ADAM metallopeptidase domain 9 (meltrin gamma)

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Synonym

Mltng, MDC9, MCMP, Meltrin gamma, A disintegrin and metalloproteinase domain 9, ADAM 9 precursor, ADAM metallopeptidase domain 9 (meltrin gamma), MLTNG, Cellular disintegrin-related protein, ADAM9, KIAA0021, Myeloma cell metalloproteinase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:17.80 cerebellum:- brain stem:- corpus callosum/glia:116.60 pineal gland:- peripheral nerve:30.70 spine:224.60 retina:- eye:29.40 artery/aorta:209.80 vein:133.30 lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:98.40 adipose:40.30 bone:51.20 skin:33.60
GeneChip nodata
CAGE cerebrum:3.57 cerebellum:- brain stem:3.67 corpus callosum/glia:3.39 pineal gland:3.72 peripheral nerve:- spine:3.86 retina:- eye:- artery/aorta:4.30 vein:3.47 lymphnode:3.59 peripheral blood:- spleen:4.06 thymus:1.86 bone marrow:- adipose:4.47 bone:- skin:-
RNA-seq cerebrum:0.07 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.65 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:72.90 prostate:78.90 ovary:74.50 testis:26 heart:51.10 muscle:20.10 esophagus:- stomach:318.60 intestine:- colon:161.10     liver/hepato:21.10        lung:78.20    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:53.30 breast:204.40 salivary:-
GeneChip nodata
CAGE uterus:3.92 placenta:4.13 prostate:3.92 ovary:3.66 testis:3.54 heart:4.04 muscle:3.37 esophagus:3.89 stomach:- intestine:4.04 colon:3.80     liver/hepato:3.13    lung:4.39 bladder:4.34 kidney:4.15 pituitary:3.22 thyroid/parathyroid:3.93 adrenal gland:- pancreas:3.10 breast:3.66 salivary:3.49
RNA-seq uterus:- placenta:- prostate:0.88 ovary:0.07 testis:0.24 heart:0.00 muscle:0.16 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.24    bladder:- kidney:1.02 pituitary:- thyroid/parathyroid:0.36 adrenal gland:0.14 pancreas:- breast:0.13 salivary:-

Gene Information

IDs

Refseq ID NR_027878
Gene ID 8754
Unigene ID Hs.591852
Probe set ID -
Ensembl ID -
GTEx ID -

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

8p11.22  [38,854,388  -  38,962,663]

Gene Family (Interpro ID)

IPR000742  EGF-like, type 3

Link to Pubmed  (Pubmed ID)

7584026
7584028
8647900
8809033
9016778
9857183
9920899
10527948
10531379
11162558
11581183
11831872
11882657
11955914
12054541
12135759
12477932
12484779
12535668
12767059
14997207
15205330
15280379
15361064
15856464
16311053
16336960
16806063
17018608
17081983
17342749
17704059
18061337
19003995
19237226
19253070
19394555
19409519
19473694
19505527
19543729
19564338
20388695
20422344
20672324
20736367
21135106
21139048
21906983
21956108
21963094
21987572
22064652
22480688
23000965
23106877
23342005
23405089
23429442
23437250
23499592
23857158
24457600

Gene Ontology  (GO ID)

Biological Process

GO:0000186  activation of MAPKK activity
GO:0007155  cell adhesion
GO:0033627  cell adhesion mediated by integrin
GO:0033631  cell-cell adhesion mediated by integrin
GO:0007160  cell-matrix adhesion
GO:0071222  cellular response to lipopolysaccharide
GO:0030574  collagen catabolic process
GO:0022617  extracellular matrix disassembly
GO:0030198  extracellular matrix organization
GO:0007229  integrin-mediated signaling pathway
GO:0030216  keratinocyte differentiation
GO:0006509  membrane protein ectodomain proteolysis
GO:0042117  monocyte activation
GO:0051088  PMA-inducible membrane protein ectodomain proteolysis
GO:0033630  positive regulation of cell adhesion mediated by integrin
GO:0051549  positive regulation of keratinocyte migration
GO:0034241  positive regulation of macrophage fusion
GO:0051044  positive regulation of membrane protein ectodomain proteolysis
GO:0050714  positive regulation of protein secretion
GO:0051592  response to calcium ion
GO:0051384  response to glucocorticoid stimulus
GO:0042542  response to hydrogen peroxide
GO:0010042  response to manganese ion
GO:0034612  response to tumor necrosis factor
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0031233  intrinsic to external side of plasma membrane

Molecular Function

GO:0005518  collagen binding
GO:0005178  integrin binding
GO:0043236  laminin binding
GO:0004222  metalloendopeptidase activity
GO:0008237  metallopeptidase activity
GO:0005515  protein binding
GO:0005080  protein kinase C binding
GO:0017124  SH3 domain binding
GO:0008270  zinc ion binding