phosphatidic acid phosphatase type 2B

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Synonym

VCIP, Phosphatidate phosphohydrolase type 2b, PPAP2B, Phosphatidic acid phosphatase 2b, PAP2-beta, phosphatidic acid phosphatase type 2B, PAP2b, MGC15306, Lipid phosphate phosphohydrolase 3, LPP3, PAP2-b, Dri42, PAP-2b

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:158.80 cerebellum:176.30 brain stem:- corpus callosum/glia:233.30 pineal gland:148.30 peripheral nerve:306.70 spine:449.20 retina:118.60 eye:217.40 artery/aorta:509.60 vein:66.60 lymphnode:10.10 peripheral blood:18.20 spleen:18.90 thymus:103.10 bone marrow:177.10 adipose:80.70 bone:140.70 skin:249.60
GeneChip cerebrum:9.76 cerebellum:8.90 brain stem:9.55 corpus callosum/glia:10.27 pineal gland:- peripheral nerve:10.10 spine:10.14 retina:- eye:- artery/aorta:10.15 vein:10.63 lymphnode:8.77 peripheral blood:- spleen:8.91 thymus:8.45 bone marrow:7.91 adipose:10.23 bone:- skin:9.69
CAGE cerebrum:4.70 cerebellum:- brain stem:4.45 corpus callosum/glia:5.21 pineal gland:3.19 peripheral nerve:- spine:4.63 retina:- eye:- artery/aorta:4.68 vein:4.39 lymphnode:3.59 peripheral blood:- spleen:3.83 thymus:3.28 bone marrow:- adipose:5.27 bone:- skin:-
RNA-seq cerebrum:5.69 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:5.66 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:5.74 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:300.70 placenta:568.30 prostate:856.10 ovary:37.30 testis:99.50 heart:268.20 muscle:60.30 esophagus:342.80 stomach:21.20 intestine:162 colon:25.40     liver/hepato:63.30        lung:156.40    bladder:251.20 kidney:239.10 pituitary:- thyroid/parathyroid:327.50 adrenal gland:457.10 pancreas:204.50 breast:55.80 salivary:-
GeneChip uterus:10.37 placenta:11.10 prostate:9.85 ovary:10.08 testis:8.98 heart:10.21 muscle:8.42 esophagus:9.62 stomach:10.06 intestine:9.03 colon:10.07 liver/hepato:10.25 lung:10.32 bladder:- kidney:10.36 pituitary:7.79 thyroid/parathyroid:11.76 adrenal gland:10.48 pancreas:8.48 breast:10.42 salivary:9.46
CAGE uterus:5.39 placenta:5.60 prostate:5.36 ovary:5.00 testis:4.71 heart:4.98 muscle:4.24 esophagus:4.73 stomach:- intestine:4.06 colon:4.11     liver/hepato:5.32    lung:4.79 bladder:5.15 kidney:4.76 pituitary:2.89 thyroid/parathyroid:5.69 adrenal gland:- pancreas:3.87 breast:4.76 salivary:4.33
RNA-seq uterus:- placenta:- prostate:6.63 ovary:6.12 testis:6.73 heart:5.03 muscle:3.93 esophagus:- stomach:- intestine:- colon:5.81     liver/hepato:5.23        lung:6.66    bladder:- kidney:5.85 pituitary:- thyroid/parathyroid:7.73 adrenal gland:5.06 pancreas:- breast:5.23 salivary:-

Gene Information

IDs

Refseq ID NM_003713
Gene ID 8613
Unigene ID Hs.405156
Probe set ID 212226_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000162407
GTEx ID ENSG00000162407

Orthologous Gene

Mouse[2]  NM_080555
Rat [0]  

Chromosomal Region

1p32.2  [56,960,419  -  57,110,974]

Gene Family (Interpro ID)

IPR000326  Phosphatidic acid phosphatase type 2/haloperoxidase

Link to Pubmed  (Pubmed ID)

8619474
8889548
9110174
9305923
9705349
10564277
10739957
12471011
12477932
12660161
12856002
14725715
15489334
16099422
16147992
16344560
17005594
17555747
18215144
19913121
20123964
20628086
21139048
21378988
21378990
21569306
21832049
21846871
21906983
21963094
21987572
22837378
23508853
24262325

Gene Ontology  (GO ID)

Biological Process

GO:0001568  blood vessel development
GO:0001702  gastrulation with mouth forming second
GO:0008354  germ cell migration
GO:0034109  homotypic cell-cell adhesion
GO:0006629  lipid metabolic process
GO:0001933  negative regulation of protein amino acid phosphorylation
GO:0006644  phospholipid metabolic process
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0051091  positive regulation of transcription factor activity
GO:0050821  protein stabilization
GO:0030111  regulation of Wnt receptor signaling pathway
GO:0030148  sphingolipid biosynthetic process
GO:0006665  sphingolipid metabolic process

Cellular Component

GO:0005912  adherens junction
GO:0005794  Golgi apparatus
GO:0016021  integral to membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005178  integrin binding
GO:0042577  lipid phosphatase activity
GO:0008195  phosphatidate phosphatase activity
GO:0004721  phosphoprotein phosphatase activity
GO:0005515  protein binding