caspase 7, apoptosis-related cysteine peptidase

Synonym

CASP-7, caspase 7, apoptosis-related cysteine peptidase, ICE-LAP3, CMH-1, Caspase-7 precursor, CASP7, Apoptotic protease Mch-3, ICE-like apoptotic protease 3, MCH3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:29.60

cerebellum:-

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:61.30

spine:-

retina:-

eye:17.60

artery/aorta:389.70

vein:-

lymphnode:20.20

peripheral blood:36.40

spleen:132.30

thymus:90.20

bone marrow:-

adipose:40.30

bone:38.40

skin:110.40

GeneChip

cerebrum:4.64

cerebellum:4.33

brain stem:4.44

corpus callosum/glia:4.80

pineal gland:-

peripheral nerve:5.45

spine:4.82

retina:-

eye:-

artery/aorta:6.21

vein:6.06

lymphnode:6.07

peripheral blood:-

spleen:6.74

thymus:6.76

bone marrow:5.44

adipose:6.31

bone:-

skin:6.19

CAGE

cerebrum:2.31

cerebellum:-

brain stem:2.10

corpus callosum/glia:2.44

pineal gland:2.54

peripheral nerve:-

spine:2.87

retina:-

eye:-

artery/aorta:3.09

vein:2.98

lymphnode:3.06

peripheral blood:-

spleen:3.08

thymus:2.90

bone marrow:-

adipose:3.44

bone:-

skin:-

RNA-seq

cerebrum:0.23

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.45

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:54.70

placenta:51

prostate:90.10

ovary:74.50

testis:17.30

heart:38.30

muscle:20.10

esophagus:-

stomach:21.20

intestine:97.20

colon:50.90

liver/hepato:31.70

lung:73.30

bladder:502.40

kidney:83.20

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:8.90

breast:18.60

salivary:-

GeneChip

uterus:6.56

placenta:6.07

prostate:6.98

ovary:6.65

testis:4.94

heart:5.69

muscle:5.84

esophagus:5.89

stomach:6.72

intestine:6.93

colon:7.49

liver/hepato:6.03

lung:6.88

bladder:-

kidney:6.01

pituitary:5.19

thyroid/parathyroid:5.95

adrenal gland:5.69

pancreas:5.76

breast:6.50

salivary:7.72

CAGE

uterus:3.21

placenta:2.83

prostate:3.10

ovary:2.97

testis:2.31

heart:3.04

muscle:2.77

esophagus:3.08

stomach:-

intestine:4.69

colon:4.05

liver/hepato:3.12

lung:3.28

bladder:2.97

kidney:3.16

pituitary:2.79

thyroid/parathyroid:2.59

adrenal gland:-

pancreas:3.40

breast:3.67

salivary:3.74

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.00

testis:0.80

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.00

liver/hepato:0.00

lung:0.45

bladder:-

kidney:0.67

pituitary:-

thyroid/parathyroid:0.49

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_033338
Gene ID	840
Unigene ID	Hs.9216
Probe set ID	207181_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000165806
GTEx ID	ENSG00000165806

Orthologous Gene

Mouse[2]	NM_007611
Rat [0]

Chromosomal Region

10q25.3 [115,438,942 - 115,490,662]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR011600	Peptidase C14, caspase catalytic
IPR015917	Peptidase C14, caspase precursor p45, core

GO:0008635	activation of caspase activity by cytochrome c
GO:0006915	apoptosis
GO:0006921	cell structure disassembly during apoptosis
GO:0007507	heart development
GO:0006917	induction of apoptosis
GO:0043525	positive regulation of neuron apoptosis
GO:0016485	protein processing
GO:0006508	proteolysis
GO:0001836	release of cytochrome c from mitochondria
GO:0009411	response to UV

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005654	nucleoplasm
GO:0005634	nucleus

GO:0004190	aspartic-type endopeptidase activity
GO:0004197	cysteine-type endopeptidase activity
GO:0008234	cysteine-type peptidase activity
GO:0005515	protein binding

caspase 7, apoptosis-related cysteine peptidase

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function