheral nerve:- spine:2.43 retina:- eye:- artery/aorta:3.04 vein:2.46 lymphnode:2.17 peripheral blood:- spleen:2.44 thymus:0.77 bone marrow:- adipose:1.44 bone:- skin:-
RNA-seq cerebrum:3.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.43 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:154.90 placenta:94.70 prostate:112.60 ovary:111.80 testis:142.80 heart:114.90 muscle:80.40 esophagus:- stomach:254.90 intestine:97.20 colon:169.60     liver/hepato:42.20        lung:53.80    bladder:- kidney:104 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:8.90 breast:37.20 salivary:-
GeneChip uterus:5.67 placenta:5.97 prostate:5.10 ovary:4.96 testis:7.68 heart:6.67 muscle:4.60 esophagus:3.97 stomach:6.11 intestine:5.85 colon:6.22 liver/hepato:3.96 lung:6.35 bladder:- kidney:5.40 pituitary:5.69 thyroid/parathyroid:4.51 adrenal gland:5.99 pancreas:5.26 breast:4.72 salivary:6.88
CAGE uterus:2.70 placenta:3.81 prostate:2.58 ovary:1.93 testis:4.01 heart:3.74 muscle:1.70 esophagus:1.34 stomach:- intestine:4.71 colon:4.12     liver/hepato:0.14    lung:3.87 bladder:2.39 kidney:2.79 pituitary:3.14 thyroid/parathyroid:1.00 adrenal gland:- pancreas:2.71 breast:2.53 salivary:3.30
RNA-seq uterus:- placenta:- prostate:2.83 ovary:1.35 testis:4.28 heart:4.48 muscle:0.46 esophagus:- stomach:- intestine:- colon:2.91     liver/hepato:0.13        lung:2.48    bladder:- kidney:2.47 pituitary:- thyroid/parathyroid:0.83 adrenal gland:1.88 pancreas:- breast:1.43 salivary:-

Gene Information

IDs

Refseq ID NM_003558
Gene ID 8395
Unigene ID Hs.534371
Probe set ID 205632_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107242
GTEx ID ENSG00000107242

Orthologous Gene

Mouse[3]  NM_008846
Rat[1]  NM_001012743

Chromosomal Region

9q21.11  [71,320,575  -  71,624,092]

Gene Family (Interpro ID)

IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
IPR016034  Phosphatidylinositol-4-phosphate 5-kinase, core, subgroup

Link to Pubmed  (Pubmed ID)

7581382
8841185
8889548
8955136
9177790
12477932
14614850
14701839
15046600
15164053
15489334
17353931
18158329
19553680
19850283
20379614
20383146
20442317
20624912
21906983
23000965
23192594
23470693
23552101
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0006661  phosphatidylinositol biosynthetic process
GO:0006644  phospholipid metabolic process
GO:0016310  phosphorylation

Cellular Component

GO:0005829  cytosol
GO:0012505  endomembrane system
GO:0016020  membrane
GO:0001931  uropod

Molecular Function

GO:0016308  1-phosphatidylinositol-4-phosphate 5-kinase activity
GO:0005524  ATP binding
GO:0005515  protein binding