cullin 2

jump to detail

Synonym

CUL-2, MGC131970, cullin 2, Cullin-2, CUL2

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:65.20

cerebellum:25.20

brain stem:-

corpus callosum/glia:145.80

pineal gland:-

peripheral nerve:92

spine:112.30

retina:-

eye:35.30

artery/aorta:89.90

vein:-

lymphnode:30.30

peripheral blood:91.10

spleen:-

thymus:38.70

bone marrow:19.70

adipose:40.30

bone:64

skin:48

GeneChip

cerebrum:6.77

cerebellum:6.72

brain stem:6.96

corpus callosum/glia:6.57

pineal gland:-

peripheral nerve:6.96

spine:6.63

retina:-

eye:-

artery/aorta:6.53

vein:6.50

lymphnode:6.77

peripheral blood:-

spleen:6.85

thymus:7.12

bone marrow:6.14

adipose:6.68

bone:-

skin:6.62

CAGE

cerebrum:3.52

cerebellum:-

brain stem:3.58

corpus callosum/glia:3.08

pineal gland:4.03

peripheral nerve:-

spine:3.41

retina:-

eye:-

artery/aorta:3.05

vein:3.43

lymphnode:3.24

peripheral blood:-

spleen:3.54

thymus:3.62

bone marrow:-

adipose:3.64

bone:-

skin:-

RNA-seq

cerebrum:0.83

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.54

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.80

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:91.10

placenta:43.70

prostate:45.10

ovary:37.30

testis:168.70

heart:38.30

muscle:60.30

esophagus:-

stomach:63.70

intestine:97.20

colon:25.40

liver/hepato:52.80

lung:19.60

bladder:376.80

kidney:41.60

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:83.60

salivary:-

GeneChip

uterus:7

placenta:7.01

prostate:7.03

ovary:6.83

testis:7.92

heart:6.54

muscle:7.60

esophagus:6.94

stomach:6.44

intestine:6.49

colon:5.77

liver/hepato:6.39

lung:6.78

bladder:-

kidney:5.92

pituitary:6.39

thyroid/parathyroid:6.45

adrenal gland:6.37

pancreas:5.93

breast:6.60

salivary:5.98

CAGE

uterus:3.41

placenta:3.84

prostate:3.35

ovary:3.42

testis:3.60

heart:3.38

muscle:3.50

esophagus:3.46

stomach:-

intestine:3.21

colon:2.83

liver/hepato:3.37

lung:3.25

bladder:3.59

kidney:3.20

pituitary:3.62

thyroid/parathyroid:3.17

adrenal gland:-

pancreas:3.13

breast:3.40

salivary:3.09

RNA-seq

uterus:-

placenta:-

prostate:1.93

ovary:2.27

testis:1.26

heart:0.87

muscle:1.60

esophagus:-

stomach:-

intestine:-

colon:2.49

liver/hepato:0.71

lung:0.35

bladder:-

kidney:0.89

pituitary:-

thyroid/parathyroid:2.29

adrenal gland:1.53

pancreas:-

breast:0.63

salivary:-

IDs

Refseq ID	NM_003591
Gene ID	8453
Unigene ID	Hs.82919
Probe set ID	203079_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000108094
GTEx ID	ENSG00000108094

Orthologous Gene

Mouse[2]	NM_029402
Rat[1]	NM_001108417

Chromosomal Region

10p11.21 [35,297,479 - 35,379,570]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR019559	Cullin protein, neddylation domain
IPR011991	Winged helix repressor DNA-binding

Gene Ontology (GO ID)

Biological Process

GO:0007050	cell cycle arrest
GO:0071456	cellular response to hypoxia
GO:0000082	G1/S transition of mitotic cell cycle
GO:0008285	negative regulation of cell proliferation
GO:0016567	protein ubiquitination
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0019048	virus-host interaction

Cellular Component

GO:0031462	Cul2-RING ubiquitin ligase complex
GO:0005829	cytosol
GO:0005654	nucleoplasm

Molecular Function

GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding

cullin 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function