tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Synonym

Osteoclast differentiation factor receptor, ODFR, CD265 antigen, TNFRSF11A, CD265, Receptor activator of NF-KB, member 11a, TRANCER, OFE, RANK

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:2.40

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:66.60

lymphnode:10.10

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:9.60

GeneChip

cerebrum:3.58

cerebellum:3.69

brain stem:3.63

corpus callosum/glia:3.55

pineal gland:-

peripheral nerve:3.83

spine:3.71

retina:-

eye:-

artery/aorta:3.88

vein:3.62

lymphnode:3.86

peripheral blood:-

spleen:3.59

thymus:3.74

bone marrow:3.73

adipose:3.69

bone:-

skin:3.99

CAGE

cerebrum:0.86

cerebellum:-

brain stem:0.63

corpus callosum/glia:0.85

pineal gland:0.26

peripheral nerve:-

spine:0.90

retina:-

eye:-

artery/aorta:1.33

vein:1.83

lymphnode:1.90

peripheral blood:-

spleen:0.32

thymus:0.64

bone marrow:-

adipose:2.28

bone:-

skin:-

RNA-seq

cerebrum:0.43

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.68

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.28

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:3.60

prostate:45.10

ovary:-

testis:-

heart:25.50

muscle:-

esophagus:-

stomach:21.20

intestine:-

colon:25.40

liver/hepato:-

lung:4.90

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:35.60

breast:-

salivary:-

GeneChip

uterus:3.78

placenta:3.98

prostate:3.82

ovary:3.61

testis:3.70

heart:3.56

muscle:3.77

esophagus:3.98

stomach:3.86

intestine:4.29

colon:4.69

liver/hepato:3.65

lung:3.58

bladder:-

kidney:3.50

pituitary:4.41

thyroid/parathyroid:3.68

adrenal gland:3.57

pancreas:4.07

breast:3.91

salivary:5.91

CAGE

uterus:0.87

placenta:1.55

prostate:1.14

ovary:0.68

testis:1.08

heart:0.68

muscle:0.35

esophagus:1.29

stomach:-

intestine:3.45

colon:3.38

liver/hepato:0.36

lung:1.41

bladder:0.91

kidney:0.95

pituitary:2.59

thyroid/parathyroid:0.67

adrenal gland:-

pancreas:1.59

breast:2.02

salivary:3.90

RNA-seq

uterus:-

placenta:-

prostate:0.82

ovary:0.25

testis:0.88

heart:0.33

muscle:0.05

esophagus:-

stomach:-

intestine:-

colon:0.89

liver/hepato:0.20

lung:0.29

bladder:-

kidney:0.50

pituitary:-

thyroid/parathyroid:0.72

adrenal gland:2.02

pancreas:-

breast:0.84

salivary:-

IDs

Refseq ID	NM_003839
Gene ID	8792
Unigene ID	Hs.204044
Probe set ID	207037_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000141655
GTEx ID	ENSG00000141655

Orthologous Gene

Mouse[1]	NM_009399
Rat[1]	NM_009399

Chromosomal Region

18q21.33 [59,992,520 - 60,054,899]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

LRG_194 [5,001 - 65,957]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0002250	adaptive immune response
GO:0007267	cell-cell signaling
GO:0060086	circadian temperature homeostasis
GO:0048535	lymph node development
GO:0060749	mammary gland alveolus development
GO:0002548	monocyte chemotaxis
GO:0001503	ossification
GO:0030316	osteoclast differentiation
GO:0008284	positive regulation of cell proliferation
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0043507	positive regulation of JUN kinase activity
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051091	positive regulation of transcription factor activity
GO:0034097	response to cytokine stimulus
GO:0070555	response to interleukin-1
GO:0032496	response to lipopolysaccharide
GO:0009314	response to radiation
GO:0034612	response to tumor necrosis factor
GO:0007165	signal transduction
GO:0033209	tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane

Molecular Function

GO:0019955	cytokine binding
GO:0046872	metal ion binding
GO:0005515	protein binding
GO:0004872	receptor activity
GO:0004888	transmembrane receptor activity
GO:0005031	tumor necrosis factor receptor activity

tumor necrosis factor receptor superfamily, member 11a, NFKB activator

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function