cold shock domain protein A

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Synonym

DNA-binding protein A, DBPA, CSDA1, Cold shock domain-containing protein A, Single-strand DNA-binding protein NF-GMB, dbpA, CSDA, ZONAB, cold shock domain protein A

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:37.90 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:245.40 spine:112.30 retina:237.30 eye:370.30 artery/aorta:179.90 vein:266.60 lymphnode:141.50 peripheral blood:18.20 spleen:37.80 thymus:90.20 bone marrow:944.70 adipose:161.30 bone:102.40 skin:148.80
GeneChip cerebrum:6 cerebellum:5.07 brain stem:6.26 corpus callosum/glia:6.21 pineal gland:- peripheral nerve:8.25 spine:7.05 retina:- eye:- artery/aorta:8.98 vein:9.28 lymphnode:8.10 peripheral blood:- spleen:8.22 thymus:7.94 bone marrow:9.75 adipose:9.15 bone:- skin:9.95
CAGE cerebrum:2.89 cerebellum:- brain stem:3.54 corpus callosum/glia:3.14 pineal gland:3.37 peripheral nerve:- spine:4.34 retina:- eye:- artery/aorta:5.10 vein:4.80 lymphnode:4.66 peripheral blood:- spleen:4.57 thymus:3.77 bone marrow:- adipose:5.64 bone:- skin:-
RNA-seq cerebrum:3.53 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.36 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.63 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:72.90 placenta:87.40 prostate:90.10 ovary:- testis:268.20 heart:255.40 muscle:1547 esophagus:- stomach:63.70 intestine:97.20 colon:118.70     liver/hepato:168.90        lung:127.10    bladder:- kidney:124.80 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:186.70 breast:130.10 salivary:-
GeneChip uterus:8.89 placenta:8.29 prostate:9.07 ovary:8.95 testis:11.36 heart:10.08 muscle:12.10 esophagus:10.53 stomach:8.63 intestine:9.40 colon:8.74 liver/hepato:6.20 lung:9.36 bladder:- kidney:8.09 pituitary:7.40 thyroid/parathyroid:8.41 adrenal gland:8.60 pancreas:9.41 breast:9.35 salivary:9.01
CAGE uterus:4.24 placenta:4.59 prostate:5.02 ovary:5.26 testis:6.00 heart:5.99 muscle:8.35 esophagus:5.66 stomach:- intestine:3.97 colon:4.50     liver/hepato:4.14    lung:5.04 bladder:5.73 kidney:4.42 pituitary:4.20 thyroid/parathyroid:5.25 adrenal gland:- pancreas:5.39 breast:5.29 salivary:3.50
RNA-seq uterus:- placenta:- prostate:7.01 ovary:5.18 testis:6.84 heart:7.22 muscle:12.00 esophagus:- stomach:- intestine:- colon:6.92     liver/hepato:3.32        lung:7.81    bladder:- kidney:5.47 pituitary:- thyroid/parathyroid:8.00 adrenal gland:5.90 pancreas:- breast:6.37 salivary:-

Gene Information

IDs

Refseq ID NM_001145426
Gene ID 8531
Unigene ID Hs.221889
Probe set ID 201161_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000060138
GTEx ID ENSG00000060138

Orthologous Gene

Mouse[4]  NM_011733, NM_139117
Rat[1]  NM_031979, NM_139117

Chromosomal Region

12p13.2  [10,851,683  -  10,875,911]

Gene Family (Interpro ID)

IPR011129  Cold shock protein
IPR002059  Cold-shock protein, DNA-binding

Link to Pubmed  (Pubmed ID)

2977358
7628487
8710501
8871564
9442396
10343102
11799066
12239625
12477932
14728692
15302935
15313206
15489334
15592429
16094384
16159877
16196087
16198352
16344560
16508013
17081983
17620599
17643375
18029348
18781797
19240061
19322201
19328795
19369198
19710015
19734347
19749785
19805454
20020773
20133480
20431927
21139048
21145461
21182205
21282530
21473684
21642987
21890473
21906983
21963094
21987572
22053931
22159460
22505724
22711822
22863883
22939629
22990118
23000965
23084401
23151878
23398456
23463506
23602568
23752268
24244333
24457600
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0070935  3'-UTR-mediated mRNA stabilization
GO:0071474  cellular hyperosmotic response
GO:0071356  cellular response to tumor necrosis factor
GO:0009566  fertilization
GO:0001701  in utero embryonic development
GO:0008584  male gonad development
GO:0043066  negative regulation of apoptosis
GO:0060547  negative regulation of necrotic cell death
GO:0048642  negative regulation of skeletal muscle tissue development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0046622  positive regulation of organ growth
GO:0009409  response to cold
GO:0007283  spermatogenesis
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005844  polysome
GO:0005923  tight junction

Molecular Function

GO:0003690  double-stranded DNA binding
GO:0003730  mRNA 3'-UTR binding
GO:0017048  Rho GTPase binding
GO:0003697  single-stranded DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity