hydroxysteroid (17-beta) dehydrogenase 6 homolog (mouse)

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Synonym

RODH, hydroxysteroid (17-beta) dehydrogenase 6, 3-hydroxysteroid epimerase, HSD17B6, HSE

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:23.70 cerebellum:37.80 brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:5.90 artery/aorta:30 vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:40.30 bone:- skin:19.20
GeneChip cerebrum:4.41 cerebellum:3.98 brain stem:4.22 corpus callosum/glia:4.04 pineal gland:- peripheral nerve:3.16 spine:3.93 retina:- eye:- artery/aorta:3.55 vein:5.59 lymphnode:2.91 peripheral blood:- spleen:8.01 thymus:2.86 bone marrow:3.01 adipose:3.51 bone:- skin:3.24
CAGE cerebrum:2.14 cerebellum:- brain stem:0.79 corpus callosum/glia:1.11 pineal gland:0.36 peripheral nerve:- spine:0.96 retina:- eye:- artery/aorta:1.10 vein:0.79 lymphnode:0.03 peripheral blood:- spleen:3.20 thymus:0 bone marrow:- adipose:0.26 bone:- skin:-
RNA-seq cerebrum:2.78 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.47 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:7.30 prostate:56.30 ovary:- testis:13 heart:25.50 muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:137.20        lung:9.80    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.75 placenta:4.10 prostate:7.29 ovary:4.49 testis:5.55 heart:4 muscle:3.05 esophagus:3.07 stomach:4.24 intestine:3.60 colon:4.35 liver/hepato:10.77 lung:6.10 bladder:- kidney:2.90 pituitary:2.89 thyroid/parathyroid:7.07 adrenal gland:2.95 pancreas:3.27 breast:3.56 salivary:2.91
CAGE uterus:3.36 placenta:1.57 prostate:3.56 ovary:1.77 testis:2.51 heart:0.29 muscle:0.55 esophagus:0.82 stomach:- intestine:1.37 colon:2.03     liver/hepato:6.46    lung:3.21 bladder:3.74 kidney:0.44 pituitary:0 thyroid/parathyroid:3.94 adrenal gland:- pancreas:0 breast:0 salivary:0.62
RNA-seq uterus:- placenta:- prostate:5.22 ovary:1.82 testis:3.25 heart:0.09 muscle:0.49 esophagus:- stomach:- intestine:- colon:2.54     liver/hepato:8.50        lung:3.56    bladder:- kidney:1.30 pituitary:- thyroid/parathyroid:4.67 adrenal gland:2.41 pancreas:- breast:0.34 salivary:-

Gene Information

IDs

Refseq ID NM_003725
Gene ID 8630
Unigene ID Hs.524513
Probe set ID 37512_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000025423
GTEx ID ENSG00000025423

Orthologous Gene

Mouse[1]  NM_013786
Rat[1]  NM_173305

Chromosomal Region

12q13.3  [57,145,945  -  57,181,574]

Gene Family (Interpro ID)

IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

9188497
10896656
11165032
11306067
11360992
11513953
12477932
16344560
17070195
17207965
17289849
19027726
19837928
20200332
20526338
21039282
22114194
22267201

Gene Ontology  (GO ID)

Biological Process

GO:0006702  androgen biosynthetic process
GO:0006710  androgen catabolic process

Cellular Component

GO:0031901  early endosome membrane
GO:0005783  endoplasmic reticulum
GO:0005622  intracellular

Molecular Function

GO:0047035  3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity
GO:0003824  catalytic activity
GO:0009055  electron carrier activity
GO:0004303  estradiol 17-beta-dehydrogenase activity
GO:0016491  oxidoreductase activity
GO:0004745  retinol dehydrogenase activity