runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Synonym

ZMYND2, MTG8b, Protein CBFA2T1, Eight twenty one protein, Protein ETO, AML1T1, MTG8, alpha subunit 2; translocated to, RUNX1T1, Cyclin-D-related protein, ETO, runt domain, Zinc finger MYND domain-containing protein 2, Protein MTG8, CBFA2T1, MGC2796

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:270.20

cerebellum:75.60

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:23.50

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:18.90

thymus:-

bone marrow:-

adipose:-

bone:12.80

skin:28.80

GeneChip

cerebrum:6.12

cerebellum:8.27

brain stem:5.89

corpus callosum/glia:4.54

pineal gland:-

peripheral nerve:6.84

spine:5.38

retina:-

eye:-

artery/aorta:6.36

vein:6.07

lymphnode:5.18

peripheral blood:-

spleen:5.51

thymus:3.90

bone marrow:3.90

adipose:6.55

bone:-

skin:5.16

CAGE

cerebrum:3.37

cerebellum:-

brain stem:2.33

corpus callosum/glia:1.92

pineal gland:3.21

peripheral nerve:-

spine:2.44

retina:-

eye:-

artery/aorta:2.99

vein:2.37

lymphnode:1.60

peripheral blood:-

spleen:1.43

thymus:0.54

bone marrow:-

adipose:2.83

bone:-

skin:-

RNA-seq

cerebrum:0.04

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:45.60

placenta:14.60

prostate:67.60

ovary:-

testis:21.60

heart:114.90

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:10.60

lung:24.40

bladder:-

kidney:31.20

pituitary:116

thyroid/parathyroid:-

adrenal gland:-

pancreas:88.90

breast:9.30

salivary:-

GeneChip

uterus:7.20

placenta:5.18

prostate:5.34

ovary:6.37

testis:5.43

heart:6.92

muscle:5.41

esophagus:5.42

stomach:6.43

intestine:5.33

colon:5.59

liver/hepato:4.69

lung:6.46

bladder:-

kidney:4.67

pituitary:6.46

thyroid/parathyroid:6.52

adrenal gland:6.11

pancreas:3.88

breast:7.09

salivary:5.56

CAGE

uterus:3.69

placenta:1.79

prostate:2.79

ovary:2.61

testis:2.49

heart:2.91

muscle:2.37

esophagus:2.52

stomach:-

intestine:1.79

colon:2.68

liver/hepato:0.55

lung:3.02

bladder:2.79

kidney:1.32

pituitary:3.15

thyroid/parathyroid:2.02

adrenal gland:-

pancreas:1.74

breast:3.22

salivary:2.39

RNA-seq

uterus:-

placenta:-

prostate:0.36

ovary:0.53

testis:0.25

heart:0.15

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.21

liver/hepato:0

lung:0.01

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.49

adrenal gland:0.22

pancreas:-

breast:0.25

salivary:-

IDs

Refseq ID	NM_175634
Gene ID	862
Unigene ID	Hs.368431
Probe set ID	205529_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000079102
GTEx ID	ENSG00000079102

Orthologous Gene

Mouse[12]	NM_001111026, NM_001111027, NM_009822
Rat[1]	NM_001108657, NM_001111027, NM_009822

Chromosomal Region

8q21.3 [92,967,203 - 93,115,514]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR013289	Eight-Twenty-One
IPR013290	Myeloid transforming gene on chromosome 8 (MTG8)

Gene Ontology (GO ID)

Biological Process

GO:0045444	fat cell differentiation
GO:0006091	generation of precursor metabolites and energy
GO:0051101	regulation of DNA binding
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0016363

nuclear matrix

Molecular Function

GO:0003677	DNA binding
GO:0042802	identical protein binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0003700	transcription factor activity

runt-related transcription factor 1; translocated to, 1 (cyclin D-related)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function