nuclear receptor coactivator 1

Synonym

RIP160, Steroid receptor coactivator 1, NY-REN-52 antigen, nuclear receptor coactivator 1, MGC129720, Nuclear receptor coactivator 1, NCOA1, Protein Hin-2, NCoA-1, SRC1, SRC-1, F-SRC-1, MGC129719

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:1.20

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:8.58

cerebellum:8.70

brain stem:8.32

corpus callosum/glia:8.34

pineal gland:-

peripheral nerve:8.09

spine:8.43

retina:-

eye:-

artery/aorta:8.07

vein:8.14

lymphnode:8.03

peripheral blood:-

spleen:8.18

thymus:8.29

bone marrow:7.88

adipose:8.08

bone:-

skin:8.18

CAGE

cerebrum:1.68

cerebellum:-

brain stem:1.33

corpus callosum/glia:1.33

pineal gland:1.42

peripheral nerve:-

spine:1.10

retina:-

eye:-

artery/aorta:0.69

vein:0.70

lymphnode:0.71

peripheral blood:-

spleen:0.76

thymus:1.18

bone marrow:-

adipose:0.78

bone:-

skin:-

RNA-seq

cerebrum:2.16

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.34

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.89

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:8.23

placenta:7.25

prostate:8.06

ovary:8.27

testis:8.41

heart:8.14

muscle:8.21

esophagus:8.31

stomach:7.98

intestine:7.90

colon:7.71

liver/hepato:7.58

lung:8.13

bladder:-

kidney:8.05

pituitary:8.37

thyroid/parathyroid:7.71

adrenal gland:8.16

pancreas:7.60

breast:8.31

salivary:7.95

CAGE

uterus:0.89

placenta:0.68

prostate:0.81

ovary:0.95

testis:0.85

heart:0.88

muscle:2.37

esophagus:0.82

stomach:-

intestine:1.27

colon:1.05

liver/hepato:0.63

lung:1.18

bladder:0.87

kidney:0.62

pituitary:1.26

thyroid/parathyroid:0.49

adrenal gland:-

pancreas:0.94

breast:0

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:1.64

ovary:3.28

testis:2.80

heart:0.78

muscle:0.07

esophagus:-

stomach:-

intestine:-

colon:1.57

liver/hepato:0.79

lung:1.19

bladder:-

kidney:1.30

pituitary:-

thyroid/parathyroid:0.42

adrenal gland:0.68

pancreas:-

breast:1.13

salivary:-

IDs

Refseq ID	NM_003743
Gene ID	8648
Unigene ID	Hs.596314
Probe set ID	210249_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000084676
GTEx ID	ENSG00000084676

Orthologous Gene

Mouse[2]	NM_010881
Rat [0]

Chromosomal Region

2p23.3 [24,714,783 - 24,993,571]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000014

PAS

Gene Ontology (GO ID)

Biological Process

GO:0030521	androgen receptor signaling pathway
GO:0044255	cellular lipid metabolic process
GO:0043967	histone H4 acetylation
GO:0043065	positive regulation of apoptosis
GO:0045666	positive regulation of neuron differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0000435	positive regulation of transcription from RNA polymerase II promoter by galactose
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0006351	transcription, DNA-dependent

Cellular Component

GO:0000790	nuclear chromatin
GO:0005654	nucleoplasm

Molecular Function

GO:0050681	androgen receptor binding
GO:0003682	chromatin binding
GO:0003677	DNA binding
GO:0019899	enzyme binding
GO:0004402	histone acetyltransferase activity
GO:0016922	ligand-dependent nuclear receptor binding
GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity
GO:0035257	nuclear hormone receptor binding
GO:0005515	protein binding
GO:0046983	protein dimerization activity
GO:0047485	protein N-terminus binding
GO:0004871	signal transducer activity
GO:0003713	transcription coactivator activity

nuclear receptor coactivator 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function