HOP homeobox

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Synonym

SMAP31, OB1, MGC20820, homeodomain-only protein, Toto, NECC1, LAGY, Cameo

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:8.47 cerebellum:7.15 brain stem:8.51 corpus callosum/glia:7.15 pineal gland:- peripheral nerve:6.71 spine:9.24 retina:- eye:- artery/aorta:5.39 vein:8.23 lymphnode:8.14 peripheral blood:- spleen:6.85 thymus:6.42 bone marrow:5.26 adipose:6.19 bone:- skin:10.82
CAGE cerebrum:4.15 cerebellum:- brain stem:3.60 corpus callosum/glia:3.30 pineal gland:2.54 peripheral nerve:- spine:4.26 retina:- eye:- artery/aorta:1.79 vein:2.09 lymphnode:4.16 peripheral blood:- spleen:1.58 thymus:2.47 bone marrow:- adipose:1.01 bone:- skin:-
RNA-seq cerebrum:3.55 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.03 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:7.63 placenta:11.59 prostate:7.04 ovary:7.27 testis:8.75 heart:6.53 muscle:6.46 esophagus:11.72 stomach:6.50 intestine:7.32 colon:5.78 liver/hepato:5.25 lung:10.57 bladder:- kidney:5.48 pituitary:5.44 thyroid/parathyroid:9.95 adrenal gland:7.62 pancreas:5.38 breast:7.35 salivary:6.70
CAGE uterus:3.81 placenta:6.63 prostate:2.88 ovary:2.53 testis:4.37 heart:2.50 muscle:1.84 esophagus:6.24 stomach:- intestine:3.16 colon:2.94     liver/hepato:0.96    lung:6.43 bladder:3.14 kidney:1.87 pituitary:1.49 thyroid/parathyroid:5.98 adrenal gland:- pancreas:0.58 breast:1.16 salivary:2.99
RNA-seq uterus:- placenta:- prostate:0 ovary:0.07 testis:0.78 heart:0.65 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:4.14    bladder:- kidney:0 pituitary:- thyroid/parathyroid:3.23 adrenal gland:0.00 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_139212
Gene ID 84525
Unigene ID -
Probe set ID 211597_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000171476
GTEx ID ENSG00000171476

Orthologous Gene

Mouse[12]  NM_001159900, NM_001159901, NM_175606
Rat[1]  NM_133621, NM_001159901, NM_175606

Chromosomal Region

4q12  [57,514,155  -  57,548,065]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

11076863
12297045
12477932
12573257
12759545
12975471
14516659
14522464
14532270
14702039
15213722
15307938
15381369
15457851
15489334
15489336
16344560
16381901
16939210
17192267
17498662
17576768
18052042
18234960
18507846
19173292
20211142
20226564
20228841
21061432
21256618
21382376
21700222
22824801
22904674
23036489
23707782

Gene Ontology  (GO ID)

Biological Process

GO:0045596  negative regulation of cell differentiation
GO:0006351  transcription, DNA-dependent
GO:0001829  trophectodermal cell differentiation

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0043565  sequence-specific DNA binding
GO:0003700  transcription factor activity