phospholipase A2, group VI (cytosolic, calcium-independent)

Synonym

GVI PLA2, PNPLA9, PLA2G6, INAD1, 85 kDa calcium-independent phospholipase A2, GVI, IPLA2, CaI-PLA2, iPLA2, Group VI phospholipase A2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:90.10

cerebellum:138.50

brain stem:-

corpus callosum/glia:58.30

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:88.20

artery/aorta:-

vein:-

lymphnode:50.60

peripheral blood:255.10

spleen:-

thymus:244.80

bone marrow:-

adipose:-

bone:-

skin:14.40

GeneChip

cerebrum:7.25

cerebellum:6.90

brain stem:7.25

corpus callosum/glia:7.53

pineal gland:-

peripheral nerve:7.03

spine:7.34

retina:-

eye:-

artery/aorta:7.09

vein:6.77

lymphnode:7.24

peripheral blood:-

spleen:7.06

thymus:7.41

bone marrow:7.26

adipose:7.26

bone:-

skin:7.27

CAGE

cerebrum:2.97

cerebellum:-

brain stem:3.17

corpus callosum/glia:3.78

pineal gland:3.55

peripheral nerve:-

spine:3.12

retina:-

eye:-

artery/aorta:2.15

vein:2.42

lymphnode:2.15

peripheral blood:-

spleen:1.96

thymus:2.80

bone marrow:-

adipose:2.69

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:127.60

placenta:25.50

prostate:45.10

ovary:74.50

testis:225

heart:-

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:33.90

liver/hepato:10.60

lung:58.70

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:101.60

pancreas:35.60

breast:18.60

salivary:-

GeneChip

uterus:6.97

placenta:6.77

prostate:7.24

ovary:7.01

testis:8.14

heart:7.08

muscle:6.95

esophagus:7.22

stomach:7

intestine:7.03

colon:6.97

liver/hepato:6.94

lung:6.98

bladder:-

kidney:7.31

pituitary:7.17

thyroid/parathyroid:7.73

adrenal gland:7.25

pancreas:7.48

breast:7.15

salivary:7.67

CAGE

uterus:2.57

placenta:1.25

prostate:2.40

ovary:1.98

testis:3.70

heart:1.69

muscle:1.85

esophagus:1.98

stomach:-

intestine:2.82

colon:2.28

liver/hepato:1.07

lung:2.05

bladder:1.80

kidney:2.00

pituitary:2.67

thyroid/parathyroid:2.61

adrenal gland:-

pancreas:2.18

breast:2.87

salivary:2.35

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.00

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_001004426
Gene ID	8398
Unigene ID	Hs.170479
Probe set ID	204691_x_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000184381
GTEx ID	ENSG00000184381

Orthologous Gene

Mouse[1]	NM_001199023, NM_001199024, NM_001199025, NM_016915
Rat [0]

Chromosomal Region

22q13.1 [38,507,502 - 38,588,107]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0032049	cardiolipin biosynthetic process
GO:0008219	cell death
GO:0006935	chemotaxis
GO:0007204	elevation of cytosolic calcium ion concentration
GO:0046474	glycerophospholipid biosynthetic process
GO:0045087	innate immune response
GO:0016042	lipid catabolic process
GO:0060135	maternal process involved in female pregnancy
GO:0007613	memory
GO:0051967	negative regulation of synaptic transmission, glutamatergic
GO:0006644	phospholipid metabolic process
GO:0045921	positive regulation of exocytosis
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0090037	positive regulation of protein kinase C signaling cascade
GO:0090200	positive regulation of release of cytochrome c from mitochondria
GO:0045909	positive regulation of vasodilation
GO:0034976	response to endoplasmic reticulum stress
GO:0014832	urinary bladder smooth muscle contraction

Cellular Component

GO:0005813	centrosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0016020	membrane
GO:0005739	mitochondrion

Molecular Function

GO:0043008	ATP-dependent protein binding
GO:0047499	calcium-independent phospholipase A2 activity
GO:0005516	calmodulin binding
GO:0004623	phospholipase A2 activity

phospholipase A2, group VI (cytosolic, calcium-independent)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function