latent transforming growth factor beta binding protein 4

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Synonym

LTBP4, LTBP-4L, LTBP-4, FLJ90018, FLJ46318

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:56.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:429.40 spine:112.30 retina:- eye:152.80 artery/aorta:30 vein:- lymphnode:101.10 peripheral blood:109.30 spleen:94.50 thymus:193.30 bone marrow:19.70 adipose:121 bone:191.90 skin:62.40
GeneChip cerebrum:5.52 cerebellum:6.02 brain stem:5.54 corpus callosum/glia:5.73 pineal gland:- peripheral nerve:8.52 spine:5.94 retina:- eye:- artery/aorta:9.09 vein:8.13 lymphnode:7.09 peripheral blood:- spleen:7.46 thymus:5.48 bone marrow:5.64 adipose:7.92 bone:- skin:6.87
CAGE cerebrum:2.19 cerebellum:- brain stem:3.40 corpus callosum/glia:2.89 pineal gland:2.76 peripheral nerve:- spine:3.80 retina:- eye:- artery/aorta:6.07 vein:5.04 lymphnode:4.15 peripheral blood:- spleen:3.86 thymus:2.98 bone marrow:- adipose:4.18 bone:- skin:-
RNA-seq cerebrum:1.45 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.81 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:182.30 placenta:40.10 prostate:169 ovary:559 testis:108.20 heart:217.10 muscle:80.40 esophagus:- stomach:212.40 intestine:226.80 colon:101.80     liver/hepato:-        lung:190.60    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:167.30 salivary:-
GeneChip uterus:8.20 placenta:5.45 prostate:7.24 ovary:7.62 testis:7.05 heart:7.59 muscle:6.50 esophagus:7.78 stomach:7.61 intestine:7.09 colon:7.62 liver/hepato:6.23 lung:8.38 bladder:- kidney:6.34 pituitary:6.53 thyroid/parathyroid:8.53 adrenal gland:7.37 pancreas:5.95 breast:7.28 salivary:6.51
CAGE uterus:5.63 placenta:3.20 prostate:5.76 ovary:5.19 testis:4.93 heart:5.34 muscle:3.79 esophagus:5.09 stomach:- intestine:4.69 colon:5.11     liver/hepato:3.24    lung:5.34 bladder:5.17 kidney:3.39 pituitary:3.30 thyroid/parathyroid:4.48 adrenal gland:- pancreas:2.66 breast:4.13 salivary:3.59
RNA-seq uterus:- placenta:- prostate:5.27 ovary:5.30 testis:6.28 heart:3.92 muscle:2.74 esophagus:- stomach:- intestine:- colon:5.46     liver/hepato:1.51        lung:6.35    bladder:- kidney:3.17 pituitary:- thyroid/parathyroid:4.79 adrenal gland:4.26 pancreas:- breast:4.69 salivary:-

Gene Information

IDs

Refseq ID NM_001042545
Gene ID 8425
Unigene ID Hs.466766
Probe set ID 204442_x_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000090006
GTEx ID ENSG00000090006

Orthologous Gene

Mouse[2]  NM_001113549, NM_175641
Rat[2]  NM_001113549, NM_175641

Chromosomal Region

19q13.2  [41,099,072  -  41,135,725]

Gene Family (Interpro ID)

IPR001881  EGF-like calcium-binding
IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

9271198
9660815
10930463
11104663
11683420
16157329
16456143
16713569
18276110
18487557
18585707
18654987
18985028
19836010
19897194
19913121
19998449
20175115
20424473
20587546
20628086
20800603
21078624
21468687
21505857
21963094
21988832
22268729
22558309
22829427
23440719
23741501

Gene Ontology  (GO ID)

Biological Process

GO:0030198  extracellular matrix organization
GO:0030252  growth hormone secretion
GO:0007275  multicellular organismal development
GO:0006457  protein folding
GO:0045595  regulation of cell differentiation
GO:0001558  regulation of cell growth
GO:0030162  regulation of proteolysis
GO:0017015  regulation of transforming growth factor beta receptor signaling pathway
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0031012  extracellular matrix
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0005509  calcium ion binding
GO:0005539  glycosaminoglycan binding
GO:0005178  integrin binding
GO:0005515  protein binding
GO:0050431  transforming growth factor beta binding
GO:0005024  transforming growth factor beta receptor activity