cell division cycle 23 homolog (S. cerevisiae)

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Synonym

Cell division cycle protein 23 homolog, Cyclosome subunit 8, CDC23, CDC23 (cell division cycle 23, yeast, homolog), Anaphase-promoting complex subunit 8, APC8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:8.30 cerebellum:- brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:- spine:- retina:- eye:11.80 artery/aorta:209.80 vein:- lymphnode:30.30 peripheral blood:18.20 spleen:- thymus:77.30 bone marrow:39.40 adipose:40.30 bone:25.60 skin:19.20
GeneChip cerebrum:5.51 cerebellum:5.59 brain stem:5.52 corpus callosum/glia:5.83 pineal gland:- peripheral nerve:6.38 spine:5.82 retina:- eye:- artery/aorta:6.03 vein:5.69 lymphnode:6.10 peripheral blood:- spleen:6.49 thymus:6.85 bone marrow:6.05 adipose:6.25 bone:- skin:6.29
CAGE cerebrum:2.73 cerebellum:- brain stem:2.67 corpus callosum/glia:2.81 pineal gland:2.80 peripheral nerve:- spine:2.43 retina:- eye:- artery/aorta:2.48 vein:2.09 lymphnode:2.69 peripheral blood:- spleen:2.65 thymus:2.64 bone marrow:- adipose:2.51 bone:- skin:-
RNA-seq cerebrum:2.52 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.73 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.90 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:29.10 prostate:- ovary:- testis:60.60 heart:- muscle:- esophagus:- stomach:- intestine:- colon:42.40     liver/hepato:10.60        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip uterus:6.70 placenta:6.88 prostate:6.82 ovary:6.54 testis:6.38 heart:5.78 muscle:5.98 esophagus:6.25 stomach:6.10 intestine:5.69 colon:5.98 liver/hepato:6 lung:5.83 bladder:- kidney:6.25 pituitary:5.79 thyroid/parathyroid:6.35 adrenal gland:5.81 pancreas:4.80 breast:6.65 salivary:5.53
CAGE uterus:2.53 placenta:3.12 prostate:2.46 ovary:2.45 testis:2.57 heart:2.32 muscle:1.83 esophagus:2.60 stomach:- intestine:2.44 colon:2.37     liver/hepato:2.79    lung:2.52 bladder:2.51 kidney:2.84 pituitary:2.82 thyroid/parathyroid:2.47 adrenal gland:- pancreas:2.86 breast:2.53 salivary:2.26
RNA-seq uterus:- placenta:- prostate:3.30 ovary:3.38 testis:3.38 heart:2.66 muscle:1.97 esophagus:- stomach:- intestine:- colon:2.62     liver/hepato:2.62        lung:2.33    bladder:- kidney:3.37 pituitary:- thyroid/parathyroid:3.10 adrenal gland:3.10 pancreas:- breast:3.20 salivary:-

Gene Information

IDs

Refseq ID NM_004661
Gene ID 8697
Unigene ID Hs.73625
Probe set ID 202892_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000094880
GTEx ID ENSG00000094880

Orthologous Gene

Mouse[2]  NM_178347
Rat[1]  NM_001100659

Chromosomal Region

5q31.2  [137,523,339  -  137,549,032]

Gene Family (Interpro ID)

IPR019734  Tetratricopeptide repeat

Link to Pubmed  (Pubmed ID)

8125298
9469815
9790767
10318877
10500174
10548110
10793135
10922056
11076961
11256614
11285280
11340163
11535616
11742988
12070128
12188893
12477932
12629511
12956947
14593737
14657031
15029244
15302935
15345747
15489334
16189514
16364912
16565220
16648845
16921029
16964243
17081983
17609108
17942546
18162579
18485873
18997788
19322201
19531213
20080579
20360068
21043528
21139048
21336306
21549307
21906983
21963094
21990323
22014574
22193957
22280307
22505724
22792066
22939629
22990118
23000965
23007861
23022380
23160376
23455924
23667531
23708001
23979597
24163370

Gene Ontology  (GO ID)

Biological Process

GO:0031145  anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0007049  cell cycle
GO:0051301  cell division
GO:0000080  G1 phase of mitotic cell cycle
GO:0007067  mitosis
GO:0000278  mitotic cell cycle
GO:0007094  mitotic cell cycle spindle assembly checkpoint
GO:0007080  mitotic metaphase plate congression
GO:0007091  mitotic metaphase/anaphase transition
GO:0051436  negative regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0051437  positive regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0070979  protein K11-linked ubiquitination
GO:0007096  regulation of exit from mitosis
GO:0030071  regulation of mitotic metaphase/anaphase transition
GO:0051439  regulation of ubiquitin-protein ligase activity during mitotic cell cycle
GO:0006511  ubiquitin-dependent protein catabolic process

Cellular Component

GO:0005680  anaphase-promoting complex
GO:0005829  cytosol
GO:0005622  intracellular
GO:0005654  nucleoplasm

Molecular Function

GO:0004842  ubiquitin-protein ligase activity