numb homolog (Drosophila)

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Synonym

NUMB, Protein S171, S171, numb homolog (Drosophila), numb (Drosophila) homolog, h-Numb, Protein numb homolog

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:5.29

cerebellum:5.64

brain stem:5.31

corpus callosum/glia:5.29

pineal gland:-

peripheral nerve:6.05

spine:5.49

retina:-

eye:-

artery/aorta:5.75

vein:5.60

lymphnode:5.79

peripheral blood:-

spleen:6.10

thymus:6.10

bone marrow:6.08

adipose:6.11

bone:-

skin:5.95

CAGE

cerebrum:3.82

cerebellum:-

brain stem:3.69

corpus callosum/glia:3.65

pineal gland:3.51

peripheral nerve:-

spine:4.11

retina:-

eye:-

artery/aorta:4.00

vein:3.76

lymphnode:4.00

peripheral blood:-

spleen:4.27

thymus:3.57

bone marrow:-

adipose:4.49

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:1.25

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:6.40

placenta:6.22

prostate:6.20

ovary:6.39

testis:5.94

heart:5.67

muscle:4.76

esophagus:6.06

stomach:6.11

intestine:6.20

colon:6.12

liver/hepato:5.98

lung:6.56

bladder:-

kidney:6.19

pituitary:5.42

thyroid/parathyroid:6.07

adrenal gland:5.54

pancreas:5.39

breast:6.09

salivary:6.37

CAGE

uterus:4.06

placenta:3.69

prostate:3.90

ovary:3.63

testis:3.80

heart:3.69

muscle:3.06

esophagus:3.86

stomach:-

intestine:4.52

colon:4.13

liver/hepato:4.00

lung:4.43

bladder:4.15

kidney:4.08

pituitary:3.91

thyroid/parathyroid:3.71

adrenal gland:-

pancreas:3.93

breast:3.62

salivary:4.44

RNA-seq

uterus:-

placenta:-

prostate:0.96

ovary:0.16

testis:1.86

heart:0.04

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.26

liver/hepato:1.40

lung:0.46

bladder:-

kidney:1.72

pituitary:-

thyroid/parathyroid:1.52

adrenal gland:0.30

pancreas:-

breast:0.48

salivary:-

IDs

Refseq ID	NM_003744
Gene ID	8650
Unigene ID	-
Probe set ID	209073_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000133961
GTEx ID	ENSG00000133961

Orthologous Gene

Mouse[4]	NM_001136075, NM_010949
Rat[1]	NM_133287, NM_010949

Chromosomal Region

14q24.3 [73,741,815 - 73,930,348]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR006020	Phosphotyrosine interaction domain
IPR011993	Pleckstrin homology-type

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

GO:0034332	adherens junction organization
GO:0007411	axon guidance
GO:0021670	lateral ventricle development
GO:0060487	lung epithelial cell differentiation
GO:0045746	negative regulation of Notch signaling pathway
GO:0021849	neuroblast division in the subventricular zone
GO:0007219	Notch signaling pathway
GO:0050769	positive regulation of neurogenesis
GO:0030862	positive regulation of polarized epithelial cell differentiation

Cellular Component

GO:0045177	apical part of cell
GO:0016323	basolateral plasma membrane
GO:0005769	early endosome
GO:0019897	extrinsic to plasma membrane
GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane

Molecular Function

GO:0045294	alpha-catenin binding
GO:0008013	beta-catenin binding
GO:0045296	cadherin binding

numb homolog (Drosophila)

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function