caveolin 3

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Synonym

caveolin 3, LGMD1C, VIP-21, MGC126100, Caveolin-3, VIP21, MGC126129, M-caveolin, CAV3, MGC126101

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:5.90 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip cerebrum:6.09 cerebellum:6.11 brain stem:6.19 corpus callosum/glia:6.03 pineal gland:- peripheral nerve:5.94 spine:6.04 retina:- eye:- artery/aorta:6.30 vein:6.46 lymphnode:5.87 peripheral blood:- spleen:5.81 thymus:5.79 bone marrow:6.29 adipose:6.15 bone:- skin:6.28
CAGE cerebrum:0.03 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0.77 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0.18 vein:0.79 lymphnode:0.57 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:1.12 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:10.90 prostate:22.50 ovary:37.30 testis:- heart:- muscle:100.50 esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.86 placenta:6.11 prostate:5.85 ovary:5.87 testis:5.90 heart:6.81 muscle:8.76 esophagus:6.75 stomach:6.06 intestine:6.78 colon:6.11 liver/hepato:6.15 lung:6.05 bladder:- kidney:6.12 pituitary:5.97 thyroid/parathyroid:5.72 adrenal gland:5.90 pancreas:6.50 breast:5.86 salivary:5.92
CAGE uterus:0.23 placenta:0 prostate:0.33 ovary:0.14 testis:0.10 heart:2.32 muscle:4.04 esophagus:1.04 stomach:- intestine:0.07 colon:0.15     liver/hepato:0    lung:0.54 bladder:0.26 kidney:0 pituitary:0 thyroid/parathyroid:0.23 adrenal gland:- pancreas:0 breast:0 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.02 testis:0.88 heart:2.52 muscle:4.29 esophagus:- stomach:- intestine:- colon:0.23     liver/hepato:0        lung:0.10    bladder:- kidney:0 pituitary:- thyroid/parathyroid:3.83 adrenal gland:0 pancreas:- breast:1.70 salivary:-

Gene Information

IDs

Refseq ID NM_033337
Gene ID 859
Unigene ID Hs.98303
Probe set ID 208204_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000182533
GTEx ID ENSG00000182533

Orthologous Gene

Mouse[1]  NM_007617
Rat [0]  

Chromosomal Region

3p25.3  [8,775,486  -  8,883,492]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

7797570
8567687
9252390
9353265
9374534
9536092
9537420
9545514
9756945
10066366
10386585
10746614
10835421
10988290
11001938
11115849
11251997
11431690
11532985
11756609
11805270
11821059
11884389
11904769
12082049
12387816
12477932
12557291
12648214
12666119
12839838
12847114
12939441
14600260
14663034
14672715
14729862
14749532
14981167
15099591
15489334
15541368
15564037
15580566
15668980
15682833
15703204
16082247
16247063
16458928
16479074
16521037
16563233
16770780
17039257
17060380
17210839
17275750
17307729
17405141
17524427
17537631
17615539
18253147
18487559
18509671
18583131
18671188
18930476
18936328
18985008
19101541
19219452
19238754
19380584
19481058
19544087
19584897
19773168
19913121
20201926
20229577
20301308
20301559
20301582
20301725
20346360
20472890
20558763
20628086
21084288
21294223
21362533
21362625
21496630
21988832
22236542
22879586
23071107
23237801
23311301
23465283
23541953
23640888
24021552

Gene Ontology  (GO ID)

Biological Process

GO:0007015  actin filament organization
GO:0055013  cardiac muscle cell development
GO:0070836  caveola assembly
GO:0030154  cell differentiation
GO:0016049  cell growth
GO:0042632  cholesterol homeostasis
GO:0031122  cytoplasmic microtubule organization
GO:0007204  elevation of cytosolic calcium ion concentration
GO:0006897  endocytosis
GO:0090002  establishment of protein localization in plasma membrane
GO:0042593  glucose homeostasis
GO:0060347  heart trabecula formation
GO:0031579  membrane raft organization
GO:0046716  muscle homeostasis
GO:0007517  muscle organ development
GO:0007520  myoblast fusion
GO:0051926  negative regulation of calcium ion transport
GO:0010614  negative regulation of cardiac muscle hypertrophy
GO:0045792  negative regulation of cell size
GO:0043407  negative regulation of MAP kinase activity
GO:0043409  negative regulation of MAPKKK cascade
GO:0051001  negative regulation of nitric-oxide synthase activity
GO:0006469  negative regulation of protein kinase activity
GO:0060299  negative regulation of sarcomere organization
GO:0051647  nucleus localization
GO:0007009  plasma membrane organization
GO:0001778  plasma membrane repair
GO:0008284  positive regulation of cell proliferation
GO:0031116  positive regulation of microtubule polymerization
GO:0010831  positive regulation of myotube differentiation
GO:0008104  protein localization
GO:0060762  regulation of branching involved in mammary gland duct morphogenesis
GO:0055117  regulation of cardiac muscle contraction
GO:0008016  regulation of heart contraction
GO:0002027  regulation of heart rate
GO:0042391  regulation of membrane potential
GO:0051394  regulation of nerve growth factor receptor activity
GO:0051896  regulation of protein kinase B signaling cascade
GO:0014819  regulation of skeletal muscle contraction
GO:0017015  regulation of transforming growth factor beta receptor signaling pathway
GO:0060373  regulation of ventricular cardiomyocyte membrane depolarization
GO:0060307  regulation of ventricular cardiomyocyte membrane repolarization
GO:0033292  T-tubule organization
GO:0006641  triglyceride metabolic process

Cellular Component

GO:0005901  caveola
GO:0009986  cell surface
GO:0016010  dystrophin-associated glycoprotein complex
GO:0005783  endoplasmic reticulum
GO:0000139  Golgi membrane
GO:0045121  membrane raft
GO:0031594  neuromuscular junction
GO:0005886  plasma membrane
GO:0042383  sarcolemma
GO:0030315  T-tubule
GO:0031982  vesicle
GO:0030018  Z disc

Molecular Function

GO:0043014  alpha-tubulin binding
GO:0005246  calcium channel regulator activity
GO:0071253  connexin binding
GO:0050998  nitric-oxide synthase binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0032403  protein complex binding
GO:0032947  protein complex scaffold
GO:0017080  sodium channel regulator activity