endothelial differentiation-related factor 1

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Synonym

EDF-1, endothelial differentiation-related factor 1, Endothelial differentiation-related factor 1, EDF1, MBF1, Multiprotein-bridging factor 1, MGC9058

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:59.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:99.90 artery/aorta:89.90 vein:266.60 lymphnode:91 peripheral blood:18.20 spleen:- thymus:- bone marrow:59 adipose:- bone:- skin:72
GeneChip cerebrum:8.45 cerebellum:8.58 brain stem:8.66 corpus callosum/glia:8.29 pineal gland:- peripheral nerve:8.75 spine:8.35 retina:- eye:- artery/aorta:8.82 vein:8.47 lymphnode:8.70 peripheral blood:- spleen:8.34 thymus:8.59 bone marrow:7.98 adipose:8.49 bone:- skin:8.94
CAGE cerebrum:5.66 cerebellum:- brain stem:5.31 corpus callosum/glia:5.21 pineal gland:5.37 peripheral nerve:- spine:5.81 retina:- eye:- artery/aorta:6.10 vein:5.99 lymphnode:5.77 peripheral blood:- spleen:5.38 thymus:5.25 bone marrow:- adipose:5.38 bone:- skin:-
RNA-seq cerebrum:7.30 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:7.24 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:7.49 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:36.50 placenta:21.90 prostate:236.60 ovary:186.30 testis:13 heart:140.50 muscle:221 esophagus:- stomach:21.20 intestine:32.40 colon:50.90     liver/hepato:73.90        lung:44    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:151.10 breast:18.60 salivary:-
GeneChip uterus:8.86 placenta:8.26 prostate:9.25 ovary:9.21 testis:8.55 heart:8.53 muscle:8.38 esophagus:9.05 stomach:8.45 intestine:8.71 colon:8.54 liver/hepato:8.76 lung:8.60 bladder:- kidney:8.81 pituitary:8.76 thyroid/parathyroid:9.11 adrenal gland:8.68 pancreas:9.24 breast:8.90 salivary:9.33
CAGE uterus:5.72 placenta:5.41 prostate:5.63 ovary:5.73 testis:5.47 heart:5.95 muscle:6.39 esophagus:5.74 stomach:- intestine:6.17 colon:5.91     liver/hepato:6.14    lung:5.63 bladder:5.64 kidney:5.71 pituitary:5.57 thyroid/parathyroid:5.65 adrenal gland:- pancreas:7.16 breast:5.99 salivary:6.61
RNA-seq uterus:- placenta:- prostate:7.96 ovary:7.89 testis:7.82 heart:6.27 muscle:7.16 esophagus:- stomach:- intestine:- colon:7.67     liver/hepato:7.35        lung:7.44    bladder:- kidney:7.45 pituitary:- thyroid/parathyroid:7.79 adrenal gland:7.73 pancreas:- breast:7.56 salivary:-

Gene Information

IDs

Refseq ID NM_003792
Gene ID 8721
Unigene ID Hs.174050
Probe set ID 209059_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000107223
GTEx ID ENSG00000107223

Orthologous Gene

Mouse[2]  NM_021519
Rat[1]  NM_001106557

Chromosomal Region

9q34.3  [139,756,571  -  139,760,738]

Gene Family (Interpro ID)

IPR001387  Helix-turn-helix type 3
IPR010982  Lambda repressor-like, DNA-binding

Link to Pubmed  (Pubmed ID)

7566098
8164657
9813014
10469174
10567391
10816571
12040021
12477932
15112053
15164053
15489334
16567061
16880509
17709345
18029348
20972266
21139048
21782027
21890473
21900206
21906983
22939629
23000965
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0045446  endothelial cell differentiation
GO:0007275  multicellular organismal development
GO:0043388  positive regulation of DNA binding
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0019216  regulation of lipid metabolic process
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005622  intracellular
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005669  transcription factor TFIID complex

Molecular Function

GO:0005516  calmodulin binding
GO:0004402  histone acetyltransferase activity
GO:0008168  methyltransferase activity
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003713  transcription coactivator activity
GO:0003700  transcription factor activity