NLR family, CARD domain containing 5

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Synonym

nucleotide-binding oligomerization domains 27, FLJ39711, NOD27, FLJ21709

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:11.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:- eye:- artery/aorta:- vein:666.50 lymphnode:121.30 peripheral blood:36.40 spleen:170.20 thymus:38.70 bone marrow:177.10 adipose:- bone:115.20 skin:28.80
GeneChip nodata
CAGE cerebrum:2.05 cerebellum:- brain stem:2.48 corpus callosum/glia:2.40 pineal gland:2.60 peripheral nerve:- spine:2.95 retina:- eye:- artery/aorta:2.99 vein:3.80 lymphnode:3.98 peripheral blood:- spleen:3.69 thymus:2.91 bone marrow:- adipose:3.21 bone:- skin:-
RNA-seq cerebrum:0.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.52 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.70 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:14.60 prostate:22.50 ovary:74.50 testis:13 heart:38.30 muscle:- esophagus:- stomach:233.70 intestine:64.80 colon:84.80     liver/hepato:31.70        lung:78.20    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:8.90 breast:46.50 salivary:-
GeneChip nodata
CAGE uterus:2.99 placenta:1.74 prostate:2.64 ovary:2.33 testis:1.63 heart:2.53 muscle:2.28 esophagus:2.51 stomach:- intestine:2.67 colon:3.11     liver/hepato:2.41    lung:3.37 bladder:2.48 kidney:2.03 pituitary:3.71 thyroid/parathyroid:2.35 adrenal gland:- pancreas:1.59 breast:2.47 salivary:2.72
RNA-seq uterus:- placenta:- prostate:1.68 ovary:1.53 testis:0.47 heart:0.78 muscle:0.25 esophagus:- stomach:- intestine:- colon:0.68     liver/hepato:0.94        lung:2.87    bladder:- kidney:1.05 pituitary:- thyroid/parathyroid:0.94 adrenal gland:3.32 pancreas:- breast:1.37 salivary:-

Gene Information

IDs

Refseq ID NM_032206
Gene ID 84166
Unigene ID Hs.528836
Probe set ID -
Ensembl ID ENSG00000140853
GTEx ID ENSG00000140853

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

16q13  [57,023,397  -  57,117,443]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10737800
12477932
12615073
14702039
16344560
20061403
20434986
20538593
20571754
20610642
20639463
21191067
21347282
22024701
22082156
22310711
22412192
22490867
22490869
22505724
22688191
23212062
23505323
23815151
24044430
24815518

Gene Ontology  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0045087  innate immune response
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0032480  negative regulation of type I interferon production
GO:0060339  negative regulation of type I interferon-mediated signaling pathway
GO:0060335  positive regulation of interferon-gamma-mediated signaling pathway
GO:0045345  positive regulation of MHC class I biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0060340  positive regulation of type I interferon-mediated signaling pathway
GO:0043549  regulation of kinase activity

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005634  nucleus

Molecular Function

GO:0005524  ATP binding
GO:0005515  protein binding